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Cortical prostheses are devices implanted in the visual cortex that attempt to restore lost vision by electrically stimulating neurons. Currently, the vision provided by these devices is limited, and accurately predicting the visual…

Neurons and Cognition · Quantitative Biology 2022-09-28 Jacob Granley , Alexander Riedel , Michael Beyeler

Clinical trials previously demonstrated the notable capacity to elicit visual percepts in blind patients affected with retinal diseases by electrically stimulating the remaining neurons on the retina. However, these implants restored very…

Three critical improvements for present day and future retinal vision implants are proposed and discussed: (1) A time profile for the stimulation current that leads predominantly to transverse stimulation of nerve cells; (2) auxiliary…

Neurons and Cognition · Quantitative Biology 2012-10-22 Erich W. Schmid , Wolfgang Fink

Over the last years, deep learning methods have become an increasingly popular choice to solve tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Alexander Denker , Maximilian Schmidt , Johannes Leuschner , Peter Maass

Prosthetic vision is being applied to partially recover the retinal stimulation of visually impaired people. However, the phosphenic images produced by the implants have very limited information bandwidth due to the poor resolution and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Melani Sanchez-Garcia , Ruben Martinez-Cantin , Jose J. Guerrero

Retinal implants aim to restore functional vision despite photoreceptor degeneration, yet are fundamentally constrained by low resolution electrode arrays and patient-specific perceptual distortions. Most deployed encoders rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Henning Konermann , Yuli Wu , Emil Mededovic , Volkmar Schulz , Peter Walter , Johannes Stegmaier

This study proposes a retinal prosthetic simulation framework driven by visual fixations, inspired by the saccade mechanism, and assesses performance improvements through end-to-end optimization in a classification task. Salient patches are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Yuli Wu , Do Dinh Tan Nguyen , Henning Konermann , Rüveyda Yilmaz , Peter Walter , Johannes Stegmaier

Visual neuroprostheses are the only FDA-approved technology for the treatment of retinal degenerative blindness. Although recent work has demonstrated a systematic relationship between electrode location and the shape of the elicited visual…

Quantitative Methods · Quantitative Biology 2022-07-04 Ashley Bruce , Michael Beyeler

We propose a neural network-based framework to optimize the perceptions simulated by the in silico retinal implant model pulse2percept. The overall pipeline consists of a trainable encoder, a pre-trained retinal implant model and a…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Ivan Karetic , Johannes Stegmaier , Peter Walter , Dorit Merhof

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Galen Pogoncheff , Alvin Wang , Jacob Granley , Michael Beyeler

Neuroprostheses show potential in restoring lost sensory function and enhancing human capabilities, but the sensations produced by current devices often seem unnatural or distorted. Exact placement of implants and differences in individual…

Neurons and Cognition · Quantitative Biology 2023-10-31 Jacob Granley , Tristan Fauvel , Matthew Chalk , Michael Beyeler

Optical aberrations of optical systems cause significant degradation of imaging quality. Aberration correction by sophisticated lens designs and special glass materials generally incurs high cost of manufacturing and the increase in the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-13 Shuang Cui , Bingnan Wang , Quan Zheng

Retinal degenerative diseases cause profound visual impairment in more than 10 million people worldwide, and retinal prostheses are being developed to restore vision to these individuals. Analogous to cochlear implants, these devices…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Nicole Han , Sudhanshu Srivastava , Aiwen Xu , Devi Klein , Michael Beyeler

The increasing penetration of renewables in distribution networks calls for faster and more advanced voltage regulation strategies. A promising approach is to formulate the problem as an optimization problem, where the optimal reactive…

Optimization and Control · Mathematics 2020-02-24 Yize Chen , Yuanyuan Shi , Baosen Zhang

Sensory neuroprostheses are emerging as a promising technology to restore lost sensory function or augment human capabilities. However, sensations elicited by current devices often appear artificial and distorted. Although current models…

Machine Learning · Computer Science 2022-10-20 Jacob Granley , Lucas Relic , Michael Beyeler

We present an optimized conductance-based retina microcircuit simulator which transforms light stimuli into a series of graded and spiking action potentials through photo transduction. We use discrete retinal neuron blocks based on a…

Neurons and Cognition · Quantitative Biology 2020-01-16 Jason K. Eshraghian , Seungbum Baek , Wesley Thio , Yulia Sandamirskaya , Herbert H. C. Iu , Wei D. Lu

This paper tackles the simultaneous optimization of pose and Neural Radiance Fields (NeRF). Departing from the conventional practice of using explicit global representations for camera pose, we propose a novel overparameterized…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Shin-Fang Chng , Ravi Garg , Hemanth Saratchandran , Simon Lucey

We report the possibility of using a simple neural network for effortless restoration of low-light images inspired by the retina model, which mimics the neurophysiological principles and dynamics of various types of optical neurons. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Yurui Ming , Yuanyuan Liang

Implicit neural representations (INRs) have emerged as a promising approach for video storage and processing, showing remarkable versatility across various video tasks. However, existing methods often fail to fully leverage their…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Xinjie Zhang , Ren Yang , Dailan He , Xingtong Ge , Tongda Xu , Yan Wang , Hongwei Qin , Jun Zhang

Optical neural networks are at the forefront of computational innovation, utilizing photons as the primary carriers of information and employing optical components for computation. However, the fundamental nonlinear optical device in the…

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