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The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Deep learning models can excel on medical tasks, yet often experience spurious correlations, known as shortcut learning, leading to poor generalization in new environments. Particularly in medical imaging, where multiple spurious…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Louisa Fay , Hajer Reguigui , Bin Yang , Sergios Gatidis , Thomas Küstner

The success of Convolutional Neural Networks (CNNs) in 3D medical image segmentation relies on massive fully annotated 3D volumes for training that are time-consuming and labor-intensive to acquire. In this paper, we propose to annotate a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Shuwei Zhai , Guotai Wang , Xiangde Luo , Qiang Yue , Kang Li , Shaoting Zhang

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Applying machine learning technologies, especially deep learning, into medical image segmentation is being widely studied because of its state-of-the-art performance and results. It can be a key step to provide a reliable basis for clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Ziyang Wang

Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alexandre Benatti , Luciano da F. Costa

Denoising Diffusion Probabilistic models have become increasingly popular due to their ability to offer probabilistic modeling and generate diverse outputs. This versatility inspired their adaptation for image segmentation, where multiple…

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos

Deep neural networks with multilevel connections process input data in complex ways to learn the information.A networks learning efficiency depends not only on the complex neural network architecture but also on the input training…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Rajarajeswari Muthusivarajan , Adrian Celaya , Joshua P. Yung , Satish Viswanath , Daniel S. Marcus , Caroline Chung , David Fuentes

Deep learning has been widely accepted as a promising solution for medical image segmentation, given a sufficiently large representative dataset of images with corresponding annotations. With ever increasing amounts of annotated medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Philipp Fuernstahl , Orcun Goksel

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

The biological brain has inspired multiple advances in machine learning. However, most state-of-the-art models in computer vision do not operate like the human brain, simply because they are not capable of changing or improving their…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 David Calhas , João Marques , Arlindo L. Oliveira

Existing learning-based solutions to medical image segmentation have two important shortcomings. First, for most new segmentation task, a new model has to be trained or fine-tuned. This requires extensive resources and machine learning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Marianne Rakic , Hallee E. Wong , Jose Javier Gonzalez Ortiz , Beth Cimini , John Guttag , Adrian V. Dalca

Recent work has shown that label-efficient few-shot learning through self-supervision can achieve promising medical image segmentation results. However, few-shot segmentation models typically rely on prototype representations of the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Stine Hansen , Srishti Gautam , Robert Jenssen , Michael Kampffmeyer

The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zihang Liu , Chunhui Zhao

Deep learning has successfully been leveraged for medical image segmentation. It employs convolutional neural networks (CNN) to learn distinctive image features from a defined pixel-wise objective function. However, this approach can lead…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Kibrom Berihu Girum , Gilles Créhange , Alain Lalande

Semantic segmentation of medical images with deep learning models is rapidly developed. In this study, we benchmarked state-of-the-art deep learning segmentation algorithms on our clinical stereotactic radiosurgery dataset, demonstrating…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Siang-Ruei Wu , Hao-Yun Chang , Florence T Su , Heng-Chun Liao , Wanju Tseng , Chun-Chih Liao , Feipei Lai , Feng-Ming Hsu , Furen Xiao

Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Deep convolutional neural networks (CNNs) have been widely used for medical image segmentation. In most studies, only the output layer is exploited to compute the final segmentation results and the hidden representations of the deep learned…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Sheng He , Yanfang Feng , P. Ellen Grant , Yangming Ou

As interest in applying machine learning techniques for medical images continues to grow at a rapid pace, models are starting to be developed and deployed for clinical applications. In the clinical AI model development lifecycle (described…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Giorgio Pietro Biondetti , Romane Gauriau , Christopher P. Bridge , Charles Lu , Katherine P. Andriole