Related papers: Characterisation of Anti-Arrhythmic Drug Effects o…
Electroanatomical maps are a key tool in the diagnosis and treatment of atrial fibrillation. Current approaches focus on the activation times recorded. However, more information can be extracted from the available data. The fibers in…
The contractile motion of the heart is strongly determined by the distribution of the fibers that constitute cardiac tissue. Strain analysis informed with the orientation of fibers allows to describe several pathologies that are typically…
Accurate modeling of drug release is essential for designing and developing controlled-release systems. Classical models (Fick, Higuchi, Peppas) rely on simplifying assumptions that limit their accuracy in complex geometries and release…
Electroencephalography (EEG) is extensively employed in medical diagnostics and brain-computer interface (BCI) applications due to its non-invasive nature and high temporal resolution. However, EEG analysis faces significant challenges,…
Scientific machine learning (SciML) represents a significant advancement in integrating machine learning (ML) with scientific methodologies. At the forefront of this development are Physics-Informed Neural Networks (PINNs), which offer a…
The link between in vitro hERG ion channel inhibition and subsequent in vivo QT interval prolongation, a critical risk factor for the development of arrythmias such as Torsade de Pointes, is so well established that in vitro hERG activity…
Accurately simulating systems governed by PDEs, such as voltage fields in cardiac electrophysiology (EP) modelling, remains a significant modelling challenge. Traditional numerical solvers are computationally expensive and sensitive to…
Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…
We propose FiberNet, a method to estimate \emph{in-vivo} the cardiac fiber architecture of the human atria from multiple catheter recordings of the electrical activation. Cardiac fibers play a central role in the electro-mechanical function…
The effectiveness of the Physics Informed Neural Networks (PINNs) for learning the dynamics of constrained Hamiltonian systems is demonstrated using the Dirac theory of constraints for regular systems with holonomic constraints and systems…
Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…
We introduce a physics-informed neural network (PINNs) framework for modelling the spatial distribution of chromodynamic fields induced by quark-antiquark pairs, based on lattice Monte Carlo simulations. In contrast to conventional neural…
Electrical submersible pumps (ESPs) are prevalently utilized as artificial lift systems in the oil and gas industry. These pumps frequently encounter multiphase flows comprising a complex mixture of hydrocarbons, water, and sediments. Such…
Accurate myocardial image registration is essential for cardiac strain analysis and disease diagnosis. However, spectral bias in neural networks impedes modeling high-frequency deformations, producing inaccurate, biomechanically implausible…
The anisotropic structure of the myocardium is a key determinant of the cardiac function. To date, there is no imaging modality to assess in-vivo the cardiac fiber structure. We recently proposed Fibernet, a method for the automatic…
This study benchmarks hybrid quantum physics-informed neural network (HQPINN) to model high-speed flows, compared against classical physics-informed neural networks (PINNs) and fully quantum neural networks (QNNs). The HQPINN architecture…
Due to the limited accuracy of 4D Magnetic Resonance Imaging (MRI) in identifying hemodynamics in cardiovascular diseases, the challenges in obtaining patient-specific flow boundary conditions, and the computationally demanding and…
We propose characteristics-informed neural networks (CINN), a simple and efficient machine learning approach for solving forward and inverse problems involving hyperbolic PDEs. Like physics-informed neural networks (PINN), CINN is a…
Although combination antiretroviral therapy (ART) is highly effective in suppressing viral load for people with HIV (PWH), many ART agents may exacerbate central nervous system (CNS)-related adverse effects including depression. Therefore,…
Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…