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The Segment Anything Model (SAM) represents a significant breakthrough into foundation models for computer vision, providing a large-scale image segmentation model. However, despite SAM's zero-shot performance, its segmentation masks lack…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Xianjie Liu , Keren Fu , Yao Jiang , Qijun Zhao

The recently introduced Segment Anything Model (SAM) combines a clever architecture and large quantities of training data to obtain remarkable image segmentation capabilities. However, it fails to reproduce such results for…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Tal Shaharabany , Aviad Dahan , Raja Giryes , Lior Wolf

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

Accurate segmentation of medical images is fundamental to tumor diagnosis and treatment planning. SAM-based interactive segmentation has gained attention for its strong generalization, but most methods follow a single-point-to-single-object…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Jierui Qu , Jianchun Zhao

Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…

Medical Physics · Physics 2024-12-05 Amirhosein Toosi , Sara Harsini , François Bénard , Carlos Uribe , Arman Rahmim

Segment Anything Model (SAM) has recently achieved amazing results in the field of natural image segmentation. However, it is not effective for medical image segmentation, owing to the large domain gap between natural and medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Zhengzheng Tu , Le Gu , Xixi Wang , Bo Jiang

In this study, we evaluate the performance of the Segment Anything Model (SAM) in clinical radiotherapy. Our results indicate that SAM's 'segment anything' mode can achieve clinically acceptable segmentation results in most organs-at-risk…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Lian Zhang , Zhengliang Liu , Lu Zhang , Zihao Wu , Xiaowei Yu , Jason Holmes , Hongying Feng , Haixing Dai , Xiang Li , Quanzheng Li , Dajiang Zhu , Tianming Liu , Wei Liu

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yanwu Yang , Guinan Su , Jiesi Hu , Francesco Sammarco , Jonas Geiping , Thomas Wolfers

Accurate segmentation of ovarian tumors from medical images is crucial for early diagnosis, treatment planning, and patient management. However, the diverse morphological characteristics and heterogeneous appearances of ovarian tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Yifan Gao , Wei Xia , Wenkui Wang , Xin Gao

The Segment Anything Model (SAM) is a foundational model for image segmentation tasks, known for its strong generalization across diverse applications. However, its impressive performance comes with significant computational and resource…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Xiaorui Sun , Jun Liu , Heng Tao Shen , Xiaofeng Zhu , Ping Hu

The Segment Anything Model (SAM) has achieved a notable success in two-dimensional image segmentation in natural images. However, the substantial gap between medical and natural images hinders its direct application to medical image…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Quan Quan , Fenghe Tang , Zikang Xu , Heqin Zhu , S. Kevin Zhou

The development of 2D foundation models for image segmentation has been significantly advanced by the Segment Anything Model (SAM). However, achieving similar success in 3D models remains a challenge due to issues such as non-unified data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-04 Yuchen Zhou , Jiayuan Gu , Tung Yen Chiang , Fanbo Xiang , Hao Su

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

Image segmentation is a critical enabler for tasks ranging from medical diagnostics to autonomous driving. However, the correct segmentation semantics - where are boundaries located? what segments are logically similar? - change depending…

TomoSAM has been developed to integrate the cutting-edge Segment Anything Model (SAM) into 3D Slicer, a highly capable software platform used for 3D image processing and visualization. SAM is a promptable deep learning model that is able to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Federico Semeraro , Alexandre Quintart , Sergio Fraile Izquierdo , Joseph C. Ferguson

Semi-supervised learning has attracted much attention due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods, which is especially important for medical image segmentation which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yichi Zhang , Jin Yang , Yuchen Liu , Yuan Cheng , Yuan Qi

Segment Anything Model (SAM) has achieved impressive results for natural image segmentation with input prompts such as points and bounding boxes. Its success largely owes to massive labeled training data. However, directly applying SAM to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Jin Ye , Junlong Cheng , Jianpin Chen , Zhongying Deng , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Min Zhu , Shaoting Zhang , Junjun He , Yu Qiao

Medical image segmentation plays a crucial role in clinical diagnosis and treatment planning, where accurate boundary delineation is essential for precise lesion localization, organ identification, and quantitative assessment. In recent…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Peiting Tian , Xi Chen , Haixia Bi , Fan Li

Segment anything model (SAM) demonstrates strong generalization ability on natural image segmentation. However, its direct adaptation in medical image segmentation tasks shows significant performance drops. It also requires an excessive…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Heng Guo , Jianfeng Zhang , Jiaxing Huang , Tony C. W. Mok , Dazhou Guo , Ke Yan , Le Lu , Dakai Jin , Minfeng Xu
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