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Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Multi-modal medical imaging enables comprehensive diagnostics, yet current foundation models process 2D (e.g. X-ray) and 3D (e.g. CT) data with separate, dimensionality-specific architectures. We present MultiMedVision, a unified framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Frank Li , Bardia Khosravi , Mohammadreza Chavoshi , Young Seok Jeon , Theo Dapamede , Hari Trivedi , Janice Newsome , Judy Gichoya

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

Multimodal models integrating natural language and visual information have substantially improved generalization of representation models. However, their effectiveness significantly declines in real-world situations where certain modalities…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jiajun Chen , Sai Cheng , Yutao Yuan , Yirui Zhang , Haitao Yuan , Peng Peng , Yi Zhong

Contrastive learning based vision-language joint pre-training has emerged as a successful representation learning strategy. In this paper, we present a prototype representation learning framework incorporating both global and local…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Pujin Cheng , Li Lin , Junyan Lyu , Yijin Huang , Wenhan Luo , Xiaoying Tang

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Referring Expression Comprehension (REC), which aims to ground a local visual region via natural language, is a task that heavily relies on multimodal alignment. Most existing methods utilize powerful pre-trained models to transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Ting Liu , Zunnan Xu , Yue Hu , Liangtao Shi , Zhiqiang Wang , Quanjun Yin

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Healthcare relies on multiple types of data, such as medical images, genetic information, and clinical records, to improve diagnosis and treatment. However, missing data is a common challenge due to privacy restrictions, cost, and technical…

Machine Learning · Computer Science 2025-03-13 Nazanin Moradinasab , Saurav Sengupta , Jiebei Liu , Sana Syed , Donald E. Brown

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

Machine Learning · Computer Science 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

Vision-and-language multi-modal pretraining and fine-tuning have shown great success in visual question answering (VQA). Compared to general domain VQA, the performance of biomedical VQA suffers from limited data. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Zheng Yuan , Qiao Jin , Chuanqi Tan , Zhengyun Zhao , Hongyi Yuan , Fei Huang , Songfang Huang

Multimodal representation learning has demonstrated remarkable potential in enabling models to process and integrate diverse data modalities, such as text and images, for improved understanding and performance. While the medical domain can…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Shuvendu Roy , Franklin Ogidi , Ali Etemad , Elham Dolatabadi , Arash Afkanpour

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

Modeling 3D humans accurately and robustly from a single image is very challenging, and the key for such an ill-posed problem is the 3D representation of the human models. To overcome the limitations of regular 3D representations, we…

Computer Vision and Pattern Recognition · Computer Science 2020-12-16 Zerong Zheng , Tao Yu , Yebin Liu , Qionghai Dai

Accelerating Magnetic Resonance Imaging (MRI) reduces scan time but often degrades image quality. While Implicit Neural Representations (INRs) show promise for MRI reconstruction, they struggle at high acceleration factors due to weak prior…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Ziad Al-Haj Hemidi , Eytan Kats , Mattias P. Heinrich

Harnessing the power of pre-training on large-scale datasets like ImageNet forms a fundamental building block for the progress of representation learning-driven solutions in computer vision. Medical images are inherently different from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Jeya Maria Jose Valanarasu , Yucheng Tang , Dong Yang , Ziyue Xu , Can Zhao , Wenqi Li , Vishal M. Patel , Bennett Landman , Daguang Xu , Yufan He , Vishwesh Nath

Composed image retrieval which combines a reference image and a text modifier to identify the desired target image is a challenging task, and requires the model to comprehend both vision and language modalities and their interactions.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Shu Zhao , Huijuan Xu

Multimodal learning has demonstrated incredible successes by integrating diverse data sources, yet it often relies on the availability of all modalities - an assumption that rarely holds in real-world applications. Pretrained multimodal…

Machine Learning · Computer Science 2025-04-21 Duy A. Nguyen , Quan Huu Do , Khoa D. Doan , Minh N. Do

Many healthcare applications are inherently multimodal, involving several physiological signals. As sensors for these signals become more common, improving machine learning methods for multimodal healthcare data is crucial. Pretraining…

Machine Learning · Computer Science 2024-10-23 Ching Fang , Christopher Sandino , Behrooz Mahasseni , Juri Minxha , Hadi Pouransari , Erdrin Azemi , Ali Moin , Ellen Zippi
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