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To achieve high-quality results, diffusion models must be trained on large datasets. This can be notably prohibitive for models in specialized domains, such as computational pathology. Conditioning on labeled data is known to help in…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Srikar Yellapragada , Alexandros Graikos , Prateek Prasanna , Tahsin Kurc , Joel Saltz , Dimitris Samaras

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Kanishk Choudhary

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

Automatic report generation has arisen as a significant research area in computer-aided diagnosis, aiming to alleviate the burden on clinicians by generating reports automatically based on medical images. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jun Li , Tongkun Su , Baoliang Zhao , Faqin Lv , Qiong Wang , Nassir Navab , Ying Hu , Zhongliang Jiang

Recent advances in radiology report generation (RRG) have been driven by large paired image-text datasets; however, progress in neuro-oncology has been limited due to a lack of open paired image-report datasets. Here, we introduce BTReport,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Juampablo E. Heras Rivera , Dickson T. Chen , Tianyi Ren , Daniel K. Low , Asma Ben Abacha , Alberto Santamaria-Pang , Mehmet Kurt

Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan

Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Shivam Kumar , Samrat Chatterjee

Whole-slide images (WSIs) present a fundamental challenge for computational pathology due to their extreme resolution, multi-scale heterogeneity, and the requirement for clinically reliable interpretation. Although recent pathology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Suryakant Singh , Saarthak Kapse , Joel Saltz , Prateek Prasanna

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

Medical domain automated text generation is an active area of research and development; however, evaluating the clinical quality of generated reports remains a challenge, especially in instances where domain-specific metrics are lacking,…

Computation and Language · Computer Science 2025-09-23 Yunsoo Kim , Michal W. S. Ong , Alex Shavick , Honghan Wu , Adam P. Levine

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to…

Radiology report generation (RRG) has emerged as a promising approach to alleviate radiologists' workload and reduce human errors by automatically generating diagnostic reports from medical images. A key challenge in RRG is achieving…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Yucheng Chen , Yang Yu , Yufei Shi , Conghao Xiong , Xulei Yang , Si Yong Yeo

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Richard J. Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Jana Lipkova , Muhammad Shaban , Maha Shady , Mane Williams , Bumjin Joo , Zahra Noor , Faisal Mahmood

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Jinpeng Lu , Jingyun Chen , Linghan Cai , Songhan Jiang , Yongbing Zhang