English
Related papers

Related papers: scVGAE: A Novel Approach using ZINB-Based Variatio…

200 papers

This paper looks into the problem of detecting network anomalies by analyzing NetFlow records. While many previous works have used statistical models and machine learning techniques in a supervised way, such solutions have the limitations…

Machine Learning · Computer Science 2019-03-18 Quoc Phong Nguyen , Kar Wai Lim , Dinil Mon Divakaran , Kian Hsiang Low , Mun Choon Chan

Single-cell RNA sequencing (scRNA-seq) has the potential to provide powerful, high-resolution signatures to inform disease prognosis and precision medicine. This paper takes an important first step towards this goal by developing an…

Quantitative Methods · Quantitative Biology 2021-10-15 Bryan He , Matthew Thomson , Meena Subramaniam , Richard Perez , Chun Jimmie Ye , James Zou

Semi-implicit graph variational auto-encoder (SIG-VAE) is proposed to expand the flexibility of variational graph auto-encoders (VGAE) to model graph data. SIG-VAE employs a hierarchical variational framework to enable neighboring node…

Machine Learning · Computer Science 2020-04-23 Arman Hasanzadeh , Ehsan Hajiramezanali , Nick Duffield , Krishna R. Narayanan , Mingyuan Zhou , Xiaoning Qian

Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields valuable insights about gene expression profiles for…

Applications · Statistics 2019-04-16 Lingxue Zhu , Jing Lei , Bernie Devlin , Kathryn Roeder

Structured variational autoencoders (SVAEs) combine probabilistic graphical model priors on latent variables, deep neural networks to link latent variables to observed data, and structure-exploiting algorithms for approximate posterior…

Machine Learning · Statistics 2023-05-29 Yixiu Zhao , Scott W. Linderman

Learning interpretable representations of data remains a central challenge in deep learning. When training a deep generative model, the observed data are often associated with certain categorical labels, and, in parallel with learning to…

Machine Learning · Computer Science 2019-10-01 Yifan Xue , Michael Ding , Xinghua Lu

View synthesis aims to produce unseen views from a set of views captured by two or more cameras at different positions. This task is non-trivial since it is hard to conduct pixel-level matching among different views. To address this issue,…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Zhuoman Liu , Wei Jia , Ming Yang , Peiyao Luo , Yong Guo , Mingkui Tan

Class imbalance in graph data presents significant challenges for node classification. While existing methods, such as SMOTE-based approaches, partially mitigate this issue, they still exhibit limitations in constructing imbalanced graphs.…

Machine Learning · Computer Science 2024-03-28 Yulan Hu , Sheng Ouyang , Zhirui Yang , Yong Liu

Humans are able to identify and categorize novel compositions of known concepts. The task in Compositional Zero-Shot learning (CZSL) is to learn composition of primitive concepts, i.e. objects and states, in such a way that even their novel…

Computer Vision and Pattern Recognition · Computer Science 2022-04-27 Muhammad Umer Anwaar , Zhihui Pan , Martin Kleinsteuber

Graph autoencoders (GAE) and variational graph autoencoders (VGAE) emerged as two powerful groups of unsupervised node embedding methods, with various applications to graph-based machine learning problems such as link prediction and…

Machine Learning · Computer Science 2025-06-19 Guillaume Salha-Galvan

Multiple modalities often co-occur when describing natural phenomena. Learning a joint representation of these modalities should yield deeper and more useful representations. Previous generative approaches to multi-modal input either do not…

Machine Learning · Computer Science 2018-11-13 Mike Wu , Noah Goodman

In Fine-Grained Visual Classification (FGVC), distinguishing highly similar subcategories remains a formidable challenge, often necessitating datasets with extensive variability. The acquisition and annotation of such FGVC datasets are…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Qiyu Liao , Xin Yuan , Min Xu , Dadong Wang

Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular processes by enabling gene expression analysis at the individual cell level. Clustering allows for the identification of cell types and the further…

Machine Learning · Computer Science 2025-06-03 Ziwen Wang

Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

Background: Advances in high throughput sequencing technologies provide a huge number of genomes to be analyzed. Thus, computational methods play a crucial role in analyzing and extracting knowledge from the data generated. Investigating…

As a powerful tool for characterizing cellular subpopulations and cellular heterogeneity, single cell RNA sequencing (scRNA-seq) technology offers advantages of high throughput and multidimensional analysis. However, the process of data…

Machine Learning · Computer Science 2024-11-19 Zhuorui Cui , Shengze Dong , Ding Liu

Generating high-fidelity and biologically plausible synthetic single-cell RNA sequencing (scRNA-seq) data, especially with conditional control, is challenging due to its high dimensionality, sparsity, and complex biological variations.…

Machine Learning · Computer Science 2025-06-17 Lorenzo Bini , Stephane Marchand-Maillet

Scene Graph Generation (SGG) aims to extract entities, predicates and their semantic structure from images, enabling deep understanding of visual content, with many applications such as visual reasoning and image retrieval. Nevertheless,…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Alireza Zareian , Svebor Karaman , Shih-Fu Chang

Single-cell RNA sequencing (scRNA-seq) provides a high throughput, quantitative and unbiased framework for scientists in many research fields to identify and characterize cell types within heterogeneous cell populations from various…

Quantitative Methods · Quantitative Biology 2022-09-28 Yeganeh Madadi , Aboozar Monavarfeshani , Hao Chen , W. Daniel Stamer , Robert W. Williams , Siamak Yousefi

scRNA-seq clustering is a critical task for analyzing single-cell RNA sequencing (scRNA-seq) data, as it groups cells with similar gene expression profiles. Transformers, as powerful foundational models, have been applied to scRNA-seq…

Machine Learning · Computer Science 2026-02-10 Zhuomin Liang , Liang Bai , Xian Yang