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AI for cancer detection encounters the bottleneck of data scarcity, annotation difficulty, and low prevalence of early tumors. Tumor synthesis seeks to create artificial tumors in medical images, which can greatly diversify the data and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Yuxiang Lai , Xiaoxi Chen , Angtian Wang , Alan Yuille , Zongwei Zhou

Computed tomography (CT) has become an essential part of modern science and medicine. A CT scanner consists of an X-ray source that is spun around an object of interest. On the opposite end of the X-ray source, a detector captures X-rays…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Thomas Germer , Jan Robine , Sebastian Konietzny , Stefan Harmeling , Tobias Uelwer

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

Medical Physics · Physics 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

To achieve magnetic resonance (MR)-only radiotherapy, a method needs to be employed to estimate a synthetic CT (sCT) for generating electron density maps and patient positioning reference images. We investigated 2D and 3D convolutional…

Medical Physics · Physics 2019-08-06 Jie Fu , Yingli Yang , Kamal Singhrao , Dan Ruan , Daniel A. Low , John H. Lewis

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

This paper newly introduces multi-modality loss function for GAN-based super-resolution that can maintain image structure and intensity on unpaired training dataset of clinical CT and micro CT volumes. Precise non-invasive diagnosis of lung…

Image and Video Processing · Electrical Eng. & Systems 2020-04-08 Tong Zheng , Hirohisa Oda , Takayasu Moriya , Shota Nakamura , Masahiro Oda , Masaki Mori , Horitsugu Takabatake , Hiroshi Natori , Kensaku Mori

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

A key challenge for the development and deployment of artificial intelligence (AI) solutions in radiology is solving the associated data limitations. Obtaining sufficient and representative patient datasets with appropriate annotations may…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Elena Sizikova , Andreu Badal , Jana G. Delfino , Miguel Lago , Brandon Nelson , Niloufar Saharkhiz , Berkman Sahiner , Ghada Zamzmi , Aldo Badano

Generative augmentation is often proposed as a remedy for small medical-image datasets, but synthetic images are only useful when they improve downstream task performance. "Augmentation" here means synthetic supplementation: GAN-generated…

Image and Video Processing · Electrical Eng. & Systems 2026-05-25 José Rafael Noriega Cedeño

Purpose: Dual-energy CT (DECT) has been shown to derive stopping power ratio (SPR) map with higher accuracy than conventional single energy CT (SECT) by obtaining the energy dependence of photon interactions. However, DECT is not as widely…

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 John R. McNulty , Lee Kho , Alexandria L. Case , Charlie Fornaca , Drew Johnston , David Slater , Joshua M. Abzug , Sybil A. Russell

Computed Tomography (CT) is an imaging technique where information about an object are collected at different angles (called projections or scans). Then the cross-sectional image showing the internal structure of the slice is produced by…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Zhengchun Liu , Rajkumar Kettimuthu , Ian Foster

Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Zizhao Zhang , Lin Yang , Yefeng Zheng

Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Mohamed S. Elmahdy , Laurens Beljaards , Sahar Yousefi , Hessam Sokooti , Fons Verbeek , U. A. van der Heide , Marius Staring

This paper proposes a novel, unsupervised super-resolution (SR) approach for performing the SR of a clinical CT into the resolution level of a micro CT ($\mu$CT). The precise non-invasive diagnosis of lung cancer typically utilizes clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Tong Zheng , Hirohisa Oda , Masahiro Oda , Shota Nakamura , Masaki Mori , Hirotsugu Takabatake , Hiroshi Natori , Kensaku Mori

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

Medical Physics · Physics 2019-03-20 Monika Varga-Kofarago

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

Background: Cone-beam computed tomography (CBCT) plays a crucial role in image-guided radiotherapy, but artifacts and noise make them unsuitable for accurate dose calculation. Artificial intelligence methods have shown promise in enhancing…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Shi Yin , Hongqi Tan , Li Ming Chong , Haofeng Liu , Hui Liu , Kang Hao Lee , Jeffrey Kit Loong Tuan , Dean Ho , Yueming Jin

Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu
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