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The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

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Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

Binary code summarization, while invaluable for understanding code semantics, is challenging due to its labor-intensive nature. This study delves into the potential of large language models (LLMs) for binary code comprehension. To this end,…

Cryptography and Security · Computer Science 2023-12-18 Xin Jin , Jonathan Larson , Weiwei Yang , Zhiqiang Lin

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

Large Language Models (LLMs) like the GPT and LLaMA families have demonstrated exceptional capabilities in capturing and condensing critical contextual information and achieving state-of-the-art performance in the summarization task.…

Computation and Language · Computer Science 2023-11-06 Prakamya Mishra , Zonghai Yao , Shuwei Chen , Beining Wang , Rohan Mittal , Hong Yu

Given a document in a source language, cross-lingual summarization (CLS) aims to generate a summary in a different target language. Recently, the emergence of Large Language Models (LLMs), such as GPT-3.5, ChatGPT and GPT-4, has attracted…

Computation and Language · Computer Science 2023-10-25 Jiaan Wang , Yunlong Liang , Fandong Meng , Beiqi Zou , Zhixu Li , Jianfeng Qu , Jie Zhou

Reliable evaluation of large language model (LLM)-generated summaries remains an open challenge, particularly across heterogeneous domains and document lengths. We conduct a comprehensive meta-evaluation of 14 automatic summarization…

Computation and Language · Computer Science 2026-04-29 Huyen Nguyen , Haoxuan Zhang , Yang Zhang , Junhua Ding , Haihua Chen

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

Large language models (LLMs) have shown promise in safety-critical applications such as healthcare, yet the ability to quantify performance has lagged. An example of this challenge is in evaluating a summary of the patient's medical record.…

Computation and Language · Computer Science 2024-11-13 Elliot Schumacher , Daniel Rosenthal , Dhruv Naik , Varun Nair , Luladay Price , Geoffrey Tso , Anitha Kannan

Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Computation and Language · Computer Science 2025-09-08 Maya Kruse , Shiyue Hu , Nicholas Derby , Yifu Wu , Samantha Stonbraker , Bingsheng Yao , Dakuo Wang , Elizabeth Goldberg , Yanjun Gao

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Computation and Language · Computer Science 2026-02-20 Heloisa Oss Boll , Antonio Oss Boll , Leticia Puttlitz Boll , Ameen Abu Hanna , Iacer Calixto

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

This work presents a dynamic vocabulary adaptation strategy, MEDVOC, for fine-tuning pre-trained language models (PLMs) like BertSumAbs, BART, and PEGASUS for improved medical text summarization. In contrast to existing domain adaptation…

Computation and Language · Computer Science 2024-08-20 Gunjan Balde , Soumyadeep Roy , Mainack Mondal , Niloy Ganguly

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

Discharge summaries in Electronic Health Records (EHRs) are crucial for clinical decision-making, but their length and complexity make information extraction challenging, especially when dealing with accumulated summaries across multiple…

Computation and Language · Computer Science 2024-11-12 Sunjun Kweon , Jiyoun Kim , Heeyoung Kwak , Dongchul Cha , Hangyul Yoon , Kwanghyun Kim , Jeewon Yang , Seunghyun Won , Edward Choi