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Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

Large language models (LLMs) such as GPT-4 have exhibited remarkable performance in a variety of tasks, but this strong performance often comes with the high expense of using paid API services. In this paper, we are motivated to study…

Assessing the effectiveness of large language models (LLMs) in performing different tasks is crucial for understanding their strengths and weaknesses. This paper presents Hierarchical Prompting Taxonomy (HPT), grounded on human cognitive…

Researchers often rely on humans to code (label, annotate, etc.) large sets of texts. This kind of human coding forms an important part of social science research, yet the coding process is both resource intensive and highly variable from…

Chemically accurate and comprehensive studies of the virtual space of all possible molecules are severely limited by the computational cost of quantum chemistry. We introduce a composite strategy that adds machine learning corrections to…

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

High-quality conversational datasets are crucial for the successful development of Intelligent Tutoring Systems (ITS) that utilize a Large Language Model (LLM) backend. Synthetic student-teacher dialogues, generated using advanced GPT-4…

We utilise the power of Large Language Models (LLMs), in particular GPT4, to be prompt engineered into performing an arbitrary task. Here, we give the model some human priors via text, along with some typical procedures for solving the ARC…

Multimodal large language models (MLLMs) carry the potential to support humans in processing vast amounts of information. While MLLMs are already being used as a fact-checking tool, their abilities and limitations in this regard are…

Large language models (LLMs) have undergone significant expansion and have been increasingly integrated across various domains. Notably, in the realm of robot task planning, LLMs harness their advanced reasoning and language comprehension…

Systematic reviews are vital for guiding practice, research, and policy, yet they are often slow and labour-intensive. Large language models (LLMs) could offer a way to speed up and automate systematic reviews, but their performance in such…

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Large Language Models (LLMs) have been applied to Math Word Problems (MWPs) with transformative impacts, revolutionizing how these complex problems are approached and solved in various domains including educational settings. However, the…

Large language models (LLMs) finetuned to follow human instruction have recently exhibited significant capabilities in various English NLP tasks. However, their performance in grammatical error correction (GEC), especially on languages…

Large Language Models (LLMs) have garnered considerable interest within both academic and industrial. Yet, the application of LLMs to graph data remains under-explored. In this study, we evaluate the capabilities of four LLMs in addressing…

Large language models (LLMs) can be used as accessible and intelligent chatbots by constructing natural language queries and directly inputting the prompt into the large language model. However, different prompt' constructions often lead to…

This paper introduces AnalyticsGPT, an intuitive and efficient large language model (LLM)-powered workflow for scientometric question answering. This underrepresented downstream task addresses the subcategory of meta-scientific questions…

Expert feedback lays the foundation of rigorous research. However, the rapid growth of scholarly production and intricate knowledge specialization challenge the conventional scientific feedback mechanisms. High-quality peer reviews are…