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The adaptive immune system recognizes antigens via an immense array of antigen-binding antibodies and T-cell receptors, the immune repertoire. The interrogation of immune repertoires is of high relevance for understanding the adaptive…

Quantitative Methods · Quantitative Biology 2018-03-02 Enkelejda Miho , Alexander Yermanos , Cédric R. Weber , Christoph T. Berger , Sai T. Reddy , Victor Greiff

This paper presents a hybrid system for intuitive item similarity search that combines a Large Language Model (LLM) with a custom K-Nearest Neighbors (KNN) algorithm. Unlike black-box dense vector systems, this architecture provides…

Information Retrieval · Computer Science 2025-09-29 Ana Rodrigues , João Mata , Rui Rego

A similarity join aims to find all similar pairs between two collections of records. Established approaches usually deal with synthetic differences like typos and abbreviations, but neglect the semantic relations between words. Such…

Information Retrieval · Computer Science 2018-10-30 Pengfei Xu , Jiaheng Lu

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

Genomics · Quantitative Biology 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

Nearest Neighbor Search (NNS) has recently drawn a rapid increase of interest due to its core role in managing high-dimensional vector data in data science and AI applications. The interest is fueled by the success of neural embedding,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-01 Zhen Peng , Minjia Zhang , Kai Li , Ruoming Jin , Bin Ren

Protein similarity searches are a routine job for molecular biologists where a query sequence of amino acids needs to be compared and ranked against an ever-growing database of proteins. All available algorithms in this field can be grouped…

Computational Engineering, Finance, and Science · Computer Science 2015-08-27 Akash Nag , Sunil Karforma

This work presents an adaptive group testing framework for the range-based high dimensional near neighbor search problem. Our method efficiently marks each item in a database as neighbor or non-neighbor of a query point, based on a cosine…

Data Structures and Algorithms · Computer Science 2024-09-10 Harsh Shah , Kashish Mittal , Ajit Rajwade

State-of-the-art hierarchical localisation pipelines (HLoc) employ image retrieval (IR) to establish 2D-3D correspondences by selecting the top-$k$ most similar images from a reference database. While increasing $k$ improves localisation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Changkun Liu , Jianhao Jiao , Huajian Huang , Zhengyang Ma , Dimitrios Kanoulas , Tristan Braud

We study the Approximate Nearest Neighbor (ANN) problem under a powerful adaptive adversary that controls both the dataset and a sequence of $Q$ queries. Primarily, for the high-dimensional regime of $d = \omega(\sqrt{Q})$, we introduce a…

Data Structures and Algorithms · Computer Science 2026-01-05 Alexandr Andoni , Themistoklis Haris , Esty Kelman , Krzysztof Onak

Neighbor search is of fundamental important to many engineering and science fields such as physics simulation and computer graphics. This paper proposes to formulate neighbor search as a ray tracing problem and leverage the dedicated ray…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-10 Yuhao Zhu

Similarity search is a key to a variety of applications including content-based search for images and video, recommendation systems, data deduplication, natural language processing, computer vision, databases, computational biology, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-07-11 Vincent T. Lee , Amrita Mazumdar , Carlo C. del Mundo , Armin Alaghi , Luis Ceze , Mark Oskin

We develop methods for accelerating metric similarity search that are effective on modern hardware. Our algorithms factor into easily parallelizable components, making them simple to deploy and efficient on multicore CPUs and GPUs. Despite…

Databases · Computer Science 2016-11-15 Lawrence Cayton

With the growing integration of structured and unstructured data, new methods have emerged for performing similarity searches on vectors while honoring structured attribute constraints, i.e., a process known as Filtering Approximate Nearest…

Databases · Computer Science 2025-09-23 Mocheng Li , Xiao Yan , Baotong Lu , Yue Zhang , James Cheng , Chenhao Ma

Research on nearest-neighbor methods tends to focus somewhat dichotomously either on the statistical or the computational aspects -- either on, say, Bayes consistency and rates of convergence or on techniques for speeding up the proximity…

Statistics Theory · Mathematics 2020-04-17 Klim Efremenko , Aryeh Kontorovich , Moshe Noivirt

High-dimensional similarity search underpins modern retrieval systems, yet uniform search strategies fail to exploit the heterogeneous nature of real-world query distributions. We present an adaptive prefiltering framework that leverages…

Information Retrieval · Computer Science 2026-02-27 Teodor-Ioan Calin

We present an I/O-efficient algorithm for computing similarity joins based on locality-sensitive hashing (LSH). In contrast to the filtering methods commonly suggested our method has provable sub-quadratic dependency on the data size.…

Data Structures and Algorithms · Computer Science 2017-03-29 Rasmus Pagh , Ninh Pham , Francesco Silvestri , Morten Stöckel

Integer Linear Programs (ILPs) are powerful tools for modeling and solving a large number of combinatorial optimization problems. Recently, it has been shown that Large Neighborhood Search (LNS), as a heuristic algorithm, can find high…

Artificial Intelligence · Computer Science 2024-01-17 Taoan Huang , Aaron Ferber , Yuandong Tian , Bistra Dilkina , Benoit Steiner

We present a new algorithm for the approximate near neighbor problem that combines classical ideas from group testing with locality-sensitive hashing (LSH). We reduce the near neighbor search problem to a group testing problem by…

Data Structures and Algorithms · Computer Science 2021-06-23 Joshua Engels , Benjamin Coleman , Anshumali Shrivastava

Nowadays, subsequence similarity search is required in a wide range of time series mining applications: climate modeling, financial forecasts, medical research, etc. In most of these applications, the Dynamic TimeWarping (DTW) similarity…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-09 Yana Kraeva , Mikhail Zymbler
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