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In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

In order to improve image quality of projection in industrial applications, generally, a standard method is to increase the current or exposure time, which might cause overexposure of detector units in areas of thin objects or backgrounds.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mengyu Sun , Dimeng Xia , Shusen Zhao , Weibin Zhang , Yaobin He

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Felix Thomsen , José M. Fuertes García , Manuel Lucena , Juan Pisula , Rodrigo de Luis García , Jan Broggrefe , Claudio Delrieux

Low-dose computed tomography (CT) represents a significant improvement in patient safety through lower radiation doses, but increased noise, blur, and contrast loss can diminish diagnostic quality. Therefore, consistency and robustness in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Kagan Celik , Mehmet Ozan Unal , Metin Ertas , Isa Yildirim

As the medical usage of computed tomography (CT) continues to grow, the radiation dose should remain at a low level to reduce the health risks. Therefore, there is an increasing need for algorithms that can reconstruct high-quality images…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Davood Karimi , Rabab K. Ward

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

While compressed sensing (CS) based reconstructions have been developed for low-dose CBCT, a clear understanding on the relationship between the image quality and imaging dose at low dose levels is needed. In this paper, we qualitatively…

Medical Physics · Physics 2015-06-03 Hao Yan , Laura Cervino , Xun Jia , Steve B. Jiang

Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…

Owing to recent advances in thoracic electrical impedance tomography, a patient's hemodynamic function can be noninvasively and continuously estimated in real-time by surveilling a cardiac volume signal associated with stroke volume and…

Signal Processing · Electrical Eng. & Systems 2023-01-05 Chang Min Hyun , Tae Jun Jang , Jeongchan Nam , Hyeuknam Kwon , Kiwan Jeon , Kyunghun Lee

Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…

Quantitative Methods · Quantitative Biology 2014-05-28 Kevin J. Black , Jonathan M. Koller , Brad D. Miller

Focused transmits are the most commonly used transmit strategy for echocardiograms, but suffer from relatively low frame rates, and in 3D, even lower volume rates. Fast imaging based on unfocused transmits has disadvantages such as motion…

Signal Processing · Electrical Eng. & Systems 2026-05-14 Wessel L. van Nierop , Oisín Nolan , Tristan S. W. Stevens , Ruud J. G. van Sloun

In order to reduce the potential radiation risk, low-dose CT has attracted more and more attention. However, simply lowering the radiation dose will significantly degrade the imaging quality. In this paper, we propose a noise reduction…

Medical Physics · Physics 2016-09-28 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

We propose a Noise Entangled GAN (NE-GAN) for simulating low-dose computed tomography (CT) images from a higher dose CT image. First, we present two schemes to generate a clean CT image and a noise image from the high-dose CT image. Then,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-22 Chuang Niu , Ge Wang , Pingkun Yan , Juergen Hahn , Youfang Lai , Xun Jia , Arjun Krishna , Klaus Mueller , Andreu Badal , KyleJ. Myers , Rongping Zeng

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been…

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

CT protocol design and quality control would benefit from automated tools to estimate the quality of generated CT images. These tools could be used to identify erroneous CT acquisitions or refine protocols to achieve certain signal to noise…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Sohini Roychowdhury , Nathan Hollraft , Adam Alessio

Computed tomography (CT) is routinely used for three-dimensional non-invasive imaging. Numerous data-driven image denoising algorithms were proposed to restore image quality in low-dose acquisitions. However, considerably less research…

Objectives: Analyze the types of studies and algorithms that are most applied, Identify the anatomical regions treated. Determine the application of parallel techniques used in studies carried out between 2010 and 2022 in research on noise…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Sussana M. Florez-Aroni , Mijail A. Hancco-Condori , Fred Torres-Cruz

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang
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