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Various approaches utilizing Transformer architectures have achieved state-of-the-art results in Natural Language Processing (NLP). Based on this success, numerous architectures have been proposed for other types of data, such as in…

Machine Learning · Computer Science 2025-01-15 Gabriel Bianchin de Oliveira , Helio Pedrini , Zanoni Dias

Hybrid quantum-classical models represent a crucial step toward leveraging near-term quantum devices for sequential data processing. We present Quantum Recurrent Neural Networks (QRNNs) and Quantum Convolutional Neural Networks (QCNNs) as…

Quantum Physics · Physics 2025-12-16 Stefan Balauca , Ada-Astrid Balauca , Adrian Iftene

Representation learning and \emph{de novo} generation of proteins are pivotal computational biology tasks. Whilst natural language processing (NLP) techniques have proven highly effective for protein sequence modelling, structure modelling…

Quantitative Methods · Quantitative Biology 2025-01-08 Benoit Gaujac , Jérémie Donà , Liviu Copoiu , Timothy Atkinson , Thomas Pierrot , Thomas D. Barrett

Running quantum algorithms often involves implementing complex quantum circuits with such a large number of multi-qubit gates that the challenge of tackling practical applications appears daunting. To date, no experiments have successfully…

Partial Differential Equations (PDEs) are used to model a variety of dynamical systems in science and engineering. Recent advances in deep learning have enabled us to solve them in a higher dimension by addressing the curse of…

Quantum Neural Networks (QNNs) are a promising variational learning paradigm with applications to near-term quantum processors, however they still face some significant challenges. One such challenge is finding good parameter initialization…

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

Quantum Physics · Physics 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images,…

Since classical machine learning has become a powerful tool for developing data-driven algorithms, quantum machine learning is expected to similarly impact the development of quantum algorithms. The literature reflects a mutually beneficial…

Quantum Physics · Physics 2024-12-13 Leandro C. Souza , Bruno C. Guingo , Gilson Giraldi , Renato Portugal

Proteins perform essential biological functions, and accurate classification of their sequences is critical for understanding structure-function relationships, enzyme mechanisms, and molecular interactions. This study presents a deep…

Quantitative Methods · Quantitative Biology 2025-11-19 Pratik Chakraborty , Aryan Bhargava

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

Quantum machine learning researchers often rely on incorporating Tensor Networks (TN) into Deep Neural Networks (DNN) and variational optimization. However, the standard optimization techniques used for training the contracted trainable…

Quantum Physics · Physics 2023-10-04 Debanjan Konar , Dheeraj Peddireddy , Vaneet Aggarwal , Bijaya K. Panigrahi

We describe a quantum-assisted machine learning (QAML) method in which multivariate data is encoded into quantum states in a Hilbert space whose dimension is exponentially large in the length of the data vector. Learning in this space…

Quantum Physics · Physics 2021-10-13 Michael L. Wall , Giuseppe D'Aguanno

We compare the performance of randomized classical and quantum neural networks (NNs) as well as classical and quantum-classical hybrid convolutional neural networks (CNNs) for the task of supervised binary image classification. We keep the…

Quantum Physics · Physics 2025-11-24 Daniel Basilewitsch , João F. Bravo , Christian Tutschku , Frederick Struckmeier

This paper seeks to model human language by the mathematical framework of quantum physics. With the well-designed mathematical formulations in quantum physics, this framework unifies different linguistic units in a single complex-valued…

Computation and Language · Computer Science 2019-04-11 Qiuchi Li , Benyou Wang , Massimo Melucci

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in…

Quantitative Methods · Quantitative Biology 2024-07-09 Yiqing Shen , Zan Chen , Michail Mamalakis , Luhan He , Haiyang Xia , Tianbin Li , Yanzhou Su , Junjun He , Yu Guang Wang

Quantum convolutional neural networks (QCNNs) have been introduced as classifiers for gapped quantum phases of matter. Here, we propose a model-independent protocol for training QCNNs to discover order parameters that are unchanged under…

Quantum Physics · Physics 2023-06-05 Yu-Jie Liu , Adam Smith , Michael Knap , Frank Pollmann

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

Quantum neural networks (QNNs) and quantum kernels stand as prominent figures in the realm of quantum machine learning, poised to leverage the nascent capabilities of near-term quantum computers to surmount classical machine learning…

Quantum Physics · Physics 2023-12-14 Yiming Huang , Huiyuan Wang , Yuxuan Du , Xiao Yuan

As the rapidly evolving field of machine learning continues to produce incredibly useful tools and models, the potential for quantum computing to provide speed up for machine learning algorithms is becoming increasingly desirable. In…

Quantum Physics · Physics 2024-04-02 Anthony M. Smaldone , Gregory W. Kyro , Victor S. Batista