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Genes, proteins and other biological entities influence one another via causal molecular networks. Causal relationships in such networks are mediated by complex and diverse mechanisms, through latent variables, and are often specific to…

Machine Learning · Computer Science 2025-03-07 Izzy Newsham , Luka Kovačević , Richard Moulange , Nan Rosemary Ke , Sach Mukherjee

With the rise of Large Language Models(LLMs), it has become crucial to understand their capabilities and limitations in deciphering and explaining the complex web of causal relationships that language entails. Current methods use either…

As the significance of understanding the cause-and-effect relationships among variables increases in the development of modern systems and algorithms, learning causality from observational data has become a preferred and efficient approach…

Machine Learning · Computer Science 2024-11-28 Xiaoxuan Li , Yao Liu , Ruoyu Wang , Lina Yao

Numerous decision-making tasks require estimating causal effects under interventions on different parts of a system. As practitioners consider using large language models (LLMs) to automate decisions, studying their causal reasoning…

Machine Learning · Computer Science 2024-12-24 Tejas Kasetty , Divyat Mahajan , Gintare Karolina Dziugaite , Alexandre Drouin , Dhanya Sridhar

Large language models (LLMs) are trained on enormous amounts of data and encode knowledge in their parameters. We propose a pipeline to elicit causal relationships from LLMs. Specifically, (i) we sample many documents from LLMs on a given…

Machine Learning · Computer Science 2026-03-05 Takashi Kameyama , Masahiro Kato , Yasuko Hio , Yasushi Takano , Naoto Minakawa

Understanding and inferring causal relationships from texts is a core aspect of human cognition and is essential for advancing large language models (LLMs) towards artificial general intelligence. Existing work evaluating LLM causal…

Artificial Intelligence · Computer Science 2026-04-14 Ryan Saklad , Aman Chadha , Oleg Pavlov , Raha Moraffah

Causal reasoning is a core component of intelligence. Large language models (LLMs) have shown impressive capabilities in generating human-like text, raising questions about whether their responses reflect true understanding or statistical…

Artificial Intelligence · Computer Science 2025-06-09 Hanna M. Dettki , Brenden M. Lake , Charley M. Wu , Bob Rehder

Large language model (LLM) development is currently driven by large-scale empirical iteration over data mixtures, reward models, routing strategies, and evaluation pipelines. Here, we argue that many central questions in LLM development and…

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

Artificial Intelligence · Computer Science 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Large language models (LLMs) have shown remarkable ability in various language tasks, especially with their emergent in-context learning capability. Extending LLMs to incorporate visual inputs, large vision-language models (LVLMs) have…

Machine Learning · Computer Science 2025-10-13 Aneesh Komanduri , Karuna Bhaila , Xintao Wu

Large language models (LLMs) exhibit remarkable capabilities on not just language tasks, but also various tasks that are not linguistic in nature, such as logical reasoning and social inference. In the human brain, neuroscience has…

Computation and Language · Computer Science 2025-02-14 Badr AlKhamissi , Greta Tuckute , Antoine Bosselut , Martin Schrimpf

Scaling laws have allowed Pre-trained Language Models (PLMs) into the field of causal reasoning. Causal reasoning of PLM relies solely on text-based descriptions, in contrast to causal discovery which aims to determine the causal…

Causal learning is the cognitive process of developing the capability of making causal inferences based on available information, often guided by normative principles. This process is prone to errors and biases, such as the illusion of…

Causal reasoning (CR) is a crucial aspect of intelligence, essential for problem-solving, decision-making, and understanding the world. While language models (LMs) can generate rationales for their outputs, their ability to reliably perform…

Artificial Intelligence · Computer Science 2025-02-19 Longxuan Yu , Delin Chen , Siheng Xiong , Qingyang Wu , Qingzhen Liu , Dawei Li , Zhikai Chen , Xiaoze Liu , Liangming Pan

The ability to understand causality significantly impacts the competence of large language models (LLMs) in output explanation and counterfactual reasoning, as causality reveals the underlying data distribution. However, the lack of a…

Machine Learning · Computer Science 2024-09-30 Yu Zhou , Xingyu Wu , Beicheng Huang , Jibin Wu , Liang Feng , Kay Chen Tan

Large Language Models (LLMs) have shown their success in language understanding and reasoning on general topics. However, their capability to perform inference based on user-specified structured data and knowledge in corpus-rare concepts,…

Computation and Language · Computer Science 2024-10-29 Haitao Jiang , Lin Ge , Yuhe Gao , Jianian Wang , Rui Song

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Large language models (LLMs) are increasingly used in domains where causal reasoning matters, yet it remains unclear whether their judgments reflect normative causal computation, human-like shortcuts, or brittle pattern matching. We…

Artificial Intelligence · Computer Science 2026-03-16 Hanna M. Dettki , Charley M. Wu , Bob Rehder

Reasoning is a fundamental aspect of human intelligence that plays a crucial role in activities such as problem solving, decision making, and critical thinking. In recent years, large language models (LLMs) have made significant progress in…

Computation and Language · Computer Science 2023-05-29 Jie Huang , Kevin Chen-Chuan Chang