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This paper proposes a new depression detection system based on LLMs that is both interpretable and interactive. It not only provides a diagnosis, but also diagnostic evidence and personalized recommendations based on natural language…

Computation and Language · Computer Science 2023-05-10 Wei Qin , Zetong Chen , Lei Wang , Yunshi Lan , Weijieying Ren , Richang Hong

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Dialogue State Tracking (DST) is designed to monitor the evolving dialogue state in the conversations and plays a pivotal role in developing task-oriented dialogue systems. However, obtaining the annotated data for the DST task is usually a…

Computation and Language · Computer Science 2024-05-24 Cheng Niu , Xingguang Wang , Xuxin Cheng , Juntong Song , Tong Zhang

Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding…

Computation and Language · Computer Science 2025-11-04 He Hu , Yucheng Zhou , Juzheng Si , Qianning Wang , Hengheng Zhang , Fuji Ren , Fei Ma , Laizhong Cui , Qi Tian

Mental health issues, particularly depressive disorders, present significant challenges in contemporary society, necessitating the development of effective automated diagnostic methods. This paper introduces the Agent Mental Clinic (AMC), a…

Computation and Language · Computer Science 2024-10-10 Kunyao Lan , Bingrui Jin , Zichen Zhu , Siyuan Chen , Shu Zhang , Kenny Q. Zhu , Mengyue Wu

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Depression is a serious mental illness that impacts the way people communicate, especially through their emotions, and, allegedly, the way they interact with others. This work examines depression signals in dialogs, a less studied setting…

Computation and Language · Computer Science 2022-08-23 Chuyuan Li , Chloé Braud , Maxime Amblard

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

The traditional Dialogue State Tracking (DST) problem aims to track user preferences and intents in user-agent conversations. While sufficient for task-oriented dialogue systems supporting narrow domain applications, the advent of Large…

Computation and Language · Computer Science 2023-09-19 Sarkar Snigdha Sarathi Das , Chirag Shah , Mengting Wan , Jennifer Neville , Longqi Yang , Reid Andersen , Georg Buscher , Tara Safavi

Tracking the internal states of large language models across conversations is important for safety, interpretability, and model welfare, yet current methods are limited. Linear probes and other white-box methods compress high-dimensional…

Artificial Intelligence · Computer Science 2026-04-14 Nicolas Martorell , Bruno Bianchi

Large language models (LLMs) have demonstrated notable advancements in psychological counseling. However, existing models generally do not explicitly model seekers' emotion shifts across counseling sessions, a core focus in classical…

Artificial Intelligence · Computer Science 2026-01-21 Zhentao Xia , Yongqi Fan , Yuxiang Chu , Yichao Yin , Liangliang Chen , Tong Ruan , Weiyan Zhang

Dialogue state tracking (DST) is a pivotal component in task-oriented dialogue systems. While it is relatively easy for a DST model to capture belief states in short conversations, the task of DST becomes more challenging as the length of a…

Computation and Language · Computer Science 2021-05-07 Ye Zhang , Yuan Cao , Mahdis Mahdieh , Jeffrey Zhao , Yonghui Wu

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain…

Computation and Language · Computer Science 2024-12-09 Jinpeng Hu , Tengteng Dong , Luo Gang , Hui Ma , Peng Zou , Xiao Sun , Dan Guo , Xun Yang , Meng Wang

The increasing demand for mental health services has outpaced the availability of real training data to develop clinical professionals, leading to limited support for the diagnosis of depression. This shortage has motivated the development…

Computation and Language · Computer Science 2025-08-07 Xi Wang , Anxo Perez , Javier Parapar , Fabio Crestani

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

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