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Interpretability is essential for machine learning algorithms in high-stakes application fields such as medical image analysis. However, high-performing black-box neural networks do not provide explanations for their predictions, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner

The need for transparency of predictive systems based on Machine Learning algorithms arises as a consequence of their ever-increasing proliferation in the industry. Whenever black-box algorithmic predictions influence human affairs, the…

Machine Learning · Computer Science 2020-02-11 Kacper Sokol , Peter Flach

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Deep neural networks have achieved remarkable success in various challenging tasks. However, the black-box nature of such networks is not acceptable to critical applications, such as healthcare. In particular, the existence of adversarial…

Machine Learning · Computer Science 2019-09-12 Shaeke Salman , Seyedeh Neelufar Payrovnaziri , Xiuwen Liu , Pablo Rengifo-Moreno , Zhe He

Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Chuang Niu , Ge Wang

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Recently, artificial intelligence and machine learning in general have demonstrated remarkable performances in many tasks, from image processing to natural language processing, especially with the advent of deep learning. Along with…

Machine Learning · Computer Science 2020-10-23 Erico Tjoa , Cuntai Guan

With the onset of the COVID-19 pandemic, ultrasound has emerged as an effective tool for bedside monitoring of patients. Due to this, a large amount of lung ultrasound scans have been made available which can be used for AI based diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Gautam Rajendrakumar Gare , Hai V. Tran , Bennett P deBoisblanc , Ricardo Luis Rodriguez , John Michael Galeotti

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

The full acceptance of Deep Learning (DL) models in the clinical field is rather low with respect to the quantity of high-performing solutions reported in the literature. Particularly, end users are reluctant to rely on the rough…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Benjamin Lambert , Florence Forbes , Alan Tucholka , Senan Doyle , Harmonie Dehaene , Michel Dojat

We are used to the availability of big data generated in nearly all fields of science as a consequence of technological progress. However, the analysis of such data possess vast challenges. One of these relates to the explainability of…

Artificial Intelligence · Computer Science 2022-09-14 Frank Emmert-Streib , Olli Yli-Harja , Matthias Dehmer

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Abdelbaki Souid , Mohamed Hamroun , Soufiene Ben Othman , Hedi Sakli , Naceur Abdelkarim

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

As AI systems become more embedded in everyday life, the development of fair and unbiased models becomes more critical. Considering the social impact of AI systems is not merely a technical challenge but a moral imperative. As evidenced in…

Machine Learning · Computer Science 2025-10-03 Aida Tayebi , Ali Khodabandeh Yalabadi , Mehdi Yazdani-Jahromi , Ozlem Ozmen Garibay

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

The field of machine learning has seen tremendous progress in recent years, with deep learning models delivering exceptional performance across a range of tasks. However, these models often come at the cost of interpretability, as they…

Machine Learning · Computer Science 2024-01-08 Shun Liu

In visual object classification, humans often justify their choices by comparing objects to prototypical examples within that class. We may therefore increase the interpretability of deep learning models by imbuing them with a similar style…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Ayodeji Ijishakin , Ahmed Abdulaal , Adamos Hadjivasiliou , Sophie Martin , James Cole