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The Fusion Synthesis Engine (FUSE) is a state-of-the-art software suite designed to revolutionize fusion power plant design. FUSE integrates first-principle models, machine learning, and reduced models into a unified framework, enabling…

The progression of scientific computing resources has enabled the numerical approximation of mathematical models describing complex physical phenomena. A significant portion of researcher time is typically dedicated to the development of…

Mathematical Software · Computer Science 2015-06-22 Paul T. Bauman , Roy H. Stogner

Research in software engineering is essential for improving development practices, leading to reliable and secure software. Leveraging the principles of quantum physics, quantum computing has emerged as a new computational paradigm that…

Software Engineering · Computer Science 2025-02-14 Ashis Kumar Mandal , Md Nadim , Chanchal K. Roy , Banani Roy , Kevin A. Schneider

We analyze the computational complexity of basic reconfiguration problems for the recently introduced surface Chemical Reaction Networks (sCRNs), where ordered pairs of adjacent species nondeterministically transform into a different…

This paper proposes a novel neural network framework, denoted as spectral integrated neural networks (SINNs), for resolving three-dimensional forward and inverse dynamic problems. In the SINNs, the spectral integration method is applied to…

Numerical Analysis · Mathematics 2024-01-09 Lin Qiu , Fajie Wang , Wenzhen Qu , Yan Gu , Qing-Hua Qin

Modern applications of atomic physics, including the determination of frequency standards, and the analysis of astrophysical spectra, require prediction of atomic properties with exquisite accuracy. For complex atomic systems,…

Atomic Physics · Physics 2024-08-02 Pavlo Bilous , Charles Cheung , Marianna Safronova

I propose a novel approach to balancing equations that is applicable to all chemical-reaction equations; it is readily accessible to students via scientific calculators and basic computer spreadsheets that have a matrix-inversion…

Chemical Physics · Physics 2011-10-20 Lawrence R. Thorne

Accurate prediction of protein-ligand binding affinity is crucial for rapid and efficient drug development. Recently, the importance of predicting binding affinity has led to increased attention on research that models the three-dimensional…

Machine Learning · Computer Science 2024-07-17 Seungyeon Choi , Sangmin Seo , Sanghyun Park

Scanning tunneling and atomic force microscopies (STM/nc-AFM) are rapidly progressing to offer unprecedented spatial resolution of a diverse array of chemical species. In particular, they are employed to characterize on-surface chemical…

Mesoscale and Nanoscale Physics · Physics 2022-05-12 Jack Hellerstedt , Aleš Cahlík , Martin Švec , Oleksandr Stetsovych , Tyler Hennen

Hybrid quantum-classical computing algorithms offer significant potential for accelerating the calculation of the electronic structure of strongly correlated molecules. In this work, we present the first quantum simulation of conical…

Biology is perhaps the most complex of the sciences, given the incredible variety of chemical species that are interconnected in spatial and temporal pathways that are daunting to understand. Their interconnections lead to emergent…

Biological Physics · Physics 2023-09-11 Henry V. Jakubowski , Henry Agnew , Bartholomew E. Jardine , Herbert M. Sauro

\textsc{Quantum Package} is an open-source programming environment for quantum chemistry specially designed for wave function methods. Its main goal is the development of determinant-driven selected configuration interaction (sCI) methods…

Data-adaptive (machine learning-based) effect estimators are increasingly popular to reduce bias in high-dimensional bioinformatic and clinical studies (e.g. real-world data, target trials, -omic discovery). Their relative statistical…

Methodology · Statistics 2022-06-13 Xiang Meng , Jonathan Huang

The development of new electronic structure methods is a very time consuming and error prone process when done by hand. SpinAdaptedSecondQuantization is an open-source Julia package we have developed for working with automated electronic…

Chemical Physics · Physics 2025-08-26 Marcus T. Lexander , Tor S. Haugland , Federico Rossi , Henrik Koch

Chemical reactor networks (CRNs) enable simulations of combustion reactors with detailed chemical kinetics and strongly simplified flow structure. In this paper, the implementation of a reactor component with less idealized flow structure,…

Fluid Dynamics · Physics 2023-05-22 Lisanne Gossel , Mathis Fricke , Dieter Bothe

A detailed algorithmic explanation is required for how a network of chemical reactions can generate the sophisticated behavior displayed by living cells. Though several previous works have shown that reaction networks are computationally…

Emerging Technologies · Computer Science 2018-04-25 Muppirala Viswa Virinchi , Abhishek Behera , Manoj Gopalkrishnan

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

Dynamical Systems · Mathematics 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz

Molecular circuits capable of autonomous learning could unlock novel applications in fields such as bioengineering and synthetic biology. To this end, existing chemical implementations of neural computing have mainly relied on emulating…

Machine Learning · Computer Science 2025-09-23 Rajiv Teja Nagipogu , John H. Reif

CHEMSMART (Chemistry Simulation and Modeling Automation Toolkit) is an open-source, Python-based framework designed to streamline quantum chemistry workflows for homogeneous catalysis and molecular modeling. By integrating job preparation,…

Chemical Physics · Physics 2025-08-28 Xinglong Zhang , Huiwen Tan , Jingyi Liu , Zihan Li , Lewen Wang , Benjamin W. J. Chen

Accurate quantum chemistry simulations remain challenging on classical computers for problems of industrially relevant sizes and there is reason for hope that quantum computing may help push the boundaries of what is technically feasible.…

Quantum Physics · Physics 2021-03-17 Vincent E. Elfving , Marta Millaruelo , José A. Gámez , Christian Gogolin