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Purpose: This study assessed the dosimetric accuracy of synthetic CT images generated from magnetic resonance imaging (MRI) data for focal brain radiation therapy, using a deep learning approach. Material and Methods: We conducted a study…
Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…
Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…
Computed tomography (CT) is a widely used imaging modality for medical diagnosis and treatment. In electroencephalography (EEG), CT imaging is necessary for co-registering with magnetic resonance imaging (MRI) and for creating more accurate…
Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…
Deep learning techniques, particularly convolutional neural networks (CNNs), have gained traction for synthetic computed tomography (sCT) generation from Magnetic resonance imaging (MRI), Cone-beam computed tomography (CBCT) and PET. In…
In many clinical settings, the use of both Computed Tomography (CT) and Magnetic Resonance (MRI) is necessary to pursue a thorough understanding of the patient's anatomy and to plan a suitable therapeutical strategy; this is often the case…
Recently, deep learning (DL)-based methods for the generation of synthetic computed tomography (sCT) have received significant research attention as an alternative to classical ones. We present here a systematic review of these methods by…
Background: In MR-guided proton therapy planning, aligning MR and CT images is key for MR-based CT synthesis, especially in mobile regions like the head-and-neck. Misalignments here can lead to less accurate synthetic CT (sCT) images,…
MRI provides superior soft tissue contrast without ionizing radiation; however, the absence of electron density information limits its direct use for dose calculation. As a result, current radiotherapy workflows rely on combined MRI and CT…
Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…
A key step in Adaptive Radiation Therapy (ART) workflows is the evaluation of the patient's anatomy at treatment time to ensure the accuracy of the delivery. To this end, Cone Beam Computerized Tomography (CBCT) is widely used being…
Supervised synthetic CT generation from CBCT requires registered training pairs, yet perfect registration between separately acquired scans remains unattainable. This registration bias propagates into trained models and corrupts standard…
Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…
Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for…
Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…
Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…
MR-only radiotherapy treatment planning requires accurate MR-to-CT synthesis. Current deep learning methods for MR-to-CT synthesis depend on pairwise aligned MR and CT training images of the same patient. However, misalignment between…
Accurate MR-to-CT synthesis is a requirement for MR-only workflows in radiotherapy (RT) treatment planning. In recent years, deep learning-based approaches have shown impressive results in this field. However, to prevent downstream errors…