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Variational quantum circuits (VQCs) hold promise for quantum machine learning but face challenges in expressivity, trainability, and noise resilience. We propose VQC-MLPNet, a hybrid architecture where a VQC generates the first-layer…

Quantum Physics · Physics 2025-11-06 Jun Qi , Chao-Han Yang , Pin-Yu Chen , Min-Hsiu Hsieh

Crime pattern analysis is critical for law enforcement and predictive policing, yet the surge in criminal activities from rapid urbanization creates high-dimensional, imbalanced datasets that challenge traditional classification methods.…

Machine Learning · Computer Science 2026-04-14 Niloy Das , Apurba Adhikary , Sheikh Salman Hassan , Yu Qiao , Zhu Han , Tharmalingam Ratnarajah , Choong Seon Hong

Graph-structured data commonly arise in many real-world applications, and this extends naturally into the quantum setting, where quantum data with inherent graph structures are frequently generated by typical quantum data sources. However,…

Quantum Physics · Physics 2025-08-27 Yanying Liang , Sile Tang , Zhehao Yi , Haozhen Situ , Zhu-Jun Zheng

Accurate prediction of residue-level pKa values is essential for understanding protein function, stability, and reactivity. While existing resources such as DeepKaDB and CpHMD-derived datasets provide valuable training data, their…

Chemical Physics · Physics 2026-03-13 Van Le , Tan Le

Hybrid quantum and classical learning aims to couple quantum feature maps with the robustness of classical neural networks, yet most architectures treat the quantum circuit as an isolated feature extractor and merge its measurements with…

Machine Learning · Computer Science 2025-12-23 Azadeh Alavi , Fatemeh Kouchmeshki , Abdolrahman Alavi

Quantum machine learning has emerged as a promising application domain for near-term quantum hardware, particularly through hybrid quantum-classical models that leverage both classical and quantum processing. Although numerous hybrid…

Quantum Physics · Physics 2026-01-09 Dominik Freinberger , Philipp Moser

Anomaly detection is a vital technique for exploring signatures of new physics Beyond the Standard Model (BSM) at the Large Hadron Collider (LHC). The vast number of collisions generated by the LHC demands sophisticated deep learning…

High Energy Physics - Phenomenology · Physics 2024-11-18 A. Hammad , Mihoko M. Nojiri , Masahito Yamazaki

The field of drug discovery hinges on the accurate prediction of binding affinity between prospective drug molecules and target proteins, especially when such proteins directly influence disease progression. However, estimating binding…

We consider the prediction of the Hamiltonian matrix, which finds use in quantum chemistry and condensed matter physics. Efficiency and equivariance are two important, but conflicting factors. In this work, we propose a SE(3)-equivariant…

Machine Learning · Computer Science 2023-11-09 Haiyang Yu , Zhao Xu , Xiaofeng Qian , Xiaoning Qian , Shuiwang Ji

Protein-ligand binding affinity is critical in drug discovery, but experimentally determining it is time-consuming and expensive. Artificial intelligence (AI) has been used to predict binding affinity, significantly accelerating this…

Emerging Technologies · Computer Science 2025-09-16 Seon-Geun Jeong , Kyeong-Hwan Moon , Won-Joo Hwang

Hybrid quantum-classical neural networks represent a promising frontier in the search for improved machine learning models. This thesis explores the integration of quantum layers within classical convolutional neural network architectures,…

Quantum Physics · Physics 2025-07-18 Silvie Illésová

With the rapid advance of quantum machine learning, several proposals for the quantum-analogue of convolutional neural network (CNN) have emerged. In this work, we benchmark fully parameterized quantum convolutional neural networks (QCNNs)…

Quantum Physics · Physics 2022-02-14 Tak Hur , Leeseok Kim , Daniel K. Park

We present three multi-scale similarity learning architectures, or DeepSim networks. These models learn pixel-level matching with a contrastive loss and are agnostic to the geometry of the considered scene. We establish a middle ground…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Mohamed Ali Chebbi , Ewelina Rupnik , Marc Pierrot-Deseilligny , Paul Lopes

Classical Random Neural Networks (RNNs) have demonstrated effective applications in decision making, signal processing, and image recognition tasks. However, their implementation has been limited to deterministic digital systems that output…

Quantum Physics · Physics 2022-03-07 Debanjan Konar , Erol Gelenbe , Soham Bhandary , Aditya Das Sarma , Attila Cangi

Image classification must work for autonomous vehicles (AV) operating on public roads, and actions performed based on image misclassification can have serious consequences. Traffic sign images can be misclassified by an adversarial attack…

This work addresses the challenge of enabling practitioners without quantum expertise to transition from classical to hybrid quantum-classical machine learning workflows. We propose a three-stage framework: starting with a classical…

This paper investigates quantum machine learning to optimize the beamforming in a multiuser multiple-input single-output downlink system. We aim to combine the power of quantum neural networks and the success of classical deep neural…

Information Theory · Computer Science 2024-08-12 Juping Zhang , Gan Zheng , Toshiaki Koike-Akino , Kai-Kit Wong , Fraser Burton

A major challenge in quantum information is characterizing entanglement, for which entanglement witnesses offer effective means of detecting quantum correlations. We introduce a hybrid quantum-classical framework that learns a nonlinear…

Quantum Physics · Physics 2025-09-09 Mohammad Rezaei Shokou , Hossein Davoodi Yeganeh

Sparse coding provides a versatile framework for efficiently capturing and representing crucial data (information) concisely, which plays an essential role in various computer science fields, including data compression, feature extraction,…

Quantum Physics · Physics 2024-11-15 Xun Ji , Qin Liu , Shang Huang , Andi Chen , Shengjun Wu

While quantum architectures are still under development, when available, they will only be able to process quantum data when machine learning algorithms can only process numerical data. Therefore, in the issues of classification or…

Machine Learning · Computer Science 2025-12-16 Rafal Potempa , Sebastian Porebski