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A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin…

Medical Physics · Physics 2017-12-04 Chris Wu , Tanay Tandon

We demonstrate the design, fabrication and use of a dual electrode PMUT (Piezoelectric Micromachined Ultrasound Transducer) integrated with a microfluidic channel as a fluid density sensor in both static and dynamic density-change…

Conventional spectrometer and polarimeter systems rely on bulky optics, fundamentally limiting compact integration and hindering multi-dimensional optical sensing capabilities. Here, we propose a spectropolarimeter enabled by…

Optics · Physics 2026-04-13 Jumin Qiu , Tingting Liu , Chenxuan Xiang , Tianbao Yu , Qiegen Liu , Shuyuan Xiao

In this study we present an interferometric technique based on multiple wavelengths to capture the transient free surface contour of nanoliter drops spreading on a wettable surface, in particular close to the three-phase contact line.…

Fluid Dynamics · Physics 2024-12-24 Timo Richter , Mathis Fricke , Peter Stephan , Cameron Tropea , Jeanette Hussong

The investigation of liquid flow at the nanoscale is a key area of applied research with high relevance to Physics, Chemistry and Biology. We introduce a method and a device that allows to spatially resolve liquid flow by integrating an…

Mesoscale and Nanoscale Physics · Physics 2016-08-24 R. F. Neumann , M. Engel , M. Steiner

Artificial nanostructures with ultrafine and deep-subwavelength feature sizes have emerged as a paradigm-shifting platform to advanced light field management, becoming a key building block for high-performance integrated optoelectronics and…

We report a pilot study with a wide-field laser Doppler detection scheme used to perform laser Doppler anemometry and imaging of particle seeded microflow. The optical field carrying the local scatterers (particles) dynamic state, as a…

Optics · Physics 2013-12-24 Michel Gross , Michael Atlan , Jacques Leng

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

A novel approach for automated high throughput NMR spectroscopy with improved mass-sensitivity is accomplished by integrating microfluidic technologies and micro-NMR resonators. A flow system is utilized to transport a sample of interest…

Instrumentation and Detectors · Physics 2021-04-20 Omar Nassar , Mazin Jouda , Michael Rapp , Dario Mager , Jan G. Korvink , Neil MacKinnon

Exploring and controlling the physical factors that determine the topography of thin liquid dielectric films are of interest in manifold fields of research in physics, applied mathematics, and engineering and have been a key aspect of many…

Optics · Physics 2019-08-27 Shimon Rubin , Brandon Hong , Yeshaiahu Fainman

Underwater environments impose severe constraints on conventional imaging systems and demand solutions that balance high-quality sensing with strict resource efficiency. While emerging event cameras offer a promising alternative, their…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Pei Zhang , Yunkai Liang , Kaiqiang Wang

This report introduces a novel optofluidic platform based on piezo-MEMS technology, capable of identifying subtle variations in the fluid concentration. The system utilizes piezoelectric micromachined ultrasound transducers (PMUTs) as…

Technologies for sequencing (reading) and synthesizing (writing) DNA have progressed on a Moore's law-like trajectory over the last three decades. This has motivated the idea of using DNA for data storage. Theoretically, DNA-based storage…

Emerging Technologies · Computer Science 2023-07-07 Ajay Manicka , Andrew Stephan , Sriram Chari , Gemma Mendonsa , Peyton Okubo , John Stolzberg-Schray , Anil Reddy , Marc Riedel

In the recent years, there has been a growing interest in droplet-based (digital) microfluidics for which, reliable means of droplet manipulation are required. In this study we demonstrate thermal actuation of droplets on liquid platforms,…

Fluid Dynamics · Physics 2010-10-19 Ehsan Yakhshi-Tafti , Hyoung J. Cho , Ranganathan Kumar

The recent development of opto-mechano-fluidic resonators has provided -- by harnessing photon radiation pressure -- a new microfluidics platform for the optical sensing of fluid density and bulk modulus. Here we show that fluid viscosity…

Optics · Physics 2014-07-15 Kewen Han , Kaiyuan Zhu , Gaurav Bahl

A major limitation of transient optical spectroscopy is that relatively high laser fluences are required to enable broadband, multichannel detection with acceptable signal-to-noise levels. Under typical experimental conditions, many…

Optics · Physics 2023-05-03 Siedah J. Hall , Peter J. Budden , Anne Zats , Matthew Y. Sfeir

We developed a rapid polymorphic screening approach based on contracting sessile microdroplets which offers several advantages: (1) achieves very high supersaturation to facilitate formation of metastable forms (2) allows systematic…

Soft Condensed Matter · Physics 2024-08-23 Ruel Cedeno , Romain Grossier , Nadine Candoni , Stéphane Veesler

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

The advent in recent years of highly parallelized microfluidic chemical reaction systems necessitates an understanding of all fluid dynamic time scales including the often neglected millisecond time scale of the inertia of the liquid. We…

Fluid Dynamics · Physics 2011-10-28 Soren Vedel , Laurits H. Olesen , Henrik Bruus

Manipulating fluids by light at the nanoscale has been a long-sought-after goal for lab-on-a-chip applications. Plasmonic heating has been demonstrated to control microfluidic dynamics due to the enhanced and confined light absorption from…

Optics · Physics 2023-08-01 Sen Yang , Justus C. Ndukaife