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Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

This thesis aims to investigate the feasibility of knowledge transfer between neural networks for medical image segmentation tasks, specifically focusing on the transfer from a larger multi-task "Teacher" network to a smaller "Student"…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Risab Biswas

In this paper, we propose a novel interpretation method tailored to histological Whole Slide Image (WSI) processing. A Deep Neural Network (DNN), inspired by Bag-of-Features models is equipped with a Multiple Instance Learning (MIL) branch…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Magdalini Paschali , Muhammad Ferjad Naeem , Walter Simson , Katja Steiger , Martin Mollenhauer , Nassir Navab

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

State-of-the-art CNN based recognition models are often computationally prohibitive to deploy on low-end devices. A promising high level approach tackling this limitation is knowledge distillation, which let small student model mimic…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Tao Wang , Li Yuan , Xiaopeng Zhang , Jiashi Feng

In incremental classification tasks for hyperspectral images, catastrophic forgetting is an unavoidable challenge. While memory recall methods can mitigate this issue, they heavily rely on samples from old categories. This paper proposes a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Songfeng Zhu

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

Multiple instance learning (MIL) is the standard approach for whole-slide image (WSI) classification and survival prediction, where attention-based models ag gregate patch features into slide-level predictions. These models treat attention…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiangyu Li , Ran Su

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

High-quality annotation of fine-grained visual categories demands great expert knowledge, which is taxing and time consuming. Alternatively, learning fine-grained visual representation from enormous unlabeled images (e.g., species, brands)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Qi Bi , Wei Ji , Jingjun Yi , Haolan Zhan , Gui-Song Xia

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Representation learning has been evolving from traditional supervised training to Contrastive Learning (CL) and Masked Image Modeling (MIM). Previous works have demonstrated their pros and cons in specific scenarios, i.e., CL and supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Bowen Shi , Xiaopeng Zhang , Yaoming Wang , Jin Li , Wenrui Dai , Junni Zou , Hongkai Xiong , Qi Tian

Recent advances in deep learning has lead to rapid developments in the field of image retrieval. However, the best performing architectures incur significant computational cost. Recent approaches tackle this issue using knowledge…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Zakaria Laskar , Juho Kannala

As the development of neural networks, more and more deep neural networks are adopted in various tasks, such as image classification. However, as the huge computational overhead, these networks could not be applied on mobile devices or…

Computer Vision and Pattern Recognition · Computer Science 2019-12-03 Yunteng Luan , Hanyu Zhao , Zhi Yang , Yafei Dai

Incremental learning targets at achieving good performance on new categories without forgetting old ones. Knowledge distillation has been shown critical in preserving the performance on old classes. Conventional methods, however,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Peng Zhou , Long Mai , Jianming Zhang , Ning Xu , Zuxuan Wu , Larry S. Davis

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song