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We present the first diffusion-based framework that can learn an unknown distribution using only highly-corrupted samples. This problem arises in scientific applications where access to uncorrupted samples is impossible or expensive to…

Machine Learning · Computer Science 2023-05-31 Giannis Daras , Kulin Shah , Yuval Dagan , Aravind Gollakota , Alexandros G. Dimakis , Adam Klivans

We present the first framework to solve linear inverse problems leveraging pre-trained latent diffusion models. Previously proposed algorithms (such as DPS and DDRM) only apply to pixel-space diffusion models. We theoretically analyze our…

Machine Learning · Computer Science 2023-07-04 Litu Rout , Negin Raoof , Giannis Daras , Constantine Caramanis , Alexandros G. Dimakis , Sanjay Shakkottai

Inverse problems are fundamental to science and engineering, where the goal is to infer an underlying signal or state from incomplete or noisy measurements. Recent approaches employ diffusion models as powerful implicit priors for such…

Machine Learning · Computer Science 2025-11-27 Bilal Ahmed , Joseph G. Makin

We propose Amortized Posterior Sampling (APS), a novel variational inference approach for efficient posterior sampling in inverse problems. Our method trains a conditional flow model to minimize the divergence between the variational…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Abbas Mammadov , Hyungjin Chung , Jong Chul Ye

Image restoration aims to recover high-quality images from degraded observations. When the degradation process is known, the recovery problem can be formulated as an inverse problem, and in a Bayesian context, the goal is to sample a clean…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Darshan Thaker , Abhishek Goyal , René Vidal

Diffusion models have emerged as a powerful foundation model for visual generations. With an appropriate sampling process, it can effectively serve as a generative prior for solving general inverse problems. Current posterior sampling-based…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Shijie Zhou , Huaisheng Zhu , Rohan Sharma , Jiayi Chen , Ruiyi Zhang , Kaiyi Ji , Changyou Chen

Inverse problems, where the goal is to recover an unknown signal from noisy or incomplete measurements, are central to applications in medical imaging, remote sensing, and computational biology. Diffusion models have recently emerged as…

Machine Learning · Computer Science 2026-01-15 Shayan Mohajer Hamidi , En-Hui Yang , Ben Liang

With the rapid development of diffusion models and flow-based generative models, there has been a surge of interests in solving noisy linear inverse problems, e.g., super-resolution, deblurring, denoising, colorization, etc, with generative…

Machine Learning · Computer Science 2024-10-22 Xiangming Meng , Yoshiyuki Kabashima

Inverse problems exist in many disciplines of science and engineering. In computer vision, for example, tasks such as inpainting, deblurring, and super resolution can be effectively modeled as inverse problems. Recently, denoising diffusion…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Shayan Mohajer Hamidi , En-Hui Yang

Diffusion models (DMs) have emerged as powerful generative models for solving inverse problems, offering a good approximation of prior distributions of real-world image data. Typically, diffusion models rely on large-scale clean signals to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Yifei Wang , Weimin Bai , Weijian Luo , Wenzheng Chen , He Sun

Diffusion models have been recently studied as powerful generative inverse problem solvers, owing to their high quality reconstructions and the ease of combining existing iterative solvers. However, most works focus on solving simple linear…

Machine Learning · Statistics 2025-10-06 Hyungjin Chung , Jeongsol Kim , Michael T. Mccann , Marc L. Klasky , Jong Chul Ye

Recent studies demonstrate that diffusion models can serve as a strong prior for solving inverse problems. A prominent example is Diffusion Posterior Sampling (DPS), which approximates the posterior distribution of data given the measure…

Machine Learning · Statistics 2024-09-16 Yaxuan Zhu , Zehao Dou , Haoxin Zheng , Yasi Zhang , Ying Nian Wu , Ruiqi Gao

Deep generative models have emerged as state-of-the-art for solving inverse problems, but applying them to inverse problems for PDEs, like electrical impedance tomography (EIT) remains challenging. Because physical domains are naturally…

Image and Video Processing · Electrical Eng. & Systems 2026-05-20 Giovanni S. Alberti , Damiana Lazzaro , Serena Morigi , Matteo Santacesaria , Shibo Wang

Inverse problems arise in a multitude of applications, where the goal is to recover a clean signal from noisy and possibly (non)linear observations. The difficulty of a reconstruction problem depends on multiple factors, such as the ground…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

We propose a data-efficient, physics-aware generative framework in function space for inverse PDE problems. Existing plug-and-play diffusion posterior samplers represent physics implicitly through joint coefficient-solution modeling,…

Machine Learning · Computer Science 2026-03-03 Thomas Y. L. Lin , Jiachen Yao , Lufang Chiang , Julius Berner , Anima Anandkumar

Reconstruction-based methods have been commonly used for unsupervised anomaly detection, in which a normal image is reconstructed and compared with the given test image to detect and locate anomalies. Recently, diffusion models have shown…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Di Wu , Shicai Fan , Xue Zhou , Li Yu , Yuzhong Deng , Jianxiao Zou , Baihong Lin

Unified image restoration is a significantly challenging task in low-level vision. Existing methods either make tailored designs for specific tasks, limiting their generalizability across various types of degradation, or rely on training…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Huaqiu Li , Yong Wang , Tongwen Huang , Hailang Huang , Haoqian Wang , Xiangxiang Chu

Purpose: The Unadjusted Langevin Algorithm (ULA) in combination with diffusion models can generate high quality MRI reconstructions with uncertainty estimation from highly undersampled k-space data. However, sampling methods such as…

Medical Physics · Physics 2026-05-26 Moritz Blumenthal , Tina Holliber , Jonathan I. Tamir , Martin Uecker

While continuous diffusion models have achieved remarkable success, discrete diffusion offers a unified framework for jointly modeling text and images. Beyond unification, discrete diffusion provides faster inference, finer control, and…

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