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Interpretability is highly desired for deep neural network-based classifiers, especially when addressing high-stake decisions in medical imaging. Commonly used post-hoc interpretability methods have the limitation that they can produce…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Sourya Sengupta , Mark A. Anastasio

Despite recent advances in machine learning and explainable AI, a gap remains in personalized preventive healthcare: predictions, interventions, and recommendations should be both understandable and verifiable for all stakeholders in the…

Deep learning models have achieved remarkable accuracy in chest X-ray diagnosis, yet their widespread clinical adoption remains limited by the black-box nature of their predictions. Clinicians require transparent, verifiable explanations to…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yiming Tang , Wenjia Zhong , Rushi Shah , Dianbo Liu

Transformer models typically calculate attention matrices using dot products, which have limitations when capturing nonlinear relationships between embedding vectors. We propose Neural Attention, a technique that replaces dot products with…

Machine Learning · Computer Science 2025-11-10 Andrew DiGiugno , Ausif Mahmood

The imperative to comprehend the behaviors of deep learning models is of utmost importance. In this realm, Explainable Artificial Intelligence (XAI) has emerged as a promising avenue, garnering increasing interest in recent years. Despite…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Bowen Wang , Liangzhi Li , Jiahao Zhang , Yuta Nakashima , Hajime Nagahara

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

The remarkable performance of the Transformer architecture in natural language processing has recently also triggered broad interest in Computer Vision. Among other merits, Transformers are witnessed as capable of learning long-range…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Reza Azad , Amirhossein Kazerouni , Moein Heidari , Ehsan Khodapanah Aghdam , Amirali Molaei , Yiwei Jia , Abin Jose , Rijo Roy , Dorit Merhof

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

In this work, we present RadioTransformer, a novel visual attention-driven transformer framework, that leverages radiologists' gaze patterns and models their visuo-cognitive behavior for disease diagnosis on chest radiographs. Domain…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Moinak Bhattacharya , Shubham Jain , Prateek Prasanna

In the field of chest X-ray (CXR) diagnosis, existing works often focus solely on determining where a radiologist looks, typically through tasks such as detection, segmentation, or classification. However, these approaches are often…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Trong Thang Pham , Jacob Brecheisen , Anh Nguyen , Hien Nguyen , Ngan Le

Medical imaging is a key component in clinical diagnosis, treatment planning and clinical trial design, accounting for almost 90% of all healthcare data. CNNs achieved performance gains in medical image analysis (MIA) over the last years.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Giorgos Papanastasiou , Nikolaos Dikaios , Jiahao Huang , Chengjia Wang , Guang Yang

Explainable artificial intelligence has been gaining attention in the past few years. However, most existing methods are based on gradients or intermediate features, which are not directly involved in the decision-making process of the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Liangzhi Li , Bowen Wang , Manisha Verma , Yuta Nakashima , Ryo Kawasaki , Hajime Nagahara

Transformers are built upon multi-head scaled dot-product attention and positional encoding, which aim to learn the feature representations and token dependencies. In this work, we focus on enhancing the distinctive representation by…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Litao Yu , Jian Zhang

Although attention mechanisms have achieved considerable progress in Transformer-based architectures across various Artificial Intelligence (AI) domains, their inner workings remain to be explored. Existing explainable methods have…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Hongbo Zhu , Theodor Wulff , Rahul Singh Maharjan , Jinpei Han , Angelo Cangelosi

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Decision-making processes in healthcare can be highly complex and challenging. Machine Learning tools offer significant potential to assist in these processes. However, many current methodologies rely on complex models that are not easily…

Artificial Intelligence · Computer Science 2025-03-24 Alessio Cascione , Mattia Setzu , Federico A. Galatolo , Mario G. C. A. Cimino , Riccardo Guidotti

There have been several post-hoc explanation approaches developed to explain pre-trained black-box neural networks. However, there is still a gap in research efforts toward designing neural networks that are inherently explainable. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Subash Khanal , Benjamin Brodie , Xin Xing , Ai-Ling Lin , Nathan Jacobs

In Vitro Fertilization is among the most widespread treatments for infertility. One of its main challenges is the evaluation and selection of embryo for implantation, a process with large inter- and intra-clinician variability. Deep…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Lucia Urcelay , Daniel Hinjos , Pablo A. Martin-Torres , Marta Gonzalez , Marta Mendez , Salva Cívico , Sergio Álvarez-Napagao , Dario Garcia-Gasulla

We present a novel usage of Transformers to make image classification interpretable. Unlike mainstream classifiers that wait until the last fully connected layer to incorporate class information to make predictions, we investigate a…

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin