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Cancer remains one of the leading causes of mortality worldwide, and among its many forms, brain tumors are particularly notorious due to their aggressive nature and the critical challenges involved in early diagnosis. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Mohammad Mahdi Danesh Pajouh

Glioblastoma (GBM) is the most common aggressive, fast-growing brain tumor, with a grim prognosis. Despite clinical diagnostic advancements, there have not been any substantial improvements to patient prognosis. Histopathological assessment…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Sanyukta Adap , Ujjwal Baid , Spyridon Bakas

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Brain tumors are one of the deadliest forms of cancer with a mortality rate of over 80%. A quick and accurate diagnosis is crucial to increase the chance of survival. However, in medical analysis, the manual annotation and segmentation of a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Zachary Schwehr , Sriman Achanta

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Background: Glioma is the most common brain malignant tumor, with a high morbidity rate and a mortality rate of more than three percent, which seriously endangers human health. The main method of acquiring brain tumors in the clinic is MRI.…

Artificial Intelligence · Computer Science 2021-07-27 Xi Guan , Guang Yang , Jianming Ye , Weiji Yang , Xiaomei Xu , Weiwei Jiang , Xiaobo Lai

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Juexin Zhang , Qifeng Zhong , Ying Weng , Ke Chen

Segmenting brain tumors in multi-parametric magnetic resonance imaging enables performing quantitative analysis in support of clinical trials and personalized patient care. This analysis provides the potential to impact clinical…

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Qifei Cui , Xinyu Lu

The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR), and the Medical Image Computing and Computer Assisted…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Ujjwal Baid , Satyam Ghodasara , Suyash Mohan , Michel Bilello , Evan Calabrese , Errol Colak , Keyvan Farahani , Jayashree Kalpathy-Cramer , Felipe C. Kitamura , Sarthak Pati , Luciano M. Prevedello , Jeffrey D. Rudie , Chiharu Sako , Russell T. Shinohara , Timothy Bergquist , Rong Chai , James Eddy , Julia Elliott , Walter Reade , Thomas Schaffter , Thomas Yu , Jiaxin Zheng , Ahmed W. Moawad , Luiz Otavio Coelho , Olivia McDonnell , Elka Miller , Fanny E. Moron , Mark C. Oswood , Robert Y. Shih , Loizos Siakallis , Yulia Bronstein , James R. Mason , Anthony F. Miller , Gagandeep Choudhary , Aanchal Agarwal , Cristina H. Besada , Jamal J. Derakhshan , Mariana C. Diogo , Daniel D. Do-Dai , Luciano Farage , John L. Go , Mohiuddin Hadi , Virginia B. Hill , Michael Iv , David Joyner , Christie Lincoln , Eyal Lotan , Asako Miyakoshi , Mariana Sanchez-Montano , Jaya Nath , Xuan V. Nguyen , Manal Nicolas-Jilwan , Johanna Ortiz Jimenez , Kerem Ozturk , Bojan D. Petrovic , Chintan Shah , Lubdha M. Shah , Manas Sharma , Onur Simsek , Achint K. Singh , Salil Soman , Volodymyr Statsevych , Brent D. Weinberg , Robert J. Young , Ichiro Ikuta , Amit K. Agarwal , Sword C. Cambron , Richard Silbergleit , Alexandru Dusoi , Alida A. Postma , Laurent Letourneau-Guillon , Gloria J. Guzman Perez-Carrillo , Atin Saha , Neetu Soni , Greg Zaharchuk , Vahe M. Zohrabian , Yingming Chen , Milos M. Cekic , Akm Rahman , Juan E. Small , Varun Sethi , Christos Davatzikos , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , John B. Freymann , Justin S. Kirby , Benedikt Wiestler , Priscila Crivellaro , Rivka R. Colen , Aikaterini Kotrotsou , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Hassan Fathallah-Shaykh , Roland Wiest , Andras Jakab , Marc-Andre Weber , Abhishek Mahajan , Bjoern Menze , Adam E. Flanders , Spyridon Bakas

Deep Learning is the state-of-the-art technology for segmenting brain tumours. However, this requires a lot of high-quality data, which is difficult to obtain, especially in the medical field. Therefore, our solutions address this problem…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 André Ferreira , Naida Solak , Jianning Li , Philipp Dammann , Jens Kleesiek , Victor Alves , Jan Egger

Gliomas, a kind of brain tumor characterized by high mortality, present substantial diagnostic challenges in low- and middle-income countries, particularly in Sub-Saharan Africa. This paper introduces a novel approach to glioma segmentation…

Accurate and automatic segmentation of brain tumors in multi-parametric magnetic resonance imaging (mpMRI) is essential for quantitative measurements, which play an increasingly important role in clinical diagnosis and prognosis. The…

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

Segmentation is a crucial task in the medical imaging field and is often an important primary step or even a prerequisite to the analysis of medical volumes. Yet treatments such as surgery complicate the accurate delineation of regions of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Heejong Kim , Leo Milecki , Mina C Moghadam , Fengbei Liu , Minh Nguyen , Eric Qiu , Abhishek Thanki , Mert R Sabuncu

Delineating the brain tumor from magnetic resonance (MR) images is critical for the treatment of gliomas. However, automatic delineation is challenging due to the complex appearance and ambiguous outlines of tumors. Considering that…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Chenyu Liu , Wangbin Ding , Lei Li , Zhen Zhang , Chenhao Pei , Liqin Huang , Xiahai Zhuang

Brain Tumor Segmentation (BraTS) plays a critical role in clinical diagnosis, treatment planning, and monitoring the progression of brain tumors. However, due to the variability in tumor appearance, size, and intensity across different MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Hongjun Zhu , Jiaohang Huang , Kuo Chen , Xuehui Ying , Ying Qian

Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard MRI. As a result, current radiotherapy planning employs a…

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histological sub-regions, i.e., peritumoral edema, necrotic core, enhancing and non-enhancing…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Marco Domenico Cirillo , David Abramian , Anders Eklund