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Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

This paper describes an effective and efficient image classification framework nominated distributed deep representation learning model (DDRL). The aim is to strike the balance between the computational intensive deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2016-07-05 Le Dong , Na Lv , Qianni Zhang , Shanshan Xie , Ling He , Mengdie Mao

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Melanoma is a serious form of skin cancer with high mortality rate at later stages. Fortunately, when detected early, the prognosis of melanoma is promising and malignant melanoma incidence rates are relatively low. As a result, datasets…

Computer Vision and Pattern Recognition · Computer Science 2022-08-11 M. M. Amaan Valiuddin , Christiaan G. A. Viviers , Ruud J. G. van Sloun , Peter H. N. de With , Fons van der Sommen

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Ju Xu , Mengzhang Li , Zhanxing Zhu

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Background: Skin cancer is one of the widely seen cancer worldwide and automatic classification of skin cancer can be benefited dermatology clinics for an accurate diagnosis. Hence, a machine learning-based automatic skin cancer detection…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Mehmet Baygin , Turker Tuncer , Sengul Dogan

In recent years, semi-supervised graph learning with data augmentation (DA) is currently the most commonly used and best-performing method to enhance model robustness in sparse scenarios with few labeled samples. Differing from homogeneous…

Machine Learning · Computer Science 2022-12-02 Ying Chen , Siwei Qiang , Mingming Ha , Xiaolei Liu , Shaoshuai Li , Lingfeng Yuan , Xiaobo Guo , Zhenfeng Zhu

Reliable large-scale cell detection and segmentation is the fundamental first step to understanding biological processes in the brain. The ability to phenotype cells at scale can accelerate preclinical drug evaluation and system-level brain…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Son T. Ly , Bai Lin , Hung Q. Vo , Dragan Maric , Badri Roysam , Hien V. Nguyen

Accurate image segmentation remains challenging, particularly in generating sharp, confident boundaries. While modern architectures have advanced the field, many of them still rely on standard loss functions like Cross-Entropy and Dice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Adam Dawid Sztamborski , Raül Pérez-Gonzalo , Antonio Agudo

Medical image analysis plays a pivotal role in the early diagnosis of diseases such as skin lesions. However, the scarcity of data and the class imbalance significantly hinder the performance of deep learning models. We propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Zhaobin Xu

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Bastiaan S. Veeling , Jasper Linmans , Jim Winkens , Taco Cohen , Max Welling

The heterogeneity of breast cancer presents considerable challenges for its early detection, prognosis, and treatment selection. Convolutional neural networks often neglect the spatial relationships within histopathological images, which…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Akhila Krishna K , Ravi Kant Gupta , Nikhil Cherian Kurian , Pranav Jeevan , Amit Sethi

Tumor segmentation in histopathology images is often complicated by its composition of different histological subtypes and class imbalance. Oversampling subtypes with low prevalence features is not a satisfactory solution since it…

One of the fundamental problems in machine learning is the estimation of a probability distribution from data. Many techniques have been proposed to study the structure of data, most often building around the assumption that observations…

Machine Learning · Statistics 2013-02-22 Oren Rippel , Ryan Prescott Adams

Linear Discriminant Analysis (LDA) is a well-known technique for feature extraction and dimension reduction. The performance of classical LDA, however, significantly degrades on the High Dimension Low Sample Size (HDLSS) data for the…

Machine Learning · Computer Science 2023-03-09 Sijia Yang , Haoyi Xiong , Kaibo Xu , Licheng Wang , Jiang Bian , Zeyi Sun