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Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Adversarial purification with diffusion models seeks to project adversarial examples back toward the data manifold, but balancing semantic preservation and robustness against adaptive attacks remains challenging. Recent work shows that…

Machine Learning · Computer Science 2026-05-12 Daniel Wesego , Pedram Rooshenas

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…

Generative models have demonstrated significant success in anomaly detection and segmentation over the past decade. Recently, diffusion models have emerged as a powerful alternative, outperforming previous approaches such as GANs and VAEs.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Mehrdad Moradi , Marco Grasso , Bianca Maria Colosimo , Kamran Paynabar

Denoising diffusion models have recently achieved remarkable success in image generation, capturing rich information about natural image statistics. This makes them highly promising for image reconstruction, where the goal is to recover a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Shady Abu-Hussein , Tom Tirer , Raja Giryes

Diffusion models have shown superior performance on unsupervised anomaly detection tasks. Since trained with normal data only, diffusion models tend to reconstruct normal counterparts of test images with certain noises added. However, these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hang Yao , Ming Liu , Haolin Wang , Zhicun Yin , Zifei Yan , Xiaopeng Hong , Wangmeng Zuo

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Thermal infrared imaging exhibits considerable potentials for robotic perception tasks, especially in environments with poor visibility or challenging lighting conditions. However, TIR images typically suffer from heavy non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Tai Hyoung Rhee , Dong-guw Lee , Ayoung Kim

Reconstructing high-fidelity magnetic resonance (MR) images from under-sampled k-space is a commonly used strategy to reduce scan time. The posterior sampling of diffusion models based on the real measurement data holds significant promise…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Jiayue Chu , Chenhe Du , Xiyue Lin , Yuyao Zhang , Hongjiang Wei

Deep learning-based diagnostic systems have demonstrated potential in skin disease diagnosis. However, their performance can easily degrade on test domains due to distribution shifts caused by input-level corruptions, such as imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-05-21 Ming Hu , Siyuan Yan , Peng Xia , Feilong Tang , Wenxue Li , Peibo Duan , Lin Zhang , Zongyuan Ge

Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Tianyu Han , Sven Nebelung , Firas Khader , Jakob Nikolas Kather , Daniel Truhn

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

Medical Physics · Physics 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Diffusion models have established new state of the art in a multitude of computer vision tasks, including image restoration. Diffusion-based inverse problem solvers generate reconstructions of exceptional visual quality from heavily…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

This paper explores the utility of diffusion-based models for anomaly detection, focusing on their efficacy in identifying deviations in both compact and high-resolution datasets. Diffusion-based architectures, including Denoising Diffusion…

Machine Learning · Computer Science 2024-12-11 Aryan Bhosale , Samrat Mukherjee , Biplab Banerjee , Fabio Cuzzolin

Image restoration aims to recover degraded images. However, existing diffusion-based restoration methods, despite great success in natural image restoration, often struggle to faithfully reconstruct textual regions in degraded images. Those…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Jaewon Min , Jin Hyeon Kim , Paul Hyunbin Cho , Jaeeun Lee , Jihye Park , Minkyu Park , Sangpil Kim , Hyunhee Park , Seungryong Kim
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