Related papers: Large Language Multimodal Models for 5-Year Chroni…

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Large language models (LLMs) can generate natural language texts for various domains and tasks, but their potential for clinical text mining, a domain with scarce, sensitive, and imbalanced medical data, is underexplored. We investigate…

Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

Diabetes Mellitus, one of the leading causes of death worldwide, has no cure to date and can lead to severe health complications, such as retinopathy, limb amputation, cardiovascular diseases, and neuronal disease, if left untreated.…

Diabetic Retinopathy (DR) is a major cause of global blindness, necessitating early and accurate diagnosis. While deep learning models have shown promise in DR detection, their black-box nature often hinders clinical adoption due to a lack…

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

Although rare diseases are characterized by low prevalence, approximately 300 million people are affected by a rare disease. The early and accurate diagnosis of these conditions is a major challenge for general practitioners, who do not…

While Large Language Models (LLMs) have shown strong performance on clinical text understanding, they struggle with longitudinal prediction tasks such as dementia prognosis, which require reasoning over complex, non-monotonic symptom…

In the U.S. inpatient payment system, the Diagnosis-Related Group (DRG) is pivotal, but its assignment process is inefficient. The study introduces DRG-LLaMA, an advanced large language model (LLM) fine-tuned on clinical notes to enhance…

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Health professionals can use natural language processing (NLP) technologies when reviewing electronic health records (EHR). Machine learning free-text classifiers can help them identify problems and make critical decisions. We aim to…

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Over 30 million Americans are affected by Type II diabetes (T2D), a treatable condition with significant health risks. This study aims to develop and validate predictive models using machine learning (ML) techniques to estimate emergency…