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Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Many companies use large language models (LLMs) offered as a service, like OpenAI's GPT-4, to create AI-enabled product experiences. Along with the benefits of ease-of-use and shortened time-to-solution, this reliance on proprietary…

Scientific research is inherently global. However, the vast majority of academic journals are published exclusively in English, creating barriers for non-native-English-speaking researchers. In this study, we leverage large language models…

Artificial Intelligence · Computer Science 2025-09-05 Hannah Calzi Kleidermacher , James Zou

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Computers and Society · Computer Science 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

This paper provides a comprehensive survey of the latest research on multilingual large language models (MLLMs). MLLMs not only are able to understand and generate language across linguistic boundaries, but also represent an important…

Computation and Language · Computer Science 2024-11-20 Shaolin Zhu , Supryadi , Shaoyang Xu , Haoran Sun , Leiyu Pan , Menglong Cui , Jiangcun Du , Renren Jin , António Branco , Deyi Xiong

Generative artificial intelligence attracts significant attention, especially with the introduction of large language models. Its capabilities are being exploited to solve various software engineering tasks. Thanks to their ability to…

Software Engineering · Computer Science 2026-02-06 Lukas Radosky , Ivan Polasek

We present ControlLLM, a novel framework that enables large language models (LLMs) to utilize multi-modal tools for solving complex real-world tasks. Despite the remarkable performance of LLMs, they still struggle with tool invocation due…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Zhaoyang Liu , Zeqiang Lai , Zhangwei Gao , Erfei Cui , Ziheng Li , Xizhou Zhu , Lewei Lu , Qifeng Chen , Yu Qiao , Jifeng Dai , Wenhai Wang

Algorithm design is crucial for effective problem-solving across various domains. The advent of Large Language Models (LLMs) has notably enhanced the automation and innovation within this field, offering new perspectives and promising…

Machine Learning · Computer Science 2026-01-06 Fei Liu , Yiming Yao , Ping Guo , Zhiyuan Yang , Zhe Zhao , Xi Lin , Xialiang Tong , Kun Mao , Zhichao Lu , Zhenkun Wang , Mingxuan Yuan , Qingfu Zhang

Generative Large Language Models (gLLMs), such as ChatGPT, are increasingly being used in communication research for content analysis. Studies show that gLLMs can outperform both crowd workers and trained coders, such as research…

Artificial Intelligence · Computer Science 2025-10-29 Daria Kravets-Meinke , Hannah Schmid-Petri , Sonja Niemann , Ute Schmid

Large Language Models (LLMs) have demonstrated strong capabilities in general-purpose code generation. However, generating the code which is deeply hardware-specific, architecture-aware, and performance-critical, especially for massively…

Machine Learning · Computer Science 2025-06-12 Wentao Chen , Jiace Zhu , Qi Fan , Yehan Ma , An Zou

The scientific literature's exponential growth makes it increasingly challenging to navigate and synthesize knowledge across disciplines. Large language models (LLMs) are powerful tools for understanding scientific text, but they fail to…

Computation and Language · Computer Science 2025-05-30 Abhipsha Das , Nicholas Lourie , Siavash Golkar , Mariel Pettee

The pervasive use of textual formats in the documentation of software requirements presents a great opportunity for applying large language models (LLMs) to software engineering tasks. High-quality software requirements not only enhance the…

Software Engineering · Computer Science 2024-06-18 Bingyang Wei

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs…

Large language models (LLMs) are a new and powerful tool for a wide span of applications involving natural language and demonstrate impressive code generation abilities. The goal of this work is to automatically generate tests and use these…

Artificial Intelligence · Computer Science 2024-03-12 Christian Munley , Aaron Jarmusch , Sunita Chandrasekaran

Large Language Models (LLMs) have exhibited impressive generation capabilities, but they suffer from hallucinations when solely relying on their internal knowledge, especially when answering questions that require less commonly known…

Computation and Language · Computer Science 2023-11-01 Wenting Zhao , Ye Liu , Tong Niu , Yao Wan , Philip S. Yu , Shafiq Joty , Yingbo Zhou , Semih Yavuz

Large language models (LLMs) have revolutionized code generation, automating programming with remarkable efficiency. However, these advancements challenge programming skills, ethics, and assessment integrity, making the detection of…

Computation and Language · Computer Science 2025-07-18 Daniil Orel , Dilshod Azizov , Preslav Nakov

The large set of technical documentation of legacy accelerator systems, coupled with the retirement of experienced personnel, underscores the urgent need for efficient methods to preserve and transfer specialized knowledge. This paper…

Information Retrieval · Computer Science 2025-09-03 Qing Dai , Rasmus Ischebeck , Maruisz Sapinski , Adam Grycner

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

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