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We give an overview of the role of information theory in statistics, and particularly in biostatistics. We recall the basic quantities in information theory; entropy, cross-entropy, conditional entropy, mutual information and…

Statistics Theory · Mathematics 2015-11-04 Daniel Commenges

Estimating and quantifying uncertainty in unknown system parameters from limited data remains a challenging inverse problem in a variety of real-world applications. While many approaches focus on estimating constant parameters, a subset of…

Methodology · Statistics 2023-05-09 Andrea Arnold

We present a Hamiltonian approach for the wellknown Eigen model of the Darwin selection dynamics. Hamiltonization is carried out by means of the embedding of the population variable space, describing behavior of the system, into the space…

Biological Physics · Physics 2009-10-30 A. V. Shapovalov , E. V. Evdokimov

Existing theoretical models of evolution focus on the relative fitness advantages of different mutants in a population while the dynamic behavior of the population size is mostly left unconsidered. We here present a generic stochastic model…

Populations and Evolution · Quantitative Biology 2010-10-20 Anna Melbinger , Jonas Cremer , Erwin Frey

We try to establish a unified information theoretic approach to learning and to explore some of its applications. First, we define {\em predictive information} as the mutual information between the past and the future of a time series,…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Ilya Nemenman

Ecosystems dynamics is often considered as driven by a coupling of species' resource consumption and its population size dynamics. Such resource-population dynamics is captured by MacArthur-type models. One biologically relevant feature…

Populations and Evolution · Quantitative Biology 2023-07-10 Elena Bellavere , Christian H. S. Hamster , Joshua A. Dijksman

A novel optimization strategy, Info-Evo, is described, in which natural gradient search using nonparametric Fisher information is used to provide ongoing guidance to an evolutionary learning algorithm, so that the evolutionary process…

Neural and Evolutionary Computing · Computer Science 2021-03-09 Ben Goertzel

We propose a continuous model for evolutionary rate variation across sites and over the tree and derive exact transition probabilities under this model. Changes in rate are modelled using the CIR process, a diffusion widely used in…

Probability · Mathematics 2007-05-23 Thomas Lepage , Stephan Lawi , Paul Tupper , David Bryant

As mathematical model for the evolutionary equations of species the masterequation is choiced. Two formulations will be demonstrated to include the changes of parameters into the masterequation - that is, on the one hand, the formation of a…

Populations and Evolution · Quantitative Biology 2007-05-23 Ingrid Hartmann

We derive a connection between performance of estimators the performance of the ideal observer on related detection tasks. Specifically we show how Shannon Information for the task of detecting a change in a parameter is related to the…

Information Theory · Computer Science 2019-07-24 Eric Clarkson

Recently proposed methods in data subset selection, that is active learning and active sampling, use Fisher information, Hessians, similarity matrices based on gradients, and gradient lengths to estimate how informative data is for a…

Machine Learning · Computer Science 2022-11-08 Andreas Kirsch , Yarin Gal

Information criteria are an appropriate and widely used tool for solving model selection problems. However, different ways to use them exist, each leading to a more or less precise approximation of the sought model. In this paper, we mainly…

Statistics Theory · Mathematics 2007-06-13 Guilhem Coq , Olivier Alata , Marc Arnaudon , Christian Olivier

A major obstacle in analyzing the evolution of information exchange and processing is our insufficient understanding of the underlying signaling and decision-making biological mechanisms. For instance, it is unclear why are humans unique in…

Populations and Evolution · Quantitative Biology 2008-09-06 A. Feigel

Current experimental design techniques for dynamical systems often only incorporate measurement noise, while dynamical systems also involve process noise. To construct experimental designs we need to quantify their information content. The…

Methodology · Statistics 2026-03-24 Arno Strouwen , Bart M. Nicolaï , Peter Goos

In the fields of finance, engineering and sciences data mining/ machine learning has held an eminent position in predictive analysis. Complex algorithms and adaptive decision models have contributed towards streamlining research as well as…

Information Theory · Computer Science 2012-07-03 Indraneel Dabhade

Training Data Attribution (TDA) seeks to trace model predictions back to influential training examples, enhancing interpretability and safety. We formulate TDA as a Bayesian information-theoretic problem: subsets are scored by the…

Machine Learning · Computer Science 2026-04-10 Dharmesh Tailor , Nicolò Felicioni , Kamil Ciosek

Information theory is an outstanding framework to measure uncertainty, dependence and relevance in data and systems. It has several desirable properties for real world applications: it naturally deals with multivariate data, it can handle…

Machine Learning · Statistics 2024-10-30 Valero Laparra , J. Emmanuel Johnson , Gustau Camps-Valls , Raul Santos-Rodríguez , Jesus Malo

Evolutionary algorithms, inspired by natural evolution, aim to optimize difficult objective functions without computing derivatives. Here we detail the relationship between population genetics and evolutionary optimization and formulate a…

Populations and Evolution · Quantitative Biology 2023-07-19 Jakub Otwinowski , Colin LaMont

In this article, we propose a sampling-based motion planning algorithm equipped with an information-theoretic convergence criterion for incremental informative motion planning. The proposed approach allows dense map representations and…

Robotics · Computer Science 2019-05-24 Maani Ghaffari Jadidi , Jaime Valls Miro , Gamini Dissanayake

The growth rate of organisms depends both on external conditions and on internal states, such as the expression levels of various genes. We show that to achieve a criterion mean growth rate over an ensemble of conditions, the internal…

Populations and Evolution · Quantitative Biology 2007-12-31 Samuel F. Taylor , Naftali Tishby , William Bialek