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Transported chemical reactions in unsaturated porous media are relevant across a range of environmental and industrial applications. Continuum scale dispersive models are often based on equivalent parameters derived from analogy with…

The liquid-liquid phase separation of biomolecules is an important process for intracellular organization. Biomolecular sequence combinatorics leads to a large variety of proteins and nucleic acids which can interact to form a diversity of…

Soft Condensed Matter · Physics 2025-08-27 Aria S. Chaderjian , Sam Wilken , Omar A. Saleh

Quenched or frozen-in structural disorder is ubiquitous in real experimental systems. Much of the progress is achieved in understanding the phase separation of such systems using the diffusion-driven coarsening in Ising model with quenched…

Soft Condensed Matter · Physics 2023-08-15 Rounak Bhattacharyya , Bhaskar Sen Gupta

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

We study the effect of confinement on diffusion limited bimolecular reactions within a lattice model where a small number of reactants diffuse amongst a much larger number of inert particles. When the number of inert particles is held…

Soft Condensed Matter · Physics 2013-05-29 Jeremy D. Schmit , Ercan Kamber , Jané Kondev

Phase separation is as familiar as watching vinegar separating from oil in vinegrette. The observation that phase separation of proteins and nucleic acids is widespread in living cells has opened an entire field of research into the…

Soft Condensed Matter · Physics 2022-06-16 Davide Michieletto , Mattia Marenda

Phase separation into compositionally and physically distinct domains is ubiquitous in (non)living matter ranging from alloys and emulsions to biomolecular condensates in cells. The organization of these domains can be controlled, for…

Soft Condensed Matter · Physics 2026-03-31 Andriy Goychuk

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

Biological Physics · Physics 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

Discrete element method simulations of confined bidisperse granular shear flows elucidate the balance between diffusion and segregation that can lead to either mixed or segregated states, depending on confining pressure. Results indicate…

Soft Condensed Matter · Physics 2018-09-24 Alexander M. Fry , Paul B. Umbanhowar , Julio M. Ottino , Richard M. Lueptow

The interaction lifetimes between condensate-forming biomolecules can dictate both the specificity of the condensate-forming species as well as the fluidity and exchange dynamics of these condensates. Using a heuristic modeling approach, we…

Soft Condensed Matter · Physics 2025-06-30 Bhanjan Debnath , Parag Katira

Embedding sequential computations in biochemical environments is challenging because the computations are carried out by chemical reactions, which are inherently disordered. In this paper we apply modular design to specific calculations…

Molecular Networks · Quantitative Biology 2024-01-05 Xiaopeng Shi , Chuanhou Gao , Denis Dochain

The chemical reactions are very complex, and include oscillation, condensation, catalyst and self-organization, etc. In these case changes of entropy may increase or decrease. The second law of thermodynamics is based on an isolated system…

General Physics · Physics 2008-07-03 Yi-Fang Chang

In chemical reactions, the interplay between coherent evolution and dissipation is central to determining key properties such as the rate and yield. Of particular interest are cases where two potential energy surfaces cross at features…

Regulation of multiple reaction modules is quite common in molecular computation and deep learning networks construction through chemical reactions, as is always a headache for that sequential execution of modules goes against the…

Dynamical Systems · Mathematics 2022-11-08 Xiaopeng Shi , Chuanhou Gao , Denis Dochain

Co-existence of phase segregation and \emph{interconversion} or \emph{isomerization} reaction among molecular species leads to fascinating structure formation in biological and chemical world. Using Monte Carlo simulations of the prototype…

Statistical Mechanics · Physics 2023-08-07 Shubham Thwal , Suman Majumder

Biphasic chemical reactions compartmentalized in small droplets offer advantages, such as streamlined procedures for chemical analysis, enhanced chemical reaction efficiency and high specificity of conversion. In this work, we…

Soft Condensed Matter · Physics 2020-07-10 Zhengxin Li , Akihito Kiyama , Hongbo Zeng , Detlef Lohse , Xuehua Zhang

In a companion paper, we put forth a thermodynamic model for complex formation via a chemical reaction involving multiple macromolecular species, which may subsequently undergo liquid-liquid phase separation and a further transition into a…

Biological Physics · Physics 2024-07-26 Ruoyao Zhang , Sheng Mao , Mikko P. Haataja

Self-assembly processes in biological and synthetic biomolecular systems are often governed by the spatial separation of biochemical processes. While previous work has focused on optimizing self-assembly through fine-tuned reaction…

Biological Physics · Physics 2026-02-17 Severin Angerpointner , Richard Swiderski , Erwin Frey

The relative phase between two uncoupled BE condensates tends to attain a specific value when the phase is measured. This can be done by observing their decay products in interference. We discuss exactly solvable models for this process in…

Quantum Physics · Physics 2009-11-10 H. L. Haroutyunyan , G. Nienhuis

Stochastic chemical systems with diffusion are modeled with a reaction-diffusion master equation. On a macroscopic level, the governing equation is a reaction-diffusion equation for the averages of the chemical species. On a mesoscopic…

Numerical Analysis · Mathematics 2009-03-06 Stefan Engblom , Lars Ferm , Andreas Hellander , Per Lötstedt
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