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Covariate adjustment is a widely used technique in randomized clinical trials (RCTs) for improving the efficiency of treatment effect estimators. By adjusting for predictive baseline covariates, variance can be reduced, enhancing…

Methodology · Statistics 2025-10-16 Mathias Lerbech Jeppesen , Emilie Højbjerre-Frandsen

There are proposals that extend the classical generalized additive models (GAMs) to accommodate high-dimensional data ($p>>n$) using group sparse regularization. However, the sparse regularization may induce excess shrinkage when estimating…

Methodology · Statistics 2022-07-07 Boyi Guo , Byron C. Jaeger , A. K. M. Fazlur Rahman , D. Leann Long , Nengjun Yi

Generalized additive models (GAMs) are a commonly used, flexible framework applied to many problems in statistical ecology. GAMs are often considered to be a purely frequentist framework (`generalized linear models with wiggly bits'),…

Methodology · Statistics 2025-01-27 David L. Miller

We propose an extensive framework for additive regression models for correlated functional responses, allowing for multiple partially nested or crossed functional random effects with flexible correlation structures for, e.g., spatial,…

Methodology · Statistics 2013-11-26 Fabian Scheipl , Ana-Maria Staicu , Sonja Greven

The BUGS language offers a very flexible way of specifying complex statistical models for the purposes of Gibbs sampling, while its JAGS variant offers very convenient R integration via the rjags package. However, including smoothers in…

Computation · Statistics 2020-08-11 Simon N Wood

Generalized Additive Models (GAMs) are widely used explainable-by-design models in various applications. GAMs assume that the output can be represented as a sum of univariate functions, referred to as components. However, this assumption…

Machine Learning · Computer Science 2023-09-22 Vasilis Gkolemis , Anargiros Tzerefos , Theodore Dalamagas , Eirini Ntoutsi , Christos Diou

Generalized additive models (GAM) have been successfully applied to high dimensional data analysis. However, most existing methods cannot simultaneously estimate the link function, the component functions and the variable interaction. To…

Machine Learning · Statistics 2024-10-14 Peipei Yuan , Xinge You , Hong Chen , Xuelin Zhang , Qinmu Peng

Penalized quantile regression (QR) is widely used for studying the relationship between a response variable and a set of predictors under data heterogeneity in high-dimensional settings. Compared to penalized least squares, scalable…

Methodology · Statistics 2022-05-06 Rebeka Man , Xiaoou Pan , Kean Ming Tan , Wen-Xin Zhou

In developing data-driven modeling methodologies, there is an ongoing need to reconcile the strong predictive performance of opaque black-box models with the transparency required for critical applications. This work introduces an…

Machine Learning · Statistics 2026-05-21 Xin Huang , Jia Li , Jun Yu

As with the advancement of geographical information systems, non-Gaussian spatial data sets are getting larger and more diverse. This study develops a general framework for fast and flexible non-Gaussian regression, especially for…

Methodology · Statistics 2021-06-23 Daisuke Murakami , Mami Kajita , Seiji Kajita , Tomoko Matsui

Generalized additive models have been popular among statisticians and data analysts in multivariate nonparametric regression with non-Gaussian responses including binary and count data. In this paper, a new likelihood approach for fitting…

Statistics Theory · Mathematics 2008-12-18 Kyusang Yu , Byeong U. Park , Enno Mammen

Generalized Additive Models (GAMs) have quickly become the leading choice for inherently-interpretable machine learning. However, unlike uninterpretable methods such as DNNs, they lack expressive power and easy scalability, and are hence…

Machine Learning · Computer Science 2022-10-20 Abhimanyu Dubey , Filip Radenovic , Dhruv Mahajan

In many applications, linear models fit the data poorly. This article studies an appealing alternative, the generalized regression model. This model only assumes that there exists an unknown monotonically increasing link function connecting…

Methodology · Statistics 2017-07-24 Fang Han , Hongkai Ji , Zhicheng Ji , Honglang Wang

Interpretability is one of the considerations when applying machine learning to high-stakes fields such as healthcare that involve matters of life safety. Generalized Additive Models (GAMs) enhance interpretability by visualizing shape…

Machine Learning · Computer Science 2025-10-06 Fumin Wang

Partially linear additive models generalize linear ones since they model the relation between a response variable and covariates by assuming that some covariates have a linear relation with the response but each of the others enter through…

Methodology · Statistics 2023-08-08 Graciela Boente , Alejandra Mercedes Martinez

This paper presents a practical and simple fully nonparametric multivariate smoothing procedure that adapts to the underlying smoothness of the true regression function. Our estimator is easily computed by successive application of existing…

Methodology · Statistics 2011-06-08 P. A. Cornillon , N. Hengartner , E. Matzner-Løber

In other FICO Technical Papers, I have shown how to fit Generalized Additive Models (GAM) with shape constraints using quadratic programming applied to B-Spline component functions. In this paper, I extend the method to Robust Least Squares…

Methodology · Statistics 2020-03-03 Bruce Hoadley

Additive smooth models, such as Generalized additive models (GAMs) of location, scale, and shape (GAMLSS), are a popular choice for modeling experimental data. However, software available to fit such models is usually not tailored…

Methodology · Statistics 2025-06-17 Joshua Krause , Jelmer P. Borst , Jacolien van Rij

ProfileGLMM is an R package integrating Generalised Linear Mixed Models (GLMMs) as the outcome model for Bayesian profile regression. This statistical framework simultaneously i) explains the variation in the outcome and ii) clusters the…

Methodology · Statistics 2026-04-23 Matteo Amestoy , Mark A. van de Wiel , Wessel N. van Wieringen

We discuss scalar-on-function regression models where all parameters of the assumed response distribution can be modeled depending on covariates. We thus combine signal regression models with generalized additive models for location, scale…

Computation · Statistics 2016-05-16 Sarah Brockhaus , Andreas Fuest , Andreas Mayr , Sonja Greven