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The Segment Anything Model (SAM), developed by Meta AI Research, represents a significant breakthrough in computer vision, offering a robust framework for image and video segmentation. This survey provides a comprehensive exploration of the…

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

The Segment Anything Model (SAM) is a powerful foundation model for image segmentation, showing robust zero-shot generalization through prompt engineering. However, relying on manual prompts is impractical for real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yi Chen , Mu-Young Son , Chuanbo Hua , Joo-Young Kim

The Segment Anything Model (SAM) has revolutionized image segmentation through its innovative prompt-based approach, yet the critical role of prompt engineering in its success remains underexplored. This paper presents the first…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Yidong Jiang

Promptable foundation models such as the Segment Anything Model (SAM) produce high-quality masks but remain semantically blind, relying on external prompts to specify categories. Existing vision-language approaches address this limitation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Shayan Jalilian , Abdul Bais

Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

In the rapidly evolving field of AI research, foundational models like BERT and GPT have significantly advanced language and vision tasks. The advent of pretrain-prompting models such as ChatGPT and Segmentation Anything Model (SAM) has…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Saiyang Na , Yuzhi Guo , Feng Jiang , Hehuan Ma , Junzhou Huang

Image segmentation is a critical task in microscopy, essential for accurately analyzing and interpreting complex visual data. This task can be performed using custom models trained on domain-specific datasets, transfer learning from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Kamyar Barakati , Utkarsh Pratiush , Sheryl L. Sanchez , Aditya Raghavan , Delia J. Milliron , Mahshid Ahmadi , Philip D. Rack , Sergei V. Kalinin

The Segment Anything Model (SAM) has demonstrated impressive generalization in prompt-based segmentation. Yet, the potential of semantic text prompts remains underexplored compared to traditional spatial prompts like points and boxes. This…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Shayan Jalilian , Abdul Bais

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

The Segment Anything Model (SAM) is a powerful foundation model that has revolutionised image segmentation. To apply SAM to surgical instrument segmentation, a common approach is to locate precise points or boxes of instruments and then use…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenxi Yue , Jing Zhang , Kun Hu , Yong Xia , Jiebo Luo , Zhiyong Wang

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

The Segment Anything Model (SAM) is a deep neural network foundational model designed to perform instance segmentation which has gained significant popularity given its zero-shot segmentation ability. SAM operates by generating masks based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yona Falinie A. Gaus , Neelanjan Bhowmik , Brian K. S. Isaac-Medina , Toby P. Breckon

The recently introduced Segment Anything Model (SAM), a Visual Foundation Model (VFM), has demonstrated impressive capabilities in zero-shot segmentation tasks across diverse natural image datasets. Despite its success, SAM encounters…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Chunpeng Zhou , Kangjie Ning , Qianqian Shen , Sheng Zhou , Zhi Yu , Haishuai Wang

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

The Segment Anything Model (SAM) achieves remarkable promptable segmentation given high-quality prompts which, however, often require good skills to specify. To make SAM robust to casual prompts, this paper presents the first comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Qi Fan , Xin Tao , Lei Ke , Mingqiao Ye , Yuan Zhang , Pengfei Wan , Zhongyuan Wang , Yu-Wing Tai , Chi-Keung Tang

The recent Segment Anything Models (SAMs) have emerged as foundational visual models for general interactive segmentation. Despite demonstrating robust generalization abilities, they still suffer performance degradations in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuan Yao , Qiushi Yang , Miaomiao Cui , Liefeng Bo