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The paper investigates the problem of fitting protein complexes into electron density maps. They are represented by high-resolution cryoEM density maps converted into overlapping matrices and partly show a structure of a complex. The…

Optimization and Control · Mathematics 2017-01-10 Roman Pogodin , Alexander Katrutsa , Sergei Grudinin

The goal of quantum circuit transformation is to map a logical circuit to a physical device by inserting additional gates as few as possible in an acceptable amount of time. We present an effective approach called TSA to construct the…

Quantum Physics · Physics 2024-07-25 Hui Jiang , Yuxin Deng , Ming Xu

Covariance tapering is a popular approach for reducing the computational cost of spatial prediction and parameter estimation for Gaussian process models. However, tapering can have poor performance when the process is sampled at spatially…

Computation · Statistics 2016-02-22 David Bolin , Jonas Wallin

For approximate inference in the generalized quadratic equations model, many state-of-the-art algorithms lack any prior knowledge of the target signal structure, exhibits slow convergence, and can not handle any analytic prior knowledge of…

Information Theory · Computer Science 2024-02-27 Huimin Zhu

In this work we present a new methodology to study the structure of the configuration spaces of hard combinatorial problems. It consists in building the network that has as nodes the locally optimal configurations and as edges the weighted…

Neural and Evolutionary Computing · Computer Science 2012-07-19 Fabio Daolio , Marco Tomassini , Sébastien Verel , Gabriela Ochoa

Quadratic Unconstrained Binary Optimization (QUBO) is a general-purpose modeling framework for combinatorial optimization problems and is a requirement for quantum annealers. This paper utilizes the eigenvalue decomposition of the…

Optimization and Control · Mathematics 2021-06-22 Amit Verma , Mark Lewis

An assignment problem arises when there exists a set of tasks that must be allocated to a set of agents. The bottleneck assignment problem (BAP) has the objective of minimising the most costly allocation of a task to an agent. Under certain…

Optimization and Control · Mathematics 2020-08-26 Mitchell Khoo , Tony A. Wood , Chris Manzie , Iman Shames

In this paper, we consider the computational protein design (CPD) problem, which is usually modeled as a 0/1 programming and is extremely challenging due to its combinatorial properties. We propose an efficient algorithm for solving it.…

Optimization and Control · Mathematics 2024-12-30 Yukai Zheng , Weikun Chen , Qingna Li

The classification problem of structured data can be solved with different strategies: a supervised learning approach, starting from a labeled training set, and an unsupervised learning one, where only the structure of the patterns in the…

Disordered Systems and Neural Networks · Physics 2021-11-09 Mauro Pastore

Recently, many graph matching methods that incorporate pairwise constraint and that can be formulated as a quadratic assignment problem (QAP) have been proposed. Although these methods demonstrate promising results for the graph matching…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Fudong Wang , Nan Xue , Yipeng Zhang , Xiang Bai , Gui-Song Xia

We give a quantum algorithm for solving instances of the satisfiability problem, based on adiabatic evolution. The evolution of the quantum state is governed by a time-dependent Hamiltonian that interpolates between an initial Hamiltonian,…

Quantum Physics · Physics 2007-05-23 Edward Farhi , Jeffrey Goldstone , Sam Gutmann , Michael Sipser

The solution-space structure of the 3-Satisfiability Problem (3-SAT) is studied as a function of the control parameter alpha (ratio of number of clauses to the number of variables) using numerical simulations. For this purpose, one has to…

Disordered Systems and Neural Networks · Physics 2015-05-18 Alexander Mann , A. K. Hartmann

Boolean satisfiability (SAT) is a propositional logic problem of determining whether an assignment of variables satisfies a Boolean formula. Many combinatorial optimization problems can be formulated in Boolean SAT logic -- either as k-SAT…

Optimization and Control · Mathematics 2026-03-12 Robert Simon Fong , Yanming Song , Alexander Yosifov

We present quadratically convergent algorithms to compute the extremal value of a real parameter for which a given rational transfer function of a linear time-invariant system is passive. This problem is formulated for both continuous-time…

Optimization and Control · Mathematics 2022-05-26 Tim Mitchell , Paul Van Dooren

A variant of the well-known Assignment Problem is studied in this paper, where pairs of assignments are conflicting, and cannot be selected at the same time. This configures a set of hard constraints. The problem, which models real…

Optimization and Control · Mathematics 2025-06-06 Roberto Montemanni , Derek H. Smith

We consider the problem of solving a large-scale Quadratically Constrained Quadratic Program. Such problems occur naturally in many scientific and web applications. Although there are efficient methods which tackle this problem, they are…

Machine Learning · Statistics 2017-10-04 Kinjal Basu , Ankan Saha , Shaunak Chatterjee

In this paper, we solve a maximization problem where the objective function is quadratic and convex or concave and the constraints set is the reachable value set of a convergent discrete-time affine system. Moreover, we assume that the…

Optimization and Control · Mathematics 2020-06-18 Assalé Adjé

Field-Programmable Gate Arrays (FPGAs) have asserted themselves as vital assets in contemporary computing by offering adaptable, reconfigurable hardware platforms. FPGA-based accelerators incubate opportunities for breakthroughs in areas,…

We construct a set of instances of 3SAT which are not solved efficiently using the simplest quantum adiabatic algorithm. These instances are obtained by picking random clauses all consistent with two disparate planted solutions and then…

Quantum Physics · Physics 2012-03-30 Edward Farhi , Jeffrey Goldstone , David Gosset , Sam Gutmann , Harvey B. Meyer , Peter Shor

We consider three known bounds for the quadratic assignment problem (QAP): an eigenvalue, a convex quadratic programming (CQP), and a semidefinite programming (SDP) bound. Since the last two bounds were not compared directly before, we…

Optimization and Control · Mathematics 2020-12-15 Daniel Brosch , Etienne de Klerk