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Deep learning (DL) models have achieved paradigm-changing performance in many fields with high dimensional data, such as images, audio, and text. However, the black-box nature of deep neural networks is a barrier not just to adoption in…

Machine Learning · Computer Science 2020-02-25 Parmita Mehta , Stephen Portillo , Magdalena Balazinska , Andrew Connolly

T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) are essential components for cervical cancer diagnosis. However, combining these channels for training deep learning models are challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Reza Kalantar , Sebastian Curcean , Jessica M Winfield , Gigin Lin , Christina Messiou , Matthew D Blackledge , Dow-Mu Koh

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yongxiang Huang , Albert C. S. Chung

Deep Learning models have been successfully utilized to extract clinically actionable insights from routinely available histology data. Generally, these models require annotations performed by clinicians, which are scarce and costly to…

Machine Learning · Computer Science 2024-03-13 Tim Lenz , Omar S. M. El Nahhas , Marta Ligero , Jakob Nikolas Kather

Deep learning based generative adversarial networks (GAN) can effectively perform image reconstruction with under-sampled MR data. In general, a large number of training samples are required to improve the reconstruction performance of a…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 Jun Lv , Guangyuan Li , Xiangrong Tong , Weibo Chen , Jiahao Huang , Chengyan Wang , Guang Yang

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

Machine Learning · Computer Science 2026-02-13 Ankita Paul , Wenyi Wang

Medical image segmentation has been significantly advanced by deep learning (DL) techniques, though the data scarcity inherent in medical applications poses a great challenge to DL-based segmentation methods. Self-supervised learning offers…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Binyan Hu , A. K. Qin

In many real-world applications of deep learning, estimation of a target may rely on various types of input data modes, such as audio-video, image-text, etc. This task can be further complicated by a lack of sufficient data. Here we propose…

Computer Vision and Pattern Recognition · Computer Science 2020-06-17 Levi McClenny , Mulugeta Haile , Vahid Attari , Brian Sadler , Ulisses Braga-Neto , Raymundo Arroyave

Effective recognition of acute and difficult-to-heal wounds is a necessary step in wound diagnosis. An efficient classification model can help wound specialists classify wound types with less financial and time costs and also help in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ramin Mousa , Hadis Taherinia , Khabiba Abdiyeva , Amir Ali Bengari , Mohammadmahdi Vahediahmar

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Accurate localization of tumor regions from hematoxylin and eosin-stained whole-slide images is fundamental for translational research including spatial analysis, molecular profiling, and tissue architecture investigation. However, deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Brian Isett , Rebekah Dadey , Aofei Li , Ryan C. Augustin , Kate Smith , Aatur D. Singhi , Qiangqiang Gu , Riyue Bao

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Multi-task learning (MTL) is a subfield of machine learning in which multiple tasks are simultaneously learned by a shared model. Such approaches offer advantages like improved data efficiency, reduced overfitting through shared…

Machine Learning · Computer Science 2020-09-22 Michael Crawshaw

Hand-crafted features extracted from dynamic contrast-enhanced magnetic resonance images (DCE-MRIs) have shown strong predictive abilities in characterization of breast lesions. However, heterogeneity across medical image datasets hinders…

Medical Physics · Physics 2017-01-17 Natalia Antropova , Benjamin Huynh , Maryellen Giger

We present a novel framework that can combine multi-domain learning (MDL), data imputation (DI) and multi-task learning (MTL) to improve performance for classification and regression tasks in different domains. The core of our method is an…

Machine Learning · Computer Science 2020-03-18 Andre Mendes , Julian Togelius , Leandro dos Santos Coelho

Early prostate cancer detection and staging from MRI are extremely challenging tasks for both radiologists and deep learning algorithms, but the potential to learn from large and diverse datasets remains a promising avenue to increase their…

Computer Vision and Pattern Recognition · Computer Science 2022-06-14 Abhejit Rajagopal , Ekaterina Redekop , Anil Kemisetti , Rushi Kulkarni , Steven Raman , Kirti Magudia , Corey W. Arnold , Peder E. Z. Larson

Deep learning (DL) has recently emerged as a pivotal technology for enhancing magnetic resonance imaging (MRI), a critical tool in diagnostic radiology. This review paper provides a comprehensive overview of recent advances in DL for MRI…

Machine Learning · Computer Science 2024-04-25 Reinhard Heckel , Mathews Jacob , Akshay Chaudhari , Or Perlman , Efrat Shimron

Deep Learning (DL) has shown potential in accelerating Magnetic Resonance Image acquisition and reconstruction. Nevertheless, there is a dearth of tailored methods to guarantee that the reconstruction of small features is achieved with high…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Francesco Calivá , Kaiyang Cheng , Rutwik Shah , Valentina Pedoia

Tumor mutational burden (TMB) is a potential genomic biomarker of immunotherapy. However, TMB detected through whole exome sequencing lacks clinical penetration in low-resource settings. In this study, we proposed a multi-scale deep…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Siteng Chen , Jinxi Xiang , Xiyue Wang , Jun Zhang , Sen Yang , Junzhou Huang , Wei Yang , Junhua Zheng , Xiao Han
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