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Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

Perfect Domination Problem (PDP), a canonical challenge in combinatorial optimization, finds critical applications in real-world systems such as error-correcting codes, wireless communication networks, and social networks. Decades of…

Quantum Physics · Physics 2025-09-18 Haoqian Pan , Changhong Lu , Yuqing Zheng , Chunxing Yan

Variational Quantum optimization algorithms, such as the Variational Quantum Eigensolver (VQE) or the Quantum Approximate Optimization Algorithm (QAOA), are among the most studied quantum algorithms. In our work, we evaluate and improve an…

Quantum Physics · Physics 2022-10-24 David Winderl , Nicola Franco , Jeanette Miriam Lorenz

Quantum optimization holds promise for addressing classically intractable combinatorial problems, yet a standardized framework for benchmarking its performance, particularly in terms of solution quality, computational speed, and scalability…

Quantum Physics · Physics 2025-03-20 Monit Sharma , Hoong Chuin Lau

Von Neumann projections are the main operations by which information can be extracted from the quantum to the classical realm. They are however static processes that do not adapt to the states they measure. Advances in the field of adaptive…

Quantum Physics · Physics 2015-10-28 Amine Laghaout , Ulrik L. Andersen

Many combinatorial optimization problems admit a maximin fairness variant, where the aim is to find a distribution over possible solutions which maximizes an expected worst-case outcome. However, the support for an optimal distribution may…

Quantum Physics · Physics 2026-04-17 Bao Bach , Cameron Ibrahim , Reuben Tate , Jad Salem , Stephan Eidenbenz , Ilya Safro

Parameterized quantum circuits are widely studied approaches for tackling optimization problems. A prominent example is the Quantum Alternating Operator Ansatz (QAOA), an approach that builds off the structure of the Quantum Approximate…

Quantum Physics · Physics 2022-11-18 James Sud , Stuart Hadfield , Eleanor Rieffel , Norm Tubman , Tad Hogg

Until high-fidelity quantum computers with a large number of qubits become widely available, classical simulation remains a vital tool for algorithm design, tuning, and validation. We present a simulator for the Quantum Approximate…

Quantum Physics · Physics 2023-11-14 Danylo Lykov , Ruslan Shaydulin , Yue Sun , Yuri Alexeev , Marco Pistoia

The Quantum Approximate Optimisation Algorithm (QAOA) is a hybrid quantum-classical algorithm for solving combinatorial optimisation problems. QAOA encodes solutions into the ground state of a Hamiltonian, approximated by a $p$-level…

Quantum Physics · Physics 2025-05-16 V Vijendran , Dax Enshan Koh , Eunok Bae , Hyukjoon Kwon , Ping Koy Lam , Syed M Assad

There is a large ongoing research effort towards obtaining a quantum advantage in the solution of combinatorial optimization problems on near-term quantum devices. A particularly promising platform for testing and developing quantum…

The major advances in quantum computing over the last few decades have sparked great interest in applying it to solve the most challenging computational problems in a wide variety of areas. One of the most pronounced domains here are…

Quantum Physics · Physics 2024-04-11 Andreas Sturm , Bharadwaj Mummaneni , Leon Rullkötter

The Quantum Approximate Optimization Algorithm (QAOA) is expected to offer advantages over classical approaches when solving combinatorial optimization problems in the Noisy Intermediate-Scale Quantum (NISQ) era. In its standard…

Quantum Physics · Physics 2026-03-06 Arkadiusz Wołk , Karol Capała , Katarzyna Rycerz

Quantum computing is gaining popularity across a wide range of scientific disciplines due to its potential to solve long-standing computational problems that are considered intractable with classical computers. One promising area where…

Quantum Physics · Physics 2023-05-15 Benjamin C. B. Symons , David Galvin , Emre Sahin , Vassil Alexandrov , Stefano Mensa

The Quantum Approximate Optimization Algorithm (QAOA) is a well-known hybrid quantum-classical algorithm for combinatorial optimization problems. Improving QAOA involves enhancing its approximation ratio while addressing practical…

Quantum Physics · Physics 2025-02-07 Yukun Wang , ZeYang Li , Linchun Wan

Motivated by the recent advancement of quantum processors, we investigate quantum approximate optimization algorithm (QAOA) to employ quasi-maximum-likelihood (ML) decoding of classical channel codes. QAOA is a hybrid quantum-classical…

Information Theory · Computer Science 2019-03-07 Toshiki Matsumine , Toshiaki Koike-Akino , Ye Wang

We demonstrate the application of the Google Sycamore superconducting qubit quantum processor to combinatorial optimization problems with the quantum approximate optimization algorithm (QAOA). Like past QAOA experiments, we study…

A frequent starting point of quantum computation platforms are two-state quantum systems, i.e., qubits. However, in the context of integer optimization problems, relevant to scheduling optimization and operations research, it is often more…

The quantum approximate optimization algorithm (QAOA) is a leading candidate algorithm for solving optimization problems on quantum computers. However, the potential of QAOA to tackle classically intractable problems remains unclear. Here,…

Multiple-input multiple-output (MIMO) is critical for 6G communication, offering improved spectral efficiency and reliability. However, conventional fully digital designs face significant challenges due to high hardware complexity and power…

Emerging Technologies · Computer Science 2025-10-21 Nikos A Mitsiou , Ioannis Krikidis , George K Karagiannidis

In order to qualify quantum algorithms for industrial NP-Hard problems, comparing them to available polynomial approximate classical algorithms and not only to exact ones -- exponential by nature -- , is necessary. This is a great challenge…