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Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Tumor synthesis enables the creation of artificial tumors in medical images, facilitating the training of AI models for tumor detection and segmentation. However, success in tumor synthesis hinges on creating visually realistic tumors that…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Qi Chen , Xiaoxi Chen , Haorui Song , Zhiwei Xiong , Alan Yuille , Chen Wei , Zongwei Zhou

We develop a novel strategy to generate synthetic tumors. Unlike existing works, the tumors generated by our strategy have two intriguing advantages: (1) realistic in shape and texture, which even medical professionals can confuse with real…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Qixin Hu , Junfei Xiao , Yixiong Chen , Shuwen Sun , Jie-Neng Chen , Alan Yuille , Zongwei Zhou

We demonstrate that AI models can accurately segment liver tumors without the need for manual annotation by using synthetic tumors in CT scans. Our synthetic tumors have two intriguing advantages: (I) realistic in shape and texture, which…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Qixin Hu , Yixiong Chen , Junfei Xiao , Shuwen Sun , Jieneng Chen , Alan Yuille , Zongwei Zhou

Early detection and localization of pancreatic cancer can increase the 5-year survival rate for patients from 8.5% to 20%. Artificial intelligence (AI) can potentially assist radiologists in detecting pancreatic tumors at an early stage.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Bowen Li , Yu-Cheng Chou , Shuwen Sun , Hualin Qiao , Alan Yuille , Zongwei Zhou

Tumor synthesis can generate examples that AI often misses or over-detects, improving AI performance by training on these challenging cases. However, existing synthesis methods, which are typically unconditional -- generating images from…

Image and Video Processing · Electrical Eng. & Systems 2024-12-25 Xinran Li , Yi Shuai , Chen Liu , Qi Chen , Qilong Wu , Pengfei Guo , Dong Yang , Can Zhao , Pedro R. A. S. Bassi , Daguang Xu , Kang Wang , Yang Yang , Alan Yuille , Zongwei Zhou

AI-driven tumor analysis has garnered increasing attention in healthcare. However, its progress is significantly hindered by the lack of annotated tumor cases, which requires radiologists to invest a lot of effort in collecting and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Linshan Wu , Jiaxin Zhuang , Xuefeng Ni , Hao Chen

Tumor growth from a single transformed cancer cell up to a clinically apparent mass spans many spatial and temporal orders of magnitude. Implementation of cellular automata simulations of such tumor growth can be straightforward but…

Quantitative Methods · Quantitative Biology 2013-09-25 Jan Poleszczuk , Heiko Enderling

Pancreatic cancer remains one of the leading causes of cancer-related mortality worldwide. Precise segmentation of pancreatic tumors from medical images is a bottleneck for effective clinical decision-making. However, achieving a high…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Linkai Peng , Zheyuan Zhang , Gorkem Durak , Frank H. Miller , Alpay Medetalibeyoglu , Michael B. Wallace , Ulas Bagci

AI for tumor segmentation is limited by the lack of large, voxel-wise annotated datasets, which are hard to create and require medical experts. In our proprietary JHH dataset of 3,000 annotated pancreatic tumor scans, we found that AI…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Qi Chen , Xinze Zhou , Chen Liu , Hao Chen , Wenxuan Li , Zekun Jiang , Ziyan Huang , Yuxuan Zhao , Dexin Yu , Junjun He , Yefeng Zheng , Ling Shao , Alan Yuille , Zongwei Zhou

Tumor is a leading cause of death worldwide, with an estimated 10 million deaths attributed to tumor-related diseases every year. AI-driven tumor recognition unlocks new possibilities for more precise and intelligent tumor screening and…

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Due to privacy concerns, obtaining large datasets is challenging in medical image analysis, especially with 3D modalities like Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing generative models, developed to address…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jonghun Kim , Inye Na , Eun Sook Ko , Hyunjin Park

Artificial intelligence represents a new frontier in human medicine that could save more lives and reduce the costs, thereby increasing accessibility. As a consequence, the rate of advancement of AI in cancer medical imaging and more…

Early tumor detection save lives. Each year, more than 300 million computed tomography (CT) scans are performed worldwide, offering a vast opportunity for effective cancer screening. However, detecting small or early-stage tumors on these…

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

This study leverages synthetic data as a validation set to reduce overfitting and ease the selection of the best model in AI development. While synthetic data have been used for augmenting the training set, we find that synthetic data can…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Qixin Hu , Alan Yuille , Zongwei Zhou

The scarcity of annotated Magnetic Resonance Imaging (MRI) tumor data presents a major obstacle to accurate and automated tumor segmentation. While existing data synthesis methods offer promising solutions, they often suffer from key…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Nayu Dong , Townim Chowdhury , Hieu Phan , Mark Jenkinson , Johan Verjans , Zhibin Liao
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