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The paradigm of electrocardiogram (ECG) analysis has evolved into real-time digital analysis, facilitated by artificial intelligence (AI) and machine learning (ML), which has improved the diagnostic precision and predictive capacity of…

Introduction: Heart failure with preserved ejection fraction (HFpEF) arises from diverse comorbidities and progresses through prolonged subclinical stages, making early diagnosis and prognosis difficult. Current echocardiography-based…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Andrés Bell-Navas , Jesús Garicano-Mena , Antonella Ausiello , Soledad Le Clainche , María Villalba-Orero , Enrique Lara-Pezzi

Cardiac arrhythmias are a leading cause of life-threatening cardiac events, highlighting the urgent need for accurate and timely detection. Electrocardiography (ECG) remains the clinical gold standard for arrhythmia diagnosis; however,…

Machine Learning · Computer Science 2025-05-09 Zuraiz Baig , Sidra Nasir , Rizwan Ahmed Khan , Muhammad Zeeshan Ul Haque

Cardiac rehabilitation constitutes a structured clinical process involving multiple interdependent phases, individualized medical decisions, and the coordinated participation of diverse healthcare professionals. This sequential and adaptive…

Machine Learning · Computer Science 2025-12-25 Alexandre Cabodevila , Pedro Gamallo-Fernandez , Juan C. Vidal , Manuel Lama

Combination therapy has shown to improve therapeutic efficacy while reducing side effects. Importantly, it has become an indispensable strategy to overcome resistance in antibiotics, anti-microbials, and anti-cancer drugs. Facing enormous…

Molecular Networks · Quantitative Biology 2020-04-24 Mostafa Karimi , Arman Hasanzadeh , Yang shen

Cardiac arrest remains a leading cause of death worldwide, necessitating proactive measures for early detection and intervention. This project aims to develop and assess predictive models for the timely identification of cardiac arrest…

Computers and Society · Computer Science 2024-09-25 G. Divya , M. Naga SravanKumar , T. JayaDharani , B. Pavan , K. Praveen

Atrial fibrillation (AF) is one of the most prevalent cardiac arrhythmias that affects the lives of more than 3 million people in the U.S. and over 33 million people around the world and is associated with a five-fold increased risk of…

Quantitative Methods · Quantitative Biology 2020-02-14 Sajad Mousavi , Fatemeh Afghah , U. Rajendra Acharya

Malignant ventricular arrhythmias (VT/VF) following acute myocardial infarction (AMI) are a major cause of in-hospital death, yet early identification remains a clinical challenge. While traditional risk scores have limited performance,…

Artificial Intelligence · Computer Science 2025-10-21 Shun Huang , Wenlu Xing , Shijia Geng , Hailong Wang , Guangkun Nie , Gongzheng Tang , Chenyang He , Shenda Hong

Heart failure (HF) affects 11.8% of adults aged 65 and older, reducing quality of life and longevity. Preventing HF can reduce morbidity and mortality. We hypothesized that artificial intelligence (AI) applied to 24-hour single-lead…

Signal Processing · Electrical Eng. & Systems 2026-01-05 Eran Zvuloni , Ronit Almog , Michael Glikson , Shany Brimer Biton , Ilan Green , Izhar Laufer , Offer Amir , Joachim A. Behar

Accurate cardiac motion estimation from cine cardiac magnetic resonance (CMR) images is vital for assessing cardiac function and detecting its abnormalities. Existing methods often struggle to capture heart motion accurately because they…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Reza Akbari Movahed , Abuzar Rezaee , Arezoo Zakeri , Colin Berry , Edmond S. L. Ho , Ali Gooya

Drug-target interaction (DTI) prediction has become a foundational task in drug repositioning, polypharmacology, drug discovery, as well as drug resistance and side-effect prediction. DTI identification using machine learning is gaining…

Quantitative Methods · Quantitative Biology 2023-11-17 Konstantin Y. Kalitin , Alexey A. Nevzorov , Denis A. Babkov , Alexander A. Spasov , Olga Y. Mukha

Artificial intelligence has made great progress in medical data analysis, but the lack of robustness and trustworthiness has kept these methods from being widely deployed. As it is not possible to train networks that are accurate in all…

Machine Learning · Computer Science 2024-02-19 Christopher Wiedeman , Ge Wang

Medication recommendation systems play a crucial role in assisting clinicians with personalized treatment decisions. While existing approaches have made significant progress in learning medication representations, they suffer from two…

Machine Learning · Computer Science 2025-11-19 Kelin Ren , Chan-Yang Ju , Dong-Ho Lee

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Anemia is a prevalent medical condition that typically requires invasive blood tests for diagnosis and monitoring. Electronic health records (EHRs) have emerged as valuable data sources for numerous medical studies. EHR-based hemoglobin…

Machine Learning · Computer Science 2024-01-23 Zhuo Zhi , Moe Elbadawi , Adam Daneshmend , Mine Orlu , Abdul Basit , Andreas Demosthenous , Miguel Rodrigues

The alarmingly high mortality rate and increasing global prevalence of cardiovascular diseases signify the crucial need for early detection schemes. Phonocardiogram (PCG) signals have been historically applied in this domain owing to its…

Audio and Speech Processing · Electrical Eng. & Systems 2021-03-09 Samiul Based Shuvo , Shams Nafisa Ali , Soham Irtiza Swapnil , Mabrook S. Al-Rakhami , Abdu Gumaei

The widespread application of Artificial Intelligence (AI) techniques has significantly influenced the development of new therapeutic agents. These computational methods can be used to design and predict the properties of generated…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Arthur Cerveira , Frederico Kremer , Darling de Andrade Lourenço , Ulisses B Corrêa

Cardiac disease is the leading cause of death in the US. Accurate heart disease detection is of critical importance for timely medical treatment to save patients' lives. Routine use of electrocardiogram (ECG) is the most common method for…

Signal Processing · Electrical Eng. & Systems 2022-10-21 Zekai Wang , Stavros Stavrakis , Bing Yao

Forecasting complex system dynamics, particularly for long-term predictions, is persistently hindered by error accumulation and computational burdens. This study presents RefreshNet, a multiscale framework developed to overcome these…

Machine Learning · Computer Science 2024-01-25 Junaid Farooq , Danish Rafiq , Pantelis R. Vlachas , Mohammad Abid Bazaz

Objective: We develop a channel-adaptive (CA) architecture that seamlessly processes multi-variate time-series with an arbitrary number of channels, and in particular intracranial electroencephalography (iEEG) recordings. Methods: Our CA…

Machine Learning · Computer Science 2025-12-23 Francesco Carzaniga , Michael Hersche , Kaspar Schindler , Abbas Rahimi