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Purpose: The Segment Anything Model (SAM) promises to ease the annotation bottleneck in medical segmentation, but overlapping anatomy and blurred boundaries make its point prompts ambiguous, leading to cycles of manual refinement to achieve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Adrien Meyer , Lorenzo Arboit , Giuseppe Massimiani , Shih-Min Yin , Didier Mutter , Nicolas Padoy

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

Domain adaptive segmentation (DAS) of numerous organelle instances from large-scale electron microscopy (EM) is a promising way to enable annotation-efficient learning. Inspired by SAM, we propose a promptable multitask framework, namely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Jiabao Chen , Shan Xiong , Jialin Peng

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

The Segment Anything Model (SAM) exhibits promise in generic object segmentation and offers potential for various applications. Existing methods have applied SAM to surgical instrument segmentation (SIS) by tuning SAM-based frameworks with…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Wenxi Yue , Jing Zhang , Kun Hu , Qiuxia Wu , Zongyuan Ge , Yong Xia , Jiebo Luo , Zhiyong Wang

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Deep learning models trained with large amounts of data have become a recent and effective approach to predictive problem solving -- these have become known as "foundation models" as they can be used as fundamental tools for other…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 José Guilherme de Almeida , Nuno M. Rodrigues , Sara Silva , Nickolas Papanikolaou

The Segment Anything Model (SAM), originally designed for general-purpose segmentation tasks, has been used recently for polyp segmentation. Nonetheless, fine-tuning SAM with data from new imaging centers or clinics poses significant…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Md Mostafijur Rahman , Mustafa Munir , Debesh Jha , Ulas Bagci , Radu Marculescu

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

We present Segment Anything Model (SAM) 3, a unified model that detects, segments, and tracks objects in images and videos based on concept prompts, which we define as either short noun phrases (e.g., "yellow school bus"), image exemplars,…

Open-set image segmentation poses a significant challenge because existing methods often demand extensive training or fine-tuning and generally struggle to segment unified objects consistently across diverse text reference expressions.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Zhihua Liu , Amrutha Saseendran , Lei Tong , Xilin He , Fariba Yousefi , Nikolay Burlutskiy , Dino Oglic , Tom Diethe , Philip Teare , Huiyu Zhou , Chen Jin

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

The Segment Anything Model (SAM), a foundational model designed for promptable segmentation tasks, demonstrates exceptional generalization capabilities, making it highly promising for natural scene image segmentation. However, SAM's lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Linghao Zheng , Xinyang Pu , Feng Xu

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Medical image segmentation is a vital healthcare endeavor requiring precise and efficient models for appropriate diagnosis and treatment. Vision transformer (ViT)-based segmentation models have shown great performance in accomplishing this…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Numan Saeed , Muhammad Ridzuan , Roba Al Majzoub , Mohammad Yaqub

The Segment Anything Model (SAM) has revolutionized interactive segmentation through spatial prompting. While existing work primarily focuses on automating prompts in various settings, real-world annotation workflows involve iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib

The Segment Anything Model (SAM) is a recently developed large model for general-purpose segmentation for computer vision tasks. SAM was trained using 11 million images with over 1 billion masks and can produce segmentation results for a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Yizhe Zhang , Tao Zhou , Shuo Wang , Peixian Liang , Danny Z. Chen

Segment anything model (SAM) has shown its spectacular performance in segmenting universal objects, especially when elaborate prompts are provided. However, the drawback of SAM is twofold. On the first hand, it fails to segment specific…

Computer Vision and Pattern Recognition · Computer Science 2023-11-16 Leiping Jie , Hui Zhang

Segment Anything Model (SAM) has gained significant attention because of its ability to segment various objects in images given a prompt. The recently developed SAM 2 has extended this ability to video inputs. This opens an opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Haoyu Dong , Hanxue Gu , Yaqian Chen , Jichen Yang , Yuwen Chen , Maciej A. Mazurowski

Recently, promptable segmentation models, such as the Segment Anything Model (SAM), have demonstrated robust zero-shot generalization capabilities on static images. These promptable models exhibit denoising abilities for imprecise prompt…

Computer Vision and Pattern Recognition · Computer Science 2024-03-08 Tao Zhou , Wenhan Luo , Qi Ye , Zhiguo Shi , Jiming Chen
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