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We demonstrate the feasibility of high-quality digital holography of the human retina in real-time with a fast camera and commodity computer hardware. High throughput rendering of digital Fresnel holograms from optically-acquired inline…

Medical Physics · Physics 2020-04-03 Leo Puyo , Loic Bellonnet-Mottet , Antoine Martin , Francois Te , Michel Paques , Michael Atlan

Holography is an optical technique enabling to record phase objects. Holographic interferometry uses this faculty to make a phase object interfere with a memory of itself at a preceding time, recorded on a hologram. Interference fringes…

Fluid Dynamics · Physics 2009-11-23 Jean Colombani , Jacques Bert

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

Intravital microscopy is an essential tool that reveals behaviours of live cells under conditions close to natural physiological states. So far, although various approaches for imaging cells in vivo have been proposed, most require the use…

Biological Physics · Physics 2016-07-04 Kyoohyun Kim , Kibaek Choe , Inwon Park , Pilhan Kim , YongKeun Park

Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging modality for visualization of retinal blood flow in the human retina. Using specific OCTA imaging biomarkers for the identification of pathologies, automated…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Anna Breger , Felix Goldbach , Bianca S. Gerendas , Ursula Schmidt-Erfurth , Martin Ehler

Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…

Medical Physics · Physics 2020-07-13 Pedro Mecê , Elena Gofas-Salas , Michel Paques , Kate Grieve , Serge Meimon

There has been a consistent growth in research involving imaging of microvasculature over the past few decades. By 2008, publications mentioning the microcirculation had grown more than 2000 per annum. Many techniques have been demonstrated…

Medical Physics · Physics 2019-07-04 Cerine Lal , Martin J Leahy

Corneal evaluation in ophthalmology necessitates cellular-resolution and fast imaging techniques allowing accurate diagnoses. Currently, the fastest volumetric imaging technique is Fourier-domain full-field optical coherence tomography…

Holography is a vital tool used in various applications from microscopy, solar energy, imaging, display to information encryption. Generation of a holographic image and reconstruction of object/hologram information from a holographic image…

Optics · Physics 2021-05-28 Alim Yolalmaz , Emre Yüce

A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin…

Medical Physics · Physics 2017-12-04 Chris Wu , Tanay Tandon

Color Doppler echocardiography enables visualization of blood flow within the heart. However, the limited frame rate impedes the quantitative assessment of blood velocity throughout the cardiac cycle, thereby compromising a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Julia Puig , Denis Friboulet , Hang Jung Ling , François Varray , Jonathan Porée , Jean Provost , Damien Garcia , Fabien Millioz

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Optical coherence tomography angiography (OCTA) has been established as a powerful tool for investigating vascular diseases and is expected to become a standard of care technology. However, its widespread clinical usage is hindered by…

Medical Physics · Physics 2021-09-10 Si Chen , Kan Lin , Linbo Liu

With the advent of smartphone indirect ophthalmoscopy, teleophthalmology - the use of specialist ophthalmology assets at a distance from the patient - has experienced a breakthrough, promising enormous benefits especially for healthcare in…

Computer Vision and Pattern Recognition · Computer Science 2019-03-08 Chris von Csefalvay

Retinal Optical Coherence Tomography (OCT), a noninvasive cross-sectional scan of the eye with qualitative 3D visualization of the retinal anatomy is use to study the retinal structure and the presence of pathogens. The advent of the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with blood flow far exceeding that of the brain and kidney. Thus, there has been growing interest…

Image and Video Processing · Electrical Eng. & Systems 2025-02-12 Jamie Burke

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Doppler orbitography uses the Doppler shift in a transmitted signal to determine the orbital parameters of satellites including range and range-rate (or radial velocity). We describe two techniques for atmospheric-limited optical Doppler…

Instrumentation and Methods for Astrophysics · Physics 2020-06-09 Benjamin P. Dix-Matthews , Sascha W. Schediwy , David R. Gozzard , Simon Driver , Karl Ulrich Schreibe , Randall Carman , Michael Tobar

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

The emergence of artificial intelligence (AI), particularly deep learning (DL), has marked a new era in the realm of ophthalmology, offering transformative potential for the diagnosis and treatment of posterior segment eye diseases. This…

Image and Video Processing · Electrical Eng. & Systems 2025-01-09 Duy M. H. Nguyen , Hasan Md Tusfiqur Alam , Tai Nguyen , Devansh Srivastav , Hans-Juergen Profitlich , Ngan Le , Daniel Sonntag