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Related papers: CardioGenAI: A Machine Learning-Based Framework fo…

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The management of chronic Heart Failure (HF) presents significant challenges in modern healthcare, requiring continuous monitoring, early detection of exacerbations, and personalized treatment strategies. In this paper, we present a…

Identifying associations between imaging phenotypes, disease risk factors, and clinical outcomes is essential for understanding disease mechanisms. However, traditional approaches rely on human-driven hypothesis testing and selection of…

Artificial Intelligence · Computer Science 2025-09-09 Weitong Zhang , Mengyun Qiao , Chengqi Zang , Steven Niederer , Paul M Matthews , Wenjia Bai , Bernhard Kainz

Machine learning (ML) methods have the potential to automate clinical EEG analysis. They can be categorized into feature-based (with handcrafted features), and end-to-end approaches (with learned features). Previous studies on EEG pathology…

Methods: We developed a self-supervised deep learning model that extracts meaningful patterns from multi-modal signals (Electroencephalography (EEG), Electrocardiography (ECG), and respiratory signals). The model was trained on data from…

Machine Learning · Computer Science 2025-07-15 Zhengxiao He , Huayu Li , Geng Yuan , William D. S. Killgore , Stuart F. Quan , Chen X. Chen , Ao Li

Objective. Arrhythmia classification from electrocardiograms (ECGs) suffers from high false positive rates and limited cross-dataset generalization, particularly for atrial fibrillation (AF) detection where specificity ranges from 0.72 to…

Machine Learning · Computer Science 2026-02-16 Tiezhi Wang , Wilhelm Haverkamp , Nils Strodthoff

Classification of motor imagery (MI) using non-invasive electroencephalographic (EEG) signals is a critical objective as it is used to predict the intention of limb movements of a subject. In recent research, convolutional neural network…

Machine Learning · Computer Science 2025-07-03 Taveena Lotey , Prateek Keserwani , Debi Prosad Dogra , Partha Pratim Roy

Chronic neck pain is a leading cause of disability worldwide, and current treatment selection remains largely trial and error. We present a machine learning framework that uses electroencephalography to predict treatment efficacy in…

Quantitative Methods · Quantitative Biology 2026-05-19 Xiru Wang , Aiden Li , Hongzhao Tan , Stevie Foglia , Aimee Nelson , Zhen Gao

Neuroevolution is a powerful method of applying an evolutionary algorithm to refine the performance of artificial neural networks through natural selection; however, the fitness evaluation of these networks can be time-consuming and…

Neural and Evolutionary Computing · Computer Science 2024-04-18 Derek Whitley

Background: Artificial intelligence enabled electrocardiography (AI-ECG) has demonstrated the ability to detect diverse pathologies, but most existing models focus on single disease identification, neglecting comorbidities and future risk…

Signal Processing · Electrical Eng. & Systems 2026-01-19 Jun Li , Hongling Zhu , Yujie Xiao , Qinghao Zhao , Yalei Ke , Gongzheng Tang , Guangkun Nie , Deyun Zhang , Jin Li , Canqing Yu , Shenda Hong

While drug discovery is vital for human health, the process remains inefficient. Medicinal chemists must navigate a vast protein space to identify target proteins that meet three criteria: physical and functional interactions, therapeutic…

With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge.…

Computation and Language · Computer Science 2025-10-14 Yi Wang , Haoran Luo , Lu Meng , Ziyu Jia , Xinliang Zhou , Qingsong Wen

Predicting long-term loan defaults is hard because borrower behavior often changes and data distributions shift over time. This paper presents HYDRA-EI, a hybrid ensemble incremental learning framework. It uses several stages of feature…

Machine Learning · Computer Science 2025-10-10 Jiajing Wang

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

Medical Physics · Physics 2026-03-05 Nathan Dermul , Hans Dierckx

Drug repurposing (or repositioning) is the process of finding new therapeutic uses for drugs already approved by drug regulatory authorities (e.g., the Food and Drug Administration (FDA) and Therapeutic Goods Administration (TGA)) for other…

Artificial Intelligence · Computer Science 2023-06-27 Chaarvi Bansal , Rohitash Chandra , Vinti Agarwal , P. R. Deepa

The rational design of novel molecules with desired bioactivity is a critical but challenging task in drug discovery, especially when treating a novel target family or understudied targets. Here, we propose PGMG, a pharmacophore-guided deep…

Biomolecules · Quantitative Biology 2022-07-05 Huimin Zhu , Renyi Zhou , Jing Tang , Min Li

Hierarchical text classification (HTC) is a complex subtask under multi-label text classification, characterized by a hierarchical label taxonomy and data imbalance. The best-performing models aim to learn a static representation by…

Computation and Language · Computer Science 2024-02-23 Vidit Jain , Mukund Rungta , Yuchen Zhuang , Yue Yu , Zeyu Wang , Mu Gao , Jeffrey Skolnick , Chao Zhang

Electrocardiogram data, one of the most widely available biosignal data, has become increasingly valuable with the emergence of deep learning methods, providing novel insights into cardiovascular diseases and broader health conditions.…

Machine Learning · Computer Science 2026-02-03 Lucas Bickmann , Lucas Plagwitz , Antonius Büscher , Lars Eckardt , Julian Varghese

Predicting the bioactivity of a ligand is one of the hardest and most important challenges in computer-aided drug discovery. Despite years of data collection and curation efforts by research organizations worldwide, bioactivity data remains…

Quantitative Methods · Quantitative Biology 2023-08-21 Lucian Chan , Marcel Verdonk , Carl Poelking

Recent advancements in the field of Artificial Intelligence (AI) establish the basis to address challenging tasks. However, with the integration of AI, new risks arise. Therefore, to benefit from its advantages, it is essential to…

Machine Learning · Computer Science 2024-12-20 Ronald Schnitzer , Andreas Hapfelmeier , Sven Gaube , Sonja Zillner

In an ideal medical environment, real-time coagulation monitoring can enable early detection and prompt remediation of risks. However, traditional Thromboelastography (TEG), a widely employed diagnostic modality, can only provide such…

Machine Learning · Computer Science 2026-01-13 Yulu Wang , Ziqian Zeng , Jianjun Wu , Zhifeng Tang