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Liquid-liquid phase separation has recently emerged as an important topic in the context of cellular organization. Within this context, there are multiple poorly understood features; for instance hints of critical behavior in the plasma…

Statistical Mechanics · Physics 2024-06-25 Felix Herrmann , Burkhard Dünweg , Martin Girard

The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…

Soft Condensed Matter · Physics 2024-02-20 Roman Golkov , Yair Shokef

Chemically active mixtures exhibit complex patterns that emerge from the interplay of physical interactions and reactions among components. Individually, these two processes are well-understood: Physical interactions can give rise to phase…

Soft Condensed Matter · Physics 2026-04-30 Chengjie Luo , Yicheng Qiang , Guido L. A. Kusters , David Zwicker

We study the thermodynamics of binary mixtures with the volume fraction of the minority component less than the amount required to form a flat interface and show that the surface tension dominated equilibrium phase of the mixture forms a…

Soft Condensed Matter · Physics 2023-03-07 Subhadip Biswas , Biswaroop Mukherjee , Buddhapriya Chakrabarti

Understanding the (de)mixing behavior of multicomponent lipid bilayers is an important step towards unraveling the nature of spatial composition heterogeneities in cellular membranes and their role in biological function. We use…

Soft Condensed Matter · Physics 2018-05-17 Shushan He , Lutz Maibaum

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

Spontaneous phase separation, or demixing, is important in biological phenomena such as cell sorting. In particle-based models, an open question is whether differences in diffusivity can drive such demixing. While…

Soft Condensed Matter · Physics 2023-07-10 Erin McCarthy , Ojan Damavandi , Raj Kumar Manna , M. Lisa Manning

Non-dyadic higher-order interactions affect collective behavior in various networked dynamical systems. Here we discuss the properties of a novel Ising model with higher-order interactions and characterize its phase transitions between the…

Statistical Mechanics · Physics 2024-12-02 Thomas Robiglio , Leonardo Di Gaetano , Ada Altieri , Giovanni Petri , Federico Battiston

Phase separation of multicomponent liquid mixtures plays an integral part in many processes ranging from industry to cellular biology. In many cases the morphology of coexisting phases is crucially linked to the function of the separated…

Soft Condensed Matter · Physics 2020-11-25 Sheng Mao , Milena S. Chakraverti-Wuerthwein , Hunter Gaudio , Andrej Kosmrlj

The phase behavior of a cross-linked polymer blend made of two incompatible species, $A$ and $B$, of different chemical nature is analyzed. Besides a homogeneous phase, this system also exhibits two microphases and a phase of total…

Condensed Matter · Physics 2007-05-23 Edilson Vargas , Marcia C. Barbosa

Concentration gradients play a critical role in embryogenesis, bacterial locomotion, as well as the motility of active particles. Particles develop concentration profiles around them by dissolution, adsorption, or the reactivity of surface…

The liquid-to-ordered phase transition in a bilayer system of fermions is studied within the context of a recently proposed density-functional theory [Phys. Rev. A {\bf 92}, 023614 (2015)]. In each two-dimensional layer, the fermions…

Quantum Gases · Physics 2016-06-01 B. P. van Zyl , W. Ferguson

The influence of size differences, shape, mass and persistent motion on phase separation in binary mixtures has been intensively studied. Here we focus on the exclusive role of diffusivity differences in binary mixtures of equal-sized…

Soft Condensed Matter · Physics 2016-03-04 Simon N. Weber , Christoph A. Weber , Erwin Frey

The liquid-liquid phase separation of biomolecules is an important process for intracellular organization. Biomolecular sequence combinatorics leads to a large variety of proteins and nucleic acids which can interact to form a diversity of…

Soft Condensed Matter · Physics 2025-08-27 Aria S. Chaderjian , Sam Wilken , Omar A. Saleh

We investigate in this paper the ground state and the nature of the transition from an orientational ordered phase at low temperature to the disordered state at high temperature in a molecular crystal. Our model is a Potts model which takes…

Statistical Mechanics · Physics 2015-06-03 Danh-Tai Hoang , H. T. Diep

A critical task in systems biology is the identification of genes that interact to control cellular processes by transcriptional activation of a set of target genes. Many methods have been developed to use statistical correlations in…

Quantitative Methods · Quantitative Biology 2010-11-24 Adam A. Margolin , Kai Wang , Andrea Califano , Ilya Nemenman

We present analysis of a system of three two-level atoms interacting with each other through the dipole-dipole interaction. The interaction manifests between excited state of one of the atoms and the ground state of its nearest neighbour.…

Atomic Physics · Physics 2014-02-18 P Anantha Lakshmi , Ashoka Vudayagiri , Shaik Ahmed

We present a minimal model to study liquid phase separation in a fixed pH ensemble. The model describes a mixture composed of macromolecules that exist in three different charge states and have a tendency to phase separate. We introduce the…

Biological Physics · Physics 2020-10-30 Omar Adame-Arana , Christoph A. Weber , Vasily Zaburdaev , Jacques Prost , Frank Jülicher

Biomolecules composed of a limited set of chemical building blocks can co-localize into distinct, spatially segregated compartments known as biomolecular condensates. While many condensates are known to form spontaneously via phase…

Soft Condensed Matter · Physics 2024-08-15 Fan Chen , William M. Jacobs

Active matter is not only indispensable to our understanding of diverse biological processes, but also provides a fertile ground for discovering novel physics. Many emergent properties impossible for equilibrium systems have been…

Soft Condensed Matter · Physics 2022-05-27 Thibault Bertrand , Chiu Fan Lee
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