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Game theory has been an effective tool in the control of disease spread and in suggesting optimal policies at both individual and area levels. In this AMS Notices article, we focus on the decision-making development for the intervention of…

Optimization and Control · Mathematics 2022-08-19 Yao Xuan , Robert Balkin , Jiequn Han , Ruimeng Hu , Hector D. Ceniceros

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

Machine Learning · Computer Science 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

We study the problem of learning sequential decision-making policies in settings with multiple state-action representations. Such settings naturally arise in many domains, such as planning (e.g., multiple integer programming formulations)…

Machine Learning · Computer Science 2019-07-11 Jialin Song , Ravi Lanka , Yisong Yue , Masahiro Ono

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

Much of the micro data used for epidemiological studies contain sensitive measurements on real individuals. As a result, such micro data cannot be published out of privacy concerns, rendering any published statistical analyses on them…

Methodology · Statistics 2022-01-20 Joseph Feldman , Daniel Kowal

Over a year after the start of the COVID-19 epidemics, we are still facing the virus and it is hard to correctly predict its future spread over weeks to come, as well as the impacts of potential political interventions. Current epidemic…

Multiagent Systems · Computer Science 2021-12-03 Benoit Doussin , Carole Adam , Didier Georges

Deep reinforcement learning with domain randomization learns a control policy in various simulations with randomized physical and sensor model parameters to become transferable to the real world in a zero-shot setting. However, a huge…

Robotics · Computer Science 2023-04-11 Yuki Kadokawa , Lingwei Zhu , Yoshihisa Tsurumine , Takamitsu Matsubara

Policy researchers using synthetic control methods typically choose a donor pool in part by using policy domain expertise so the untreated units are most like the treated unit in the pre intervention period. This potentially leaves…

Econometrics · Economics 2023-08-29 Jared Amani Greathouse , Mani Bayani , Jason Coupet

Reactive synthesis is a class of methods to construct a provably-correct control system, referred to as a robot, with respect to a temporal logic specification in the presence of a dynamic and uncontrollable environment. This is achieved by…

Formal Languages and Automata Theory · Computer Science 2020-04-24 Abhishek N. Kulkarni , Jie Fu

Optimal state-feedback controllers, capable of changing between different objective functions, are advantageous to systems in which unexpected situations may arise. However, synthesising such controllers, even for a single objective, is a…

Systems and Control · Computer Science 2020-10-13 Christopher Iliffe Sprague , Dario Izzo , Petter Ögren

Contemporary Epidemiological Surveillance (ES) relies heavily on data analytics. These analytics are critical input for pandemics preparedness networks; however, this input is not integrated into a form suitable for decision makers or…

Artificial Intelligence · Computer Science 2020-08-11 Svetlana Yanushkevich , Vlad Shmerko

Consider making a prediction over new test data without any opportunity to learn from a training set of labelled data - instead given access to a set of expert models and their predictions alongside some limited information about the…

Machine Learning · Computer Science 2022-10-12 Alex J. Chan , Mihaela van der Schaar

We propose a kinetic model for understanding the link between opinion formation phenomena and epidemic dynamics. The recent pandemic has brought to light that vaccine hesitancy can present different phases and temporal and spatial…

Physics and Society · Physics 2023-10-31 Andrea Bondesan , Giuseppe Toscani , Mattia Zanella

Epidemics exhibit interconnected processes that operate at multiple time and organizational scales, a hallmark of complex adaptive systems. Modern epidemiological modeling frameworks incorporate feedback between individual-level behavioral…

Dynamical Systems · Mathematics 2025-03-07 Baltazar Espinoza , Roger Sanchez , Jimmy Calvo-Monge , Fabio Sanchez

Critical scenario generation requires the ability of sampling critical combinations from the infinite parameter space in the logic scenario. Existing solutions aim to explore the correlation of action parameters in the initial scenario…

Artificial Intelligence · Computer Science 2023-01-13 Shuting Kang , Heng Guo , Lijun Zhang , Guangzhen Liu , Yunzhi Xue , Yanjun Wu

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

Computation · Statistics 2015-09-15 Michael Ludkovski , Katherine Shatskikh

Epidemiologists have a growing interest in employing computational approaches to solve analytic problems, with simulation being arguably the most accessible among all approaches. While previous literature discussed the utility of simulation…

Computation · Statistics 2023-06-22 Boyi Guo , Linzi Li , Jacqueline E. Rudolph

Real-world autonomous driving, particularly in urban environments with numerous corner cases, requires rigorous testing to ensure product safety and robustness. However, few studies have explored integrating adversarial scenario generation…

Robotics · Computer Science 2026-05-18 Chuancheng Zhang , Zhenhao Wang , Kaizheng Li , Yaran Lin , Qiang Guo , Bin Jiang

We address the problem of policy selection in contextual stochastic optimization (CSO), where covariates are available as contextual information and decisions must satisfy hard feasibility constraints. In many CSO settings, multiple…

Machine Learning · Computer Science 2026-05-29 Caio de Prospero Iglesias , Kimberly Villalobos Carballo , Dimitris Bertsimas

Decision making in the face of a disaster requires the consideration of several complex factors. In such cases, Bayesian multi-criteria decision analysis provides a framework for decision making. In this paper, we present how to construct a…

Applications · Statistics 2021-12-21 Peter Strong , Aditi Shenvi , Xuewen Yu , K. Nadia Papamichail , Henry P Wynn , Jim Q Smith