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In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Whole Slide Image (WSI) classification poses unique challenges due to the vast image size and numerous non-informative regions, which introduce noise and cause data imbalance during feature aggregation. To address these issues, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Jianwei Zhao , Xin Li , Fan Yang , Qiang Zhai , Ao Luo , Yang Zhao , Hong Cheng , Huazhu Fu

Most meta-learning approaches assume the existence of a very large set of labeled data available for episodic meta-learning of base knowledge. This contrasts with the more realistic continual learning paradigm in which data arrives…

Computer Vision and Pattern Recognition · Computer Science 2021-11-12 Kai Wang , Xialei Liu , Andy Bagdanov , Luis Herranz , Shangling Jui , Joost van de Weijer

Knowledge distillation has been applied to various tasks successfully. The current distillation algorithm usually improves students' performance by imitating the output of the teacher. This paper shows that teachers can also improve…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Zhendong Yang , Zhe Li , Mingqi Shao , Dachuan Shi , Zehuan Yuan , Chun Yuan

We present a novel class incremental learning approach based on deep neural networks, which continually learns new tasks with limited memory for storing examples in the previous tasks. Our algorithm is based on knowledge distillation and…

Machine Learning · Computer Science 2022-04-05 Minsoo Kang , Jaeyoo Park , Bohyung Han

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Lack of specialized data makes building a multi-domain neural machine translation tool challenging. Although emerging literature dealing with low resource languages starts to show promising results, most state-of-the-art models used…

Computation and Language · Computer Science 2020-04-17 Idriss Mghabbar , Pirashanth Ratnamogan

Traditionally, distillation has been used to train a student model to emulate the input/output functionality of a teacher. A more useful goal than emulation, yet under-explored, is for the student to learn feature representations that…

Computer Vision and Pattern Recognition · Computer Science 2021-07-19 Zhizhong Li , Avinash Ravichandran , Charless Fowlkes , Marzia Polito , Rahul Bhotika , Stefano Soatto

Prompt tuning, which involves training a small set of parameters, effectively enhances the pre-trained Vision-Language Models (VLMs) to downstream tasks. However, they often come at the cost of flexibility and adaptability when the tuned…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Mushui Liu , Bozheng Li , Yunlong Yu

Resource-constrained perception systems such as edge computing and vision-for-robotics require vision models to be both accurate and lightweight in computation and memory usage. While knowledge distillation is a proven strategy to enhance…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Shengcao Cao , Mengtian Li , James Hays , Deva Ramanan , Yi-Xiong Wang , Liang-Yan Gui

Computational methods on analyzing Whole Slide Images (WSIs) enable early diagnosis and treatments by supporting pathologists in detection and classification of tumors. However, the extremely high resolution of WSIs makes end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Umar Marikkar , Muhammad Awais , Sara Atito

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

In the application of Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) classification, attention mechanisms often focus on a subset of discriminative instances, which are closely linked to overfitting. To mitigate…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yunlong Zhang , Honglin Li , Yuxuan Sun , Sunyi Zheng , Chenglu Zhu , Lin Yang

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Le Feng , Li Xiao

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Jiaxiang Gou , Luping Ji , Pei Liu , Mao Ye

Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images (WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL methods primarily focus on improving the feature…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Tiancheng Lin , Zhimiao Yu , Hongyu Hu , Yi Xu , Chang Wen Chen

Masked image modeling has demonstrated great potential to eliminate the label-hungry problem of training large-scale vision Transformers, achieving impressive performance on various downstream tasks. In this work, we propose a unified view…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Zhiliang Peng , Li Dong , Hangbo Bao , Qixiang Ye , Furu Wei

Multi-view representation learning aims to derive robust representations that are both view-consistent and view-specific from diverse data sources. This paper presents an in-depth analysis of existing approaches in this domain, highlighting…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Guanzhou Ke , Bo Wang , Xiaoli Wang , Shengfeng He

Knowledge distillation addresses the problem of transferring knowledge from a teacher model to a student model. In this process, we typically have multiple types of knowledge extracted from the teacher model. The problem is to make full use…

Computation and Language · Computer Science 2023-02-02 Chenglong Wang , Yi Lu , Yongyu Mu , Yimin Hu , Tong Xiao , Jingbo Zhu
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