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Multiple instance learning (MIL)-based framework has become the mainstream for processing the whole slide image (WSI) with giga-pixel size and hierarchical image context in digital pathology. However, these methods heavily depend on a…

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Vision Language Models (VLMs) like CLIP have attracted substantial attention in pathology, serving as backbones for applications such as zero-shot image classification and Whole Slide Image (WSI) analysis. Additionally, they can function as…

Oral mucosal diseases such as leukoplakia, oral lichen planus, and recurrent aphthous ulcers exhibit diverse and overlapping visual features, making diagnosis challenging for non-specialists. While vision-language models (VLMs) have shown…

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Vision-Language models (VLMs) that use contrastive language-image pre-training have shown promising zero-shot classification performance. However, their performance on imbalanced dataset is relatively poor, where the distribution of classes…

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Mammography is the primary imaging tool for breast cancer diagnosis. Despite significant strides in applying deep learning to interpret mammography images, efforts that focus predominantly on visual features often struggle with…

Vision-language pre-training (VLP) has recently proven highly effective for various uni- and multi-modal downstream applications. However, most existing end-to-end VLP methods use high-resolution image-text box data to perform well on…

With the availability of large-scale, comprehensive, and general-purpose vision-language (VL) datasets such as MSCOCO, vision-language pre-training (VLP) has become an active area of research and proven to be effective for various VL tasks…

While MLLMs perform well on perceptual tasks, they lack precise multimodal alignment, limiting performance. To address this challenge, we propose Vision Dynamic Embedding-Guided Pretraining (VDEP), a hybrid autoregressive training paradigm…

Large Language Model-based Vision-Language Models (LLM-based VLMs) have demonstrated impressive results in various vision-language understanding tasks. However, how well these VLMs can see image detail beyond the semantic level remains…

3D vision-language (VL) reasoning has gained significant attention due to its potential to bridge the 3D physical world with natural language descriptions. Existing approaches typically follow task-specific, highly specialized paradigms.…

Vision-language foundation models have shown great promise in computational pathology but remain primarily data-driven, lacking explicit integration of medical knowledge. We introduce KEEP (KnowledgE-Enhanced Pathology), a foundation model…

Deep learning for medical imaging is hampered by task-specific models that lack generalizability and prognostic capabilities, while existing 'universal' approaches suffer from simplistic conditioning and poor medical semantic understanding.…

Despite significant advancements, large multimodal models (LMMs) still struggle to bridge the gap between low-level visual perception -- focusing on shapes, sizes, and layouts -- and high-level language reasoning, such as semantics and…

A large-scale image-text pair dataset has greatly contributed to the development of vision-language pre-training (VLP) models, which enable zero-shot or few-shot classification without costly annotation. However, in the medical domain, the…

Lesion detection, symptom tracking, and visual explainability are central to real-world medical image analysis, yet current medical Vision-Language Models (VLMs) still lack mechanisms that translate their broad knowledge into clinically…

Vision-Language Pretraining (VLP) has shown impressive results on diverse downstream tasks by offline training on large-scale datasets. Regarding the growing nature of real-world data, such an offline training paradigm on ever-expanding…

In this work, we address the problem of grounding abnormalities in medical images, where the goal is to localize clinical findings based on textual descriptions. While generalist Vision-Language Models (VLMs) excel in natural grounding…