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The spatial linear mixed model (SLMM) consists of fixed and spatial random effects that may be linearly dependent. Partially motivated as a means to address potential issues with confounding, the Restricted spatial regression (RSR) model…

Methodology · Statistics 2026-03-24 Jonathan R. Bradley

The issue of spatial confounding between the spatial random effect and the fixed effects in regression analyses has been identified as a concern in the statistical literature. Multiple authors have offered perspectives and potential…

Methodology · Statistics 2023-01-18 Kori Khan , Catherine A. Calder

Causal inference in spatial domains faces two intertwined challenges: (1) unmeasured spatial factors, such as weather, air pollution, or mobility, that confound treatment and outcome, and (2) interference from nearby treatments that violate…

Machine Learning · Computer Science 2025-10-13 Ayush Khot , Miruna Oprescu , Maresa Schröder , Ai Kagawa , Xihaier Luo

Spatial confounding between the spatial random effects and fixed effects covariates has been recently discovered and showed that it may bring misleading interpretation to the model results. Solutions to alleviate this problem are based on…

Methodology · Statistics 2016-05-17 Marcos O. Prates , Erica C. Rodrigues , Renato M. Assunção

We develop Bayesian nonparametric models for spatially indexed data of mixed type. Our work is motivated by challenges that occur in environmental epidemiology, where the usual presence of several confounding variables that exhibit complex…

Methodology · Statistics 2014-10-17 Georgios Papageorgiou , Sylvia Richardson , Nicky Best

A new statistical model designed for regression analysis with a sparse design matrix is proposed. This new model utilizes the positions of the limited non-zero elements in the design matrix to decompose the regression model into…

Applications · Statistics 2022-01-17 Hsien-Wei Chen

Spatial interference and spatial confounding are two major issues inhibiting precise causal estimates when dealing with observational spatial data. Moreover, the definition and interpretation of spatial confounding remain arguable in the…

Methodology · Statistics 2026-02-04 Isqeel Ogunsola , Olatunji Johnson

Semi-structured regression models enable the joint modeling of interpretable structured and complex unstructured feature effects. The structured model part is inspired by statistical models and can be used to infer the input-output…

Machine Learning · Computer Science 2024-01-24 Daniel Dold , David Rügamer , Beate Sick , Oliver Dürr

Increasingly large parameter spaces, used to more accurately model precision observables in physics, can paradoxically lead to large deviations in the inferred parameters of interest -- a bias known as volume projection effects -- when…

Cosmology and Nongalactic Astrophysics · Physics 2025-07-29 Alexander Reeves , Pierre Zhang , Henry Zheng

Spatial confounding poses a significant challenge in scientific studies involving spatial data, where unobserved spatial variables can influence both treatment and outcome, possibly leading to spurious associations. To address this problem,…

Machine Learning · Computer Science 2024-12-04 Mauricio Tec , Ana Trisovic , Michelle Audirac , Sophie Woodward , Jie Kate Hu , Naeem Khoshnevis , Francesca Dominici

We investigate spatial confounding in the presence of multivariate disease dependence. In the "analysis model perspective" of spatial confounding, adding a spatially dependent random effect can lead to significant variance inflation of the…

Methodology · Statistics 2026-02-13 Kyle Lin Wu , Sudipto Banerjee

The spatial random-effects model is flexible in modeling spatial covariance functions, and is computationally efficient for spatial prediction via fixed rank kriging. However, the success of this model depends on an appropriate set of basis…

Methodology · Statistics 2015-04-23 ShengLi Tzeng , Hsin-Cheng Huang

Spatial regression of random fields based on potentially biased sensing information is proposed in this paper. One major concern in such applications is that since it is not known a-priori what the accuracy of the collected data from each…

Signal Processing · Electrical Eng. & Systems 2020-09-04 Qikun Xiang , Ido Nevat , Gareth W. Peters

1 - Spatial confounding is a phenomenon that has been studied extensively in recent years in the statistical literature to describe and mitigate apparent inconsistencies between the results obtained by regression models with and without…

Parametric Bayesian modeling offers a powerful and flexible toolbox for machine learning. Yet the model, however detailed, may still be wrong, and this can make inferences untrustworthy. In this paper we introduce a new class of…

Methodology · Statistics 2026-04-03 Bohan Wu , Eli N. Weinstein , Sohrab Salehi , Yixin Wang , David M. Blei

The concept of spatial confounding is closely connected to spatial regression, although no general definition has been established. A generally accepted idea of spatial confounding in spatial regression models is the change in fixed effects…

Methodology · Statistics 2022-12-27 A. Urdangarin , T. Goicoa , M. D. Ugarte

Confounding can lead to spurious associations. Typically, one must observe confounders in order to adjust for them, but in high-dimensional settings, recent research has shown that it becomes possible to adjust even for unobserved…

Methodology · Statistics 2025-10-07 Yujing Lu , Patrick Breheny

Functional data are frequently accompanied by a parametric template that describes the typical shapes of the functions. However, these parametric templates can incur significant bias, which undermines both utility and interpretability. To…

Methodology · Statistics 2022-05-18 Daniel R. Kowal , Antonio Canale

We consider the problem of precision matrix estimation where, due to extraneous confounding of the underlying precision matrix, the data are independent but not identically distributed. While such confounding occurs in many scientific…

Machine Learning · Statistics 2019-07-01 Sinong Geng , Mladen Kolar , Oluwasanmi Koyejo

Regression for spatially dependent outcomes poses many challenges, for inference and for computation. Non-spatial models and traditional spatial mixed-effects models each have their advantages and disadvantages, making it difficult for…

Methodology · Statistics 2017-08-02 John Hughes