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The alignment of language models~(LMs) with human preferences is critical for building reliable AI systems. The problem is typically framed as optimizing an LM policy to maximize the expected reward that reflects human preferences.…

Artificial Intelligence · Computer Science 2026-01-28 Zetian Sun , Dongfang Li , Xuhui Chen , Baotian Hu , Min Zhang

Direct Preference Optimization (DPO) has shown strong potential for mitigating hallucinations in Multimodal Large Language Models (MLLMs). However, existing multimodal DPO approaches often suffer from overfitting due to the difficulty…

Artificial Intelligence · Computer Science 2026-01-05 Longtian Qiu , Shan Ning , Chuyu Zhang , Jiaxuan Sun , Xuming He

Detoxifying multilingual Large Language Models (LLMs) has become crucial due to their increasing global use. In this work, we explore zero-shot cross-lingual generalization of preference tuning in detoxifying LLMs. Unlike previous studies…

Computation and Language · Computer Science 2024-11-11 Xiaochen Li , Zheng-Xin Yong , Stephen H. Bach

Minimum Bayes Risk (MBR) decoding can significantly improve translation performance of Multilingual Large Language Models (MLLMs). However, MBR decoding is computationally expensive. We show how the recently developed Reinforcement Learning…

Computation and Language · Computer Science 2024-04-15 Guangyu Yang , Jinghong Chen , Weizhe Lin , Bill Byrne

Recent advances in large vision-language models (LVLMs) have shown promise for embodied task planning, yet they struggle with fundamental challenges like dependency constraints and efficiency. Existing approaches either solely optimize…

Computation and Language · Computer Science 2025-03-14 Siyin Wang , Zhaoye Fei , Qinyuan Cheng , Shiduo Zhang , Panpan Cai , Jinlan Fu , Xipeng Qiu

Offline preference optimization methods, such as Direct Preference Optimization (DPO), offer significant advantages in aligning Large Language Models (LLMs) with human values. However, achieving optimal performance with these methods…

Machine Learning · Computer Science 2026-04-29 Peng Liao , Peijia Zheng , Lingbo Li , Shangsong Liang , Lin Chen

We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Machine Learning · Computer Science 2025-01-20 Yinkai Wang , Jiaxing He , Yuanqi Du , Xiaohui Chen , Jianan Canal Li , Li-Ping Liu , Xiaolin Xu , Soha Hassoun

It is crucial for large language models (LLMs) to follow instructions that involve multiple constraints. However, it is an unexplored area to enhance LLMs' ability to follow soft constraints. To bridge the gap, we initially design a…

Computation and Language · Computer Science 2025-06-03 Qingyu Ren , Jie Zeng , Qianyu He , Jiaqing Liang , Yanghua Xiao , Weikang Zhou , Zeye Sun , Fei Yu

Large language model reasoning is often treated as a monolithic capability, relying on binary preference supervision that fails to capture partial progress or fine-grained reasoning quality. We introduce Continuous Utility Direct Preference…

Post-training of language models, either through reinforcement learning, preference optimization or supervised finetuning, tends to sharpen the output probability distribution and reduce the diversity of generated responses. This is…

Computation and Language · Computer Science 2025-05-23 Jack Lanchantin , Angelica Chen , Shehzaad Dhuliawala , Ping Yu , Jason Weston , Sainbayar Sukhbaatar , Ilia Kulikov

Preference optimization is a critical post-training technique used to align large language models (LLMs) with human preferences, typically by fine-tuning on ranked response pairs. While methods like Direct Preference Optimization (DPO) have…

Computation and Language · Computer Science 2025-11-12 Rhitabrat Pokharel , Yufei Tao , Ameeta Agrawal

Direct Preference Optimization (DPO) aligns language models using pairwise preference comparisons, offering a simple and effective alternative to Reinforcement Learning (RL) from human feedback. However, in many practical settings, training…

Machine Learning · Computer Science 2026-05-11 Ning Liu , Chuanneng Sun , Kristina Klinkner , Shervin Malmasi

Despite recent advances in Large Video Language Models (LVLMs), they still struggle with fine-grained temporal understanding, hallucinate, and often make simple mistakes on even simple video question-answering tasks, all of which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Pritam Sarkar , Ali Etemad

Direct Preference Optimization is an offline post-SFT method for aligning language models from preference pairs, with strong results in instruction following and summarization. However, DPO's sequence-level implicit reward can be brittle…

Computation and Language · Computer Science 2026-03-03 Samah Fodeh , Linhai Ma , Ganesh Puthiaraju , Srivani Talakokkul , Afshan Khan , Ashley Hagaman , Sarah R. Lowe , Aimee Kendall Roundtree

Varied approaches for aligning language models have been proposed, including supervised fine-tuning, RLHF, and direct optimization methods such as DPO. Although DPO has rapidly gained popularity due to its straightforward training process…

Computation and Language · Computer Science 2024-08-08 Prasann Singhal , Nathan Lambert , Scott Niekum , Tanya Goyal , Greg Durrett

Alignment, endowing a pre-trained Large language model (LLM) with the ability to follow instructions, is crucial for its real-world applications. Conventional supervised fine-tuning (SFT) methods formalize it as causal language modeling…

Computation and Language · Computer Science 2024-12-18 Yuchen Fan , Yuzhong Hong , Qiushi Wang , Junwei Bao , Hongfei Jiang , Yang Song

The de novo design of ligand-binding proteins with tailored functions is essential for advancing biotechnology and molecular medicine, yet existing AI approaches are limited by scarce protein-ligand complex data. To circumvent this data…

Machine Learning · Computer Science 2026-03-03 Zhenqiao Song , Ramith Hettiarachchi , Chuan Li , Jianwen Xie , Lei Li

Although Large Language Models (LLMs) have made remarkable progress, current preference optimization methods still struggle to align directional consistency while preserving reasoning diversity. To address this limitation, we propose…

Computation and Language · Computer Science 2026-05-12 Mengyi Deng , Zhiwei Li , Xin Li , Tingyu Zhu , Yulan Yuan , Zhijiang Guo , Wei Wang

Aligning large language models (LLMs) depends on high-quality datasets of human preference labels, which are costly to collect. Although active learning has been studied to improve sample efficiency relative to passive collection, many…

Machine Learning · Computer Science 2026-02-03 Yao Zhao , Kwang-Sung Jun

Matching job descriptions (JDs) with suitable talent requires models capable of understanding not only textual similarities between JDs and candidate resumes but also contextual factors such as geographical location and academic seniority.…

Computation and Language · Computer Science 2025-03-17 Yafei Zhang , Murray Wang , Yu Wang , Xiaohui Wang