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Developing dialogue relation extraction (DRE) systems often requires a large amount of labeled data, which can be costly and time-consuming to annotate. In order to improve scalability and support diverse, unseen relation extraction, this…

Computation and Language · Computer Science 2023-06-13 Ze-Song Xu , Yun-Nung Chen

Electronic health records (EHRs) contain valuable patient data for health-related prediction tasks, such as disease prediction. Traditional approaches rely on supervised learning methods that require large labeled datasets, which can be…

Computation and Language · Computer Science 2024-03-26 Hejie Cui , Zhuocheng Shen , Jieyu Zhang , Hui Shao , Lianhui Qin , Joyce C. Ho , Carl Yang

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

Predicting drug-target interaction is key for drug discovery. Recent deep learning-based methods show promising performance but two challenges remain: (i) how to explicitly model and learn local interactions between drugs and targets for…

Machine Learning · Computer Science 2023-01-23 Peizhen Bai , Filip Miljković , Bino John , Haiping Lu

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

Computation and Language · Computer Science 2023-11-21 Ilseyar Alimova , Elena Tutubalina

Zero-Shot Stance Detection (ZSSD) identifies the attitude of the post toward unseen targets. Existing research using contrastive, meta-learning, or data augmentation suffers from generalizability issues or lack of coherence between text and…

Computation and Language · Computer Science 2025-11-06 Apoorva Upadhyaya , Wolfgang Nejdl , Marco Fisichella

In recent years, the field of precision medicine has seen many advancements. Significant focus has been placed on creating algorithms to estimate individualized treatment rules (ITR), which map from patient covariates to the space of…

Methodology · Statistics 2021-12-09 Kushal S. Shah , Haoda Fu , Michael R. Kosorok

Zero-shot classification enables text to be classified into classes not seen during training. In this study, we examine the efficacy of zero-shot learning models in classifying healthcare consultation responses from Doctors and AI systems.…

Computation and Language · Computer Science 2024-01-15 Olumide E. Ojo , Olaronke O. Adebanji , Alexander Gelbukh , Hiram Calvo , Anna Feldman

Due to the subtleness, implicity, and different possible interpretations perceived by different people, detecting undesirable content from text is a nuanced difficulty. It is a long-known risk that language models (LMs), once trained on…

Computation and Language · Computer Science 2022-05-26 Yau-Shian Wang , Yingshan Chang

Accurately predicting drug-drug interactions (DDIs) is crucial for pharmaceutical research and clinical safety. Recent deep learning models often suffer from high computational costs and limited generalization across datasets. In this…

Biomolecules · Quantitative Biology 2025-04-01 Manel Gil-Sorribes , Alexis Molina

Predicting drug-target interactions (DTI) is an essential part of the drug discovery process, which is an expensive process in terms of time and cost. Therefore, reducing DTI cost could lead to reduced healthcare costs for a patient. In…

Machine Learning · Computer Science 2019-08-20 Bonggun Shin , Sungsoo Park , Keunsoo Kang , Joyce C. Ho

This paper introduces Unified Language-driven Zero-shot Domain Adaptation (ULDA), a novel task setting that enables a single model to adapt to diverse target domains without explicit domain-ID knowledge. We identify the constraints in the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Senqiao Yang , Zhuotao Tian , Li Jiang , Jiaya Jia

Zero-shot Learners are models capable of predicting unseen classes. In this work, we propose a Zero-shot Learning approach for text categorization. Our method involves training model on a large corpus of sentences to learn the relationship…

Computation and Language · Computer Science 2017-12-27 Pushpankar Kumar Pushp , Muktabh Mayank Srivastava

Large Language Models (LLMs) have made great strides in areas such as language processing and computer vision. Despite the emergence of diverse techniques to improve few-shot learning capacity, current LLMs fall short in handling the…

Biomolecules · Quantitative Biology 2024-05-14 Xianggen Liu , Yan Guo , Haoran Li , Jin Liu , Shudong Huang , Bowen Ke , Jiancheng Lv

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

Machine Learning · Computer Science 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

Drug repositioning offers an effective solution to drug discovery, saving both time and resources by finding new indications for existing drugs. Typically, a drug takes effect via its protein targets in the cell. As a result, it is…

Quantitative Methods · Quantitative Biology 2018-11-26 Maryam Lotfi Shahreza , Nasser Ghadiri , Seyed Rasul Mossavi , Jaleh Varshosaz , James Green

Deep learning-based drug response prediction (DRP) methods can accelerate the drug discovery process and reduce R\&D costs. Although the mainstream methods achieve high accuracy in predicting response regression values, the regression-aware…

Biomolecules · Quantitative Biology 2023-12-19 Kun Li , Wenbin Hu

Dialogue systems for Automatic Differential Diagnosis (ADD) have a wide range of real-life applications. These dialogue systems are promising for providing easy access and reducing medical costs. Building end-to-end ADD dialogue systems…

Computation and Language · Computer Science 2023-08-17 Srija Macherla , Man Luo , Mihir Parmar , Chitta Baral

Large pre-trained language models (LLMs) have been shown to have significant potential in few-shot learning across various fields, even with minimal training data. However, their ability to generalize to unseen tasks in more complex fields,…

Computation and Language · Computer Science 2023-04-24 Tianhao Li , Sandesh Shetty , Advaith Kamath , Ajay Jaiswal , Xianqian Jiang , Ying Ding , Yejin Kim

We propose a reinforcement learning (RL)-based system that would automatically prescribe a hypothetical patient medication that may help the patient with their mental health-related speech disfluency, and adjust the medication and the…

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