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Challenges in natural sciences can often be phrased as optimization problems. Machine learning techniques have recently been applied to solve such problems. One example in chemistry is the design of tailor-made organic materials and…

Neural and Evolutionary Computing · Computer Science 2020-01-17 AkshatKumar Nigam , Pascal Friederich , Mario Krenn , Alán Aspuru-Guzik

Polygenic risk scores (PRS) estimate the genetic risk of an individual for a complex disease based on many genetic variants across the whole genome. In this study, we compared a series of computational models for estimation of breast cancer…

Quantitative Methods · Quantitative Biology 2023-07-26 Adrien Badré , Li Zhang , Wellington Muchero , Justin C. Reynolds , Chongle Pan

Convolutional neural networks (CNNs) are effective at solving difficult problems like visual recognition, speech recognition and natural language processing. However, performance gain comes at the cost of laborious trial-and-error in…

Neural and Evolutionary Computing · Computer Science 2018-12-20 Yiheng Zhu , Yichen Yao , Zili Wu , Yujie Chen , Guozheng Li , Haoyuan Hu , Yinghui Xu

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Xueli Xiao , Ming Yan , Sunitha Basodi , Chunyan Ji , Yi Pan

Directed acyclic graphs (DAGs) are central to science and engineering applications including causal inference, scheduling, and neural architecture search. In this work, we introduce the DAG Convolutional Network (DCN), a novel graph neural…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Samuel Rey , Hamed Ajorlou , Gonzalo Mateos

Steerable properties dominate the design of traditional filters, e.g., Gabor filters, and endow features the capability of dealing with spatial transformations. However, such excellent properties have not been well explored in the popular…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Shangzhen Luan , Baochang Zhang , Chen Chen , Xianbin Cao , Jungong Han , Jianzhuang Liu

Cellular reprogramming, the artificial transformation of one cell type into another, has been attracting increasing research attention due to its therapeutic potential for complex diseases. However, identifying effective reprogramming…

Machine Learning · Computer Science 2025-11-18 Andrzej Mizera , Jakub Zarzycki

One of the main and largely unexplored challenges in evolving the weights of neural networks using genetic algorithms is to find a sensible crossover operation between parent networks. Indeed, naive crossover leads to functionally damaged…

Neural and Evolutionary Computing · Computer Science 2020-11-17 Thomas Uriot , Dario Izzo

The choice of parameters, and the design of the network architecture are important factors affecting the performance of deep neural networks. Genetic Algorithms (GA) have been used before to determine parameters of a network. Yet, GAs…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Yantao Lu , Burak Kakillioglu , Senem Velipasalar

Building large models with parameter sharing accounts for most of the success of deep convolutional neural networks (CNNs). In this paper, we propose doubly convolutional neural networks (DCNNs), which significantly improve the performance…

Machine Learning · Computer Science 2016-11-01 Shuangfei Zhai , Yu Cheng , Weining Lu , Zhongfei Zhang

Deep convolutional neural network (DCNN) based supervised learning is a widely practiced approach for large-scale image classification. However, retraining these large networks to accommodate new, previously unseen data demands high…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Syed Shakib Sarwar , Aayush Ankit , Kaushik Roy

Deep Convolutional Neural Networks (DCNNs) is currently the method of choice both for generative, as well as for discriminative learning in computer vision and machine learning. The success of DCNNs can be attributed to the careful…

Deep neuroevolution and deep reinforcement learning (deep RL) algorithms are two popular approaches to policy search. The former is widely applicable and rather stable, but suffers from low sample efficiency. By contrast, the latter is more…

Machine Learning · Computer Science 2019-02-12 Aloïs Pourchot , Olivier Sigaud

Gravitational-wave detection strategies are based on a signal analysis technique known as matched filtering. Despite the success of matched filtering, due to its computational cost, there has been recent interest in developing deep…

General Relativity and Quantum Cosmology · Physics 2022-11-03 Dwyer S. Deighan , Scott E. Field , Collin D. Capano , Gaurav Khanna

We introduce Dynamic Deep Neural Networks (D2NN), a new type of feed-forward deep neural network that allows selective execution. Given an input, only a subset of D2NN neurons are executed, and the particular subset is determined by the…

Machine Learning · Computer Science 2018-03-06 Lanlan Liu , Jia Deng

State-of-the-art Deep Neural Networks (DNNs) often incorporate multi-branch connections, enabling multi-scale feature extraction and enhancing the capture of diverse features. This design improves network capacity and generalisation to…

Neural and Evolutionary Computing · Computer Science 2025-06-26 Fergal Stapleton , Daniel García Núñez , Yanan Sun , Edgar Galván

Aim/Introduction: Distance-encoding biomorphic-informational neural network (DEBI-NN) is a recently proposed architecture in which connection weights are defined by the distances between neurons positioned in a Euclidian space. This…

Neural and Evolutionary Computing · Computer Science 2026-05-28 Amine Boukhari , Boglarka Ecsedi , Laszlo Papp , Mathieu Hatt

Deep reinforcement learning (DRL) has been widely used for dynamic algorithm configuration, particularly in evolutionary computation, which benefits from the adaptive update of parameters during the algorithmic execution. However, applying…

Neural and Evolutionary Computing · Computer Science 2025-05-27 Robbert Reijnen , Yaoxin Wu , Zaharah Bukhsh , Yingqian Zhang

Despite a lack of theoretical understanding, deep neural networks have achieved unparalleled performance in a wide range of applications. On the other hand, shallow representation learning with component analysis is associated with rich…

Machine Learning · Computer Science 2018-03-20 Calvin Murdock , Ming-Fang Chang , Simon Lucey

Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and…

Machine Learning · Computer Science 2019-12-16 Siddhartha Dhar Choudhury , Shashank Pandey , Kunal Mehrotra