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Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

The recent success of large language models (LLMs) trained on static, pre-collected, general datasets has sparked numerous research directions and applications. One such direction addresses the non-trivial challenge of integrating…

Machine Learning · Computer Science 2024-11-26 Haizhou Shi , Zihao Xu , Hengyi Wang , Weiyi Qin , Wenyuan Wang , Yibin Wang , Zifeng Wang , Sayna Ebrahimi , Hao Wang

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Current approaches to data discovery match keywords between metadata and queries. This matching requires researchers to know the exact wording that other researchers previously used, creating a challenging process that could lead to missing…

Human-Computer Interaction · Computer Science 2025-10-03 Maura E Halstead , Mark A. Green , Caroline Jay , Richard Kingston , David Topping , Alexander Singleton

Digital twin technology is a transformative innovation driving the digital transformation and intelligent optimization of manufacturing systems. By integrating real-time data with computational models, digital twins enable continuous…

Emerging Technologies · Computer Science 2025-03-05 Linyao Yang , Shi Luo , Xi Cheng , Lei Yu

Data augmentation has been widely used to improve deep neural networks in many research fields, such as computer vision. However, less work has been done in the context of text, partially due to its discrete nature and the complexity of…

Computation and Language · Computer Science 2021-01-12 Ping Yu , Ruiyi Zhang , Yang Zhao , Yizhe Zhang , Chunyuan Li , Changyou Chen

Recently, Large Language Models (LLMs) have shown impressive language capabilities. While most of the existing LLMs have very unbalanced performance across different languages, multilingual alignment based on translation parallel data is an…

Computation and Language · Computer Science 2024-06-19 Shimao Zhang , Changjiang Gao , Wenhao Zhu , Jiajun Chen , Xin Huang , Xue Han , Junlan Feng , Chao Deng , Shujian Huang

Large Language Models (LLMs) have demonstrated strong reasoning capabilities across various tasks. However, even minor variations in query phrasing, despite preserving the underlying semantic meaning, can significantly affect their…

Computation and Language · Computer Science 2025-02-26 Yihang Yao , Zhepeng Cen , Miao Li , William Han , Yuyou Zhang , Emerson Liu , Zuxin Liu , Chuang Gan , Ding Zhao

Large Language Models (LLMs) are rapidly reshaping machine translation (MT), particularly by introducing instruction-following, in-context learning, and preference-based alignment into what has traditionally been a supervised…

Computation and Language · Computer Science 2026-04-29 Baban Gain , Dibyanayan Bandyopadhyay , Asif Ekbal , Trilok Nath Singh

This position paper proposes a data-centric viewpoint of AI research, focusing on large language models (LLMs). We start by making the key observation that data is instrumental in the developmental (e.g., pretraining and fine-tuning) and…

Recent years have witnessed remarkable progress made in large language models (LLMs). Such advancements, while garnering significant attention, have concurrently elicited various concerns. The potential of these models is undeniably vast;…

Computation and Language · Computer Science 2023-09-27 Tianhao Shen , Renren Jin , Yufei Huang , Chuang Liu , Weilong Dong , Zishan Guo , Xinwei Wu , Yan Liu , Deyi Xiong

Large Language Models (LLMs) have achieved remarkable success across a wide array of tasks. Due to the impressive planning and reasoning abilities of LLMs, they have been used as autonomous agents to do many tasks automatically. Recently,…

Computation and Language · Computer Science 2024-04-22 Taicheng Guo , Xiuying Chen , Yaqi Wang , Ruidi Chang , Shichao Pei , Nitesh V. Chawla , Olaf Wiest , Xiangliang Zhang

Large Language Models (LLMs), AI-driven models that can achieve general-purpose language understanding and generation, have emerged as a transformative force, revolutionizing fields well beyond Natural Language Processing (NLP) and…

Information Theory · Computer Science 2024-02-27 Ali Maatouk , Nicola Piovesan , Fadhel Ayed , Antonio De Domenico , Merouane Debbah

Pretrained large language models (LLMs) are currently state-of-the-art for solving the vast majority of natural language processing tasks. While many real-world applications still require fine-tuning to reach satisfactory levels of…

Large language models (LLMs) are gaining increasing popularity in both academia and industry, owing to their unprecedented performance in various applications. As LLMs continue to play a vital role in both research and daily use, their…

Computation and Language · Computer Science 2024-01-01 Yupeng Chang , Xu Wang , Jindong Wang , Yuan Wu , Linyi Yang , Kaijie Zhu , Hao Chen , Xiaoyuan Yi , Cunxiang Wang , Yidong Wang , Wei Ye , Yue Zhang , Yi Chang , Philip S. Yu , Qiang Yang , Xing Xie

Large Language Model (LLM) agents are transforming education by automating complex pedagogical tasks and enhancing both teaching and learning processes. In this survey, we present a systematic review of recent advances in applying LLM…

Computers and Society · Computer Science 2026-02-05 Zhendong Chu , Shen Wang , Jian Xie , Tinghui Zhu , Yibo Yan , Jinheng Ye , Aoxiao Zhong , Xuming Hu , Jing Liang , Philip S. Yu , Qingsong Wen

Data scarcity is a problem that occurs in languages and tasks where we do not have large amounts of labeled data but want to use state-of-the-art models. Such models are often deep learning models that require a significant amount of data…

Computation and Language · Computer Science 2023-02-23 Domagoj Pluščec , Jan Šnajder

Large language models (LLMs) rely on pretraining on massive and heterogeneous corpora, where training data composition has a decisive impact on training efficiency and downstream generalization under realistic compute and data budget…

Computation and Language · Computer Science 2026-04-21 Zhuo Chen , Yuxuan Miao , Supryadi , Deyi Xiong

Classification tasks are typically handled using Machine Learning (ML) models, which lack a balance between accuracy and interpretability. This paper introduces a new approach for classification tasks using Large Language Models (LLMs) in…

Computation and Language · Computer Science 2025-01-03 Praneeth Vadlapati

Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works…

Computation and Language · Computer Science 2024-10-18 Humza Naveed , Asad Ullah Khan , Shi Qiu , Muhammad Saqib , Saeed Anwar , Muhammad Usman , Naveed Akhtar , Nick Barnes , Ajmal Mian
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