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Large Language Models (LLMs) fine-tuned for specific domains exhibit strong performance; however, the underlying mechanisms by which this fine-tuning reshapes their parametric space are not well understood. Prior works primarily focus on…

Computation and Language · Computer Science 2025-10-13 Eshaan Tanwar , Deepak Nathani , William Yang Wang , Tanmoy Chakraborty

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural…

Computation and Language · Computer Science 2025-07-31 Miguel Rios

Multimodal large language models (MLLMs) fine-tuned with multimodal instruction datasets have demonstrated remarkable capabilities in multimodal tasks. However, fine-tuning all parameters of MLLMs has become challenging as they usually…

Computation and Language · Computer Science 2024-06-10 Xiongtao Zhou , Jie He , Yuhua Ke , Guangyao Zhu , Víctor Gutiérrez-Basulto , Jeff Z. Pan

The entry of large language models (LLMs) into research and commercial spaces has led to a trend of ever-larger models, with initial promises of generalisability, followed by a widespread desire to downsize and create specialised models…

Computation and Language · Computer Science 2024-02-19 Niall Taylor , Upamanyu Ghose , Omid Rohanian , Mohammadmahdi Nouriborji , Andrey Kormilitzin , David Clifton , Alejo Nevado-Holgado

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

In the realm of Medical Visual Language Models (Med-VLMs), the quest for universal efficient fine-tuning mechanisms remains paramount, especially given researchers in interdisciplinary fields are often extremely short of training resources,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Jiawei Chen , Dingkang Yang , Yue Jiang , Mingcheng Li , Jinjie Wei , Xiaolu Hou , Lihua Zhang

Large models such as Large Language Models (LLMs) and Vision Language Models (VLMs) have transformed artificial intelligence, powering applications in natural language processing, computer vision, and multimodal learning. However, fully…

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

While Large Language Models (LLMs) have demonstrated exceptional multitasking abilities, fine-tuning these models on downstream, domain-specific datasets is often necessary to yield superior performance on test sets compared to their…

Computation and Language · Computer Science 2024-03-15 Haoran Yang , Yumeng Zhang , Jiaqi Xu , Hongyuan Lu , Pheng Ann Heng , Wai Lam

While large language models (LLMs) often adopt finetuning to unlock their capabilities for downstream applications, our understanding on the inductive biases (especially the scaling properties) of different finetuning methods is still…

Computation and Language · Computer Science 2024-02-28 Biao Zhang , Zhongtao Liu , Colin Cherry , Orhan Firat

This paper delves into the pressing need in Parameter-Efficient Fine-Tuning (PEFT) for Large Language Models (LLMs). While LLMs possess remarkable capabilities, their extensive parameter requirements and associated computational demands…

Computation and Language · Computer Science 2023-11-23 Chengyu Wang , Junbing Yan , Wei Zhang , Jun Huang

Explorations in fine-tuning Vision-Language Models (VLMs), such as Low-Rank Adaptation (LoRA) from Parameter Efficient Fine-Tuning (PEFT), have made impressive progress. However, most approaches rely on explicit weight updates, overlooking…

Machine Learning · Computer Science 2025-12-30 Mingyuan Zhang , Yue Bai , Yifan Wang , Yiyang Huang , Yun Fu

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

The advancement of Large Language Models (LLMs) for domain applications in fields such as materials science and engineering depends on the development of fine-tuning strategies that adapt models for specialized, technical capabilities. In…

Computation and Language · Computer Science 2024-09-06 Wei Lu , Rachel K. Luu , Markus J. Buehler

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

When using supervised fine-tuning (SFT) to adapt large language models (LLMs) to specific domains, a significant challenge arises: should we use the entire SFT dataset for fine-tuning? Common practice often involves fine-tuning directly on…

Computation and Language · Computer Science 2025-05-26 Xiang Liu , Zhaoxiang Liu , Peng Wang , Kohou Wang , Huan Hu , Kai Wang , Shiguo Lian

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

Artificial intelligence (AI) technology has advanced rapidly in recent years, with large language models (LLMs) emerging as a significant breakthrough. LLMs are increasingly making an impact across various industries, with the medical field…

Artificial Intelligence · Computer Science 2025-09-24 Zhiyu Kan , Wensheng Gan , Zhenlian Qi , Philip S. Yu

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny
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